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SENOMYX ANNOUNCES APPOINTMENT OF DAVID L. LINEMEYER, PH.D., AS VICE PRESIDENT, BIOLOGY
Date:5/27/2009

ry of several new flavor ingredients, including S2383, a novel enhancer of the high intensity sweetener sucralose that is the subject of pre-commercialization activities. In addition, S6973, a sucrose enhancer that enables the reduction of up to 50% of the sugar in food and beverage prototypes, and S0812 and S6821, promising bitter blockers, are undergoing development to support regulatory filings and future commercialization.

About Senomyx, Inc. (www.senomyx.com)

Senomyx is a leading company using proprietary taste receptor technologies to discover and develop novel flavor ingredients in the savory, sweet, salt, bitter, and cooling areas. Senomyx has entered into product discovery, development, and commercialization collaborations with seven of the world's foremost food, beverage, and ingredient supply companies: Ajinomoto Co., Inc., Cadbury plc, Campbell Soup Company, The Coca-Cola Company, Firmenich SA, Nestle SA, and Solae. Nestle is currently marketing products that contain one of Senomyx's flavor ingredients. For more information, please visit www.senomyx.com.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding Senomyx's ability to discover novel compounds and create new flavor ingredients that are beneficial to our collaborators and Senomyx's ability to successfully complete development activities to support regulatory filings and future commercialization of S6973
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SOURCE Senomyx, Inc.
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