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SGI Breakthrough Technology Empowers Genome Center Research Around the World
Date:4/30/2008

found in some lakes and rivers in the east and south China area. To study the parasite evolution, improve disease diagnosis in the very early stages, and develop more effective drugs to treat disease, bioscientists at the China National Human Genome Center (CHGC) in Shanghai are using a combination of SGI(R) RASC(TM) (Reconfigurable Application-Specific Computing) technology, an accelerated version of BLAST-n (Basic Local Alignment Search Tool for nucleotides) software developed by Mitrionics, and the SGI(R) Altix(R) server platform.

CHGC implemented blood fluke genomics sequencing using the SGI RASC Appliance for Bioinformatics and SGI InfiniteStorage 350 storage solution (See separate release July 24, 2007). CHGC bioscientists achieve fast query times with the SGI InfiniteStorage 350, which ensures the data generated by the CHGC research, reaching hundreds of gigabytes in size, is both protected and available to maximize analysis.

"Shortened time to results is critical to our success. With the blood fluke genome research, we have 300 million base pairs to study, and have 6-7 times more calculations in each step. The large shared memory and ease-of-use with SGI RASC and SGI server and storage systems enables our scientists to focus on achieving results faster and not spending valuable time on computer science," said Dr. Zhou, Deputy Director of Bioinformatics Department, CHGC.

The Mitrion accelerated BLAST-n running on the SGI RASC Appliance for Bioinformatics runs large queries up to 19 times faster than a single-core cluster powered by AMD Opteron 8820 SE processors, and production runs of thousands of smaller queries by up to 60 times faster.

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