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SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2009 FINANCIAL RESULTS
Date:8/4/2009

e on the discovery and development of bitter blockers that modulate and control bitterness in certain soy-based products. Senomyx bitter blockers have demonstrated a taste proof-of-concept with several representative soy samples from Solae, as well as soy-based product prototypes. Optimization of the bitter blockers and additional taste tests are ongoing.

- Salt Enhancer Program: The goal of the Salt Enhancer Program is to identify flavor ingredients that allow a significant reduction of sodium in foods and beverages yet maintain the salty taste desirable to consumers. Senomyx has identified more than 250 enhancers of sodium chloride (table salt) that are active in the proprietary screening assays based on SNMX-29, the protein Senomyx believes is the primary receptor responsible for human salt taste perception. These enhancers represent 12 diverse sample classes and therefore may provide numerous opportunities for the discovery of a new flavor ingredient that enables a reduction in the use of salt. The enhancers are being optimized and evaluated in taste tests.

- Cool Flavor Program: The goal of the Cool Flavor Program is to identify novel cooling flavors that do not have the limitations of currently available agents. Senomyx has discovered cool flavor enhancers that provided a taste proof-of-concept. Additional samples are being screened in the Company's proprietary high-throughput assay designed to identify potential new cooling agents. Samples that are active in the assay will be evaluated in taste tests to determine their cooling taste effect.

Financial Review:

"The initial license fee payment associated with our new Firmenich agreement provides Senomyx with non-dilutive cash," said John Poyhonen, Senior Vice President, Chief Financial and Business Officer. "In addition, the second quarter financial results for net loss and cash utilization were in-line with th
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