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SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2009 FINANCIAL RESULTS
Date:8/4/2009

Senomyx is also continuing to increase the number of granted patents in its intellectual property portfolio of proprietary taste receptor technologies. As of June 30, 2009, Senomyx is the owner or exclusive licensee of 173 issued patents and 391 pending patent applications in the U.S., Europe, and elsewhere.

Program Updates:

- Savory Enhancer Program: The primary applications of the Company's savory flavor ingredients are to reduce or replace monosodium glutamate (MSG) and to enhance the savory taste of foods by combining Senomyx's savory flavors with other ingredients to create unique new flavors. Nestle is currently marketing a small number of new bouillon and culinary aid food products that contain Senomyx's savory flavor ingredients in the Pacific Rim and Latin America. In addition, Nestle has been conducting product development and consumer testing with both new and reformulated established products in larger countries that are high-volume users of MSG. Senomyx anticipates that Nestle will initiate commercialization of established products containing the savory flavor ingredients later this year.

- Sweet Enhancer Program: The primary goal for this program is to identify flavor ingredients that allow a significant reduction of sweeteners in food and beverage products while maintaining the desired sweet taste. Senomyx discovered and developed S2383, a novel enhancer of the high-intensity sweetener sucralose that enables up to a 75% reduction of sucralose in product prototypes without compromising the sweet intensity or producing off-tastes. Use of S2383 may also result in an improved taste compared to sucralose alone when incorporated into a flavor system. Senomyx and Firmenich entered into a collaboration in November 2008 under which Firmenich has exclusive rights to commercialize S2383 on a worldwide basis in virtually all product categories. S2383 has been granted a GRAS (General
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