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SAFC to Expand High-Potency API Fermentation Capabilities
Date:9/26/2007

consistent with SAFC's strategy to extend the range and scope of coverage in niche technologies and APIs for biologics sectors."

This planned expansion complements other recent St. Louis enhancements of SAFC Pharma's biotechnology facilities, including the 25,000 sq. ft. cGMP purification and manufacturing facility for transgenic plant and other non-animal derived protein drug substances and its segregated partner, the 6,000 sq. ft. purification suite for animal-derived proteins located in St. Louis, Missouri.

SAFC Pharma is focused on cGMP manufacturing, process development and contract services for small organic APIs and advanced intermediates, and the development of large molecule biopharmaceuticals.

About SAFC: SAFC(R) is the custom manufacturing and services group within Sigma-Aldrich that focuses on high-purity inorganics for high technology applications, cell culture products and services for biopharmaceutical manufacturing, biochemical production and the manufacturing of complex, multi-step organic synthesis of APIs and key intermediates. SAFC has manufacturing facilities around the world dedicated to providing manufacturing services for companies requiring a reliable partner to produce their custom manufactured materials. SAFC has four focus areas -- SAFC PharmaTM, SAFC Supply Solutions(R), SAFC BiosciencesTM, and SAFC HitechTM -- and had annual sales of nearly $500 million in 2006. SAFC is one of the world's 10 largest fine chemical businesses. For more information about SAFC visit http://www.safcglobal.com.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. We have customers in life science comp
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