Navigation Links
SEEK Announces Clinical Proof of Efficacy in HIV Vaccine Phase Ib/II Human Trial
Date:7/18/2011

LONDON, July 18, 2011 /PRNewswire/ --


90% Reduction in HIV Viral Load Demonstrated Compared With Normal Disease Progression

SEEK, a privately owned biopharmaceutical company specializing in immunology, announces today that it has completed a Phase Ib/II clinical trial of its HIV-v vaccine which demonstrates a one log (approx 90 percent) difference in viral count in HIV-infected people compared with the placebo group, after just a single vaccine injection.

Gregory Stoloff, CEO of SEEK, commented: "This is the first time ever that an HIV vaccine has shown such a meaningful result in a human clinical trial. The next step will be to progress this to final human trials and determine the optimum dose and dosing regime to further enhance the vaccine's efficacy."

The development of an effective vaccine against HIV has been extremely difficult because the HIV virus constantly mutates. However, SEEK's HIV-v vaccine targets only the conserved regions in the internal proteins of the HIV virus which remain constant across all HIV strains. It is the first vaccine to generate both strong T-cell and antibody responses to eliminate HIV-infected cells and thus neutralise the HIV virus.  These unique features mean that the vaccine, while initially tested in an early stage of the disease as a therapeutic, could also be effective as a prophylactic, pending confirmation in a future trial.

Commenting on the results, Marta Boffito, MD, PhD, from the St. Stephen's Aids Trust and the principal investigator in the trial, said: "These are remarkable results which demonstrate HIV-v's safety and immunogenicity and, for the first time, a clinically relevant result,  as seen in the one log reduction in viral titres. HIV has long reached pandemic status and, despite growing numbers on anti-retrovirals, we are in desperate need of both a prophylactic and the
'/>"/>

SOURCE SEEK
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Biocept, Inc. Announces New CFO
2. Neogen Corporation Announces Year-End Results Conference Call
3. Elsevier Announces 2010 Journal Impact Factor Highlights
4. Summer Street Research Announces Expansion of Research Team with the Addition of Ling Wang, CFA, Senior Biotechnology Analyst
5. Oxygen Healthcare (O2h) Announces Expanded Chemistry Collaboration With Heptares Therapeutics
6. International Isotopes Inc. Announces the Selection of Parsons as the Lead Design-Build Contractor for the Proposed Depleted Uranium De-Conversion Facility
7. Emerson Ecologics Expands Partnership With Metagenics, Announces National Distribution Agreement
8. The J.R. Simplot Company Announces Innate™ All-Native Plant Technology
9. Trudeau Institute announces a discovery in the fight against sepsis
10. EffRx Announces Issuance of US Patent Providing Further Protection to EX101, Effervescent Alendronate Weekly Dosing Form
11. Generex Announces Publication of Studies with the Mayo Clinic Confirming and Extending the Antigen Express Ii-Key Platform Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Scottsdale, AZ (PRWEB) July 11, 2014 ... medicine device company specializing in the soft tissue ... SureLock All-Suture Anchor System for surgeries involving the ... predictable fixation through a novel, inserter-controlled deployment method. ... lead to partial deployment, anchor pull-out, or anchor ...
(Date:7/10/2014)... July 10, 2014 Deep Knowledge ... Medicine Forum on ‘Commercialising Longevity Research’ and welcomed ... to the London Bioscience Innovation Center for the ... and Aging Analytics Ltd. The meeting highlighted the ... translational research for age-related disease, as well as ...
(Date:7/10/2014)... Unraveling life’s mysteries can intrigue, amaze, and ... purchased a DNA test to unravel the ... a lifetime of memories, sharing, and closeness. In fact, ... genuinely brought the family closer together. , Recently, ... history and prior to taking the genetic ancestry ...
(Date:7/10/2014)... QC (PRWEB) July 10, 2014 EvoDerma ... and convenience. This rejuvenating device now comes with a second ... develops over time. , The new cup is thinner on ... design works to target rough, thin and uneven surfaces on ... firm cup for a stimulating treatment on areas such as ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 2DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 4DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 5DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 6Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2
... United,Therapeutics Corporation (Nasdaq: UTHR ) announced today ... results before market open on,Thursday, October 30, 2008., ... on Thursday,October 30, 2008, at 9:00 a.m. Eastern ... international callers dialing,1-706-679-8129. A rebroadcast of the teleconference ...
... Oct. 23 SuperGen, Inc.,(Nasdaq: SUPG ... discovery and,development of novel cancer therapies, today ... and four additional posters, at the 20th,EORTC-NCI-AACR ... in,Geneva, Switzerland. MP-470, an orally bio-available multi-targeted,tyrosine ...
... 2008) -- A study seeking possible cancer genes elucidated the ... form of lung cancer lung adenocarcinoma and could ... the Baylor College of Medicine Human Genome Sequencing Center that ... National Human Genome Research Institute. , In the report ...
Cached Biology Technology:SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy 2SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy 3SuperGen's MP-470 Demonstrates Clinical Tumor Regression When Combined with Standard of Care Chemotherapy 4Unraveling the genetic picture of lung cancer 2
(Date:7/11/2014)... fire started near the City of Entiat on Tuesday, ... the fire quickly grew to over 1,000 acres by ... fire is under investigation by the Washington Department of ... existing local resources in developing fire control strategies and ... Washington State Department of Natural Resources, (WA DNR), Bureau ...
(Date:7/11/2014)... a new professorship in tissue engineering to promote ... Engineering and the Marine Biological Laboratory, supported by ... Eugene Bell Foundation., The Eugene Bell Professorship in ... Molecular Engineering. That endowed chair holder also will ... Bell Center for Regenerative Biology and Tissue Engineering, ...
(Date:7/11/2014)... TRAP" to capture the early signs of kidney failure, ... Journal of Clinical Investigation . Their new transgenic ... cellular and genetic information from a variety of solid ... for Medical Research in 2008, TRAP involves attaching a ... the cell type of interest. Scientists can then collect ...
Breaking Biology News(10 mins):New professorship in tissue engineering links molecular engineering, marine biology 2
... 9, 2012) In a study to be presented today ... Meeting , in Dallas, Texas, researchers will report findings that ... rupture of membranes between the 34th and 37th week of ... risk of infection or respiratory problems in the newborn. ...
... Some unusual alliances are necessary for you to ... enable better treatment of neuromuscular diseases, such as myasthenia ... brain, said Dr. Lin Mei, Director of the Institute ... University. , During development, neurons in the spinal cord ...
... in rice grains conducted by researchers at the RIKEN ... 131 rice metabolites and clarified the genetic and environmental ... natural way to bioengineer improved rice grain varieties by ... value of crops. As one of the most ...
Cached Biology News:Study indicates that induced labor may not lower risk of infection or respiratory problems in newborns 2Unusual alliances enable movement 2New study sheds light on genetics of rice metabolism 2
... in an easy-to-use benchtop package. Our ... (ESI-oa-TOF) concentrates the performance of a ... fits on your bench. The microTOFLC ... FWHM and mass accuracy of better ...
... IndicationIncludes all the features of Tracker, plus software ... for a user defined period of time in ... a family of instruments all built around a ... and that can track two fields at once ...
... features of Tracker, plus software to note when ... provide a food reward.The Spatial Behavior line is ... video camera, frame grabber, and feature extraction software ... and up to 6 moving animals. Software ...
... Tracker, plus software to note when an animal ... arena, and trigger a penaltyThe Spatial Behavior line ... a video camera, frame grabber, and feature extraction ... once and up to 6 moving animals. ...
Biology Products: