The goal of the Natural Products component of Senomyx's Sweet Taste Program is to discover and develop novel no- or low-calorie natural high intensity sweeteners and natural sweet taste modifiers. The Company has achieved taste proofs-of-concept with the identification of a natural sucrose modifier and a natural sweetener. Continuing activities include further expansion of Senomyx's natural products library, high-throughput screening of these plant-derived samples, and additional taste tests of samples of interest.
Cooling Taste Program: The goal of the Cooling Taste Program is to identify novel cooling agents that have advantages over currently available agents such as menthol. Definitive safety studies and other development activities in preparation for future regulatory filings are underway for S2227, a new cooling agent. Firmenich has exclusive commercialization rights for S2227. Additional new cooling agents are being evaluated for potential future commercialization.Savory Taste Program: Senomyx received notification that S643, a new savory flavor, has been granted a GRAS designation. S643 is the twelfth flavor ingredient for which the Company has been granted GRAS regulatory approval. S643 is exclusively licensed to a collaborator for use in Asia, and Senomyx retains all rights to S643 in all other geographies.
Salt Taste Program: The goal of Senomyx's Salt Taste Program is to identify flavor ingredients that allo
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