Navigation Links
SAFC to Expand High-Potency API Fermentation Capabilities
Date:9/26/2007

$29 Million Expansion of Israel Manufacturing Site

ST. LOUIS, Sept. 26 /PRNewswire-FirstCall/ -- SAFC(R), a member of the Sigma-Aldrich(TM) Group (Nasdaq: SIAL), has announced a $29 million investment to significantly expand its drug substance capabilities in high-potency biologics at the Sigma-Aldrich facility in Jerusalem, Israel. The site enhancement will enable SAFC Pharma(TM) to provide process development and cGMP manufacturing to customers requiring large-scale, high-potency, toxic or hazardous drug substances (large molecule HPAPIs).

The biologics area exploits over 30 years of Sigma-Aldrich's expertise in research, development and scale-up of fermentation-derived products in Israel and close technology links to Israel's academic and R&D communities. Scheduled for completion in the first quarter of 2009, the 50,000 sq. ft. high-potency fermentation expansion will focus production on secondary metabolites (antibiotic-like molecules), cytotoxins and large-molecule proteins. A 30,000 sq. ft. area of the new facility has been designed to be Biosafety Level 2 compliant -- enabling manipulation of human pathogens. Site capabilities include 1,000 and 4,000-liter tank capacities for bacterial and fungal fermentation.

The new capabilities are expected to expand SAFC Pharma's High Potent Active Pharmaceutical Ingredient (HPAPI) offering to include fermentation-derived HPAPI manufacturing, complementing the multi-step organic synthesis flagship facility at its Madison, Wisconsin location.

Commenting on the investment, Frank Wicks, SAFC President, said, "This expansion builds on the fermentation track record of our Jerusalem facility while adding significantly to our HPAPI capacity. It is
'/>"/>

SOURCE Sigma-Aldrich
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Expand High FidelityPLUS PCR System
2. Expand High Fidelity PCR System
3. Expand 20 kbPLUS PCR System
4. Expand Long Template PCR System
5. Combine High Yield, Great Accuracy and the Prevention of Carry-over Contamination by Using the Novel Expand High FidelityPLUS PCR System
6. WARF expands license agreement with Advanced Cell Technology
7. Berbee to expand at New Venture Center
8. Verizon expands broadband service in Wisconsin
9. Bandwidth provider expands in Milwaukee
10. Johnson Controls to expand in Europe
11. Wisconsins biodiesel network expands
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... Albany, NewYork (PRWEB) September 01, 2014 ... Pharma, Biotech and Diagnostics report provides comprehensive understanding ... and agreements entered into by the worlds leading ... detailed understand and analysis of how and why ... flexibility of a prospective partner’s negotiated deals terms ...
(Date:8/31/2014)... 31, 2014 2014 Market ... a professional and in-depth research report on ... Polyacrylamide information, including Polyacrylamide definition, classification, application, ... industry overview. This research covers the international ... as global industry analysis covering macroeconomic environment ...
(Date:8/29/2014)... SAN DIEGO, Aug. 29, 2014  Pfenex Inc. ... in the development of high-value and difficult to ... business update and reported financial results for the ... "With the successful completion of our initial public ... advance our biosimilar product candidates, derived from our ...
(Date:8/29/2014)... According to a new market report published by Transparency ... valued at USD 3,754.6 million in 2012 and is estimated ... CAGR of 5.9% from 2013 to 2019. , Nearly half ... by bone and joint disorders, and this number is expected ... will continue to increase the demand for orthobiologics. Other factors ...
Breaking Biology Technology:Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 3Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 4International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 2International Polyacrylamide Industry & Copper Iodide Market Data Analysis Now Available at DeepResearchReports.com 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 2Pfenex Reports Second Quarter 2014 Results and Provides Business Update 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 4Pfenex Reports Second Quarter 2014 Results and Provides Business Update 5Pfenex Reports Second Quarter 2014 Results and Provides Business Update 6Pfenex Reports Second Quarter 2014 Results and Provides Business Update 7Pfenex Reports Second Quarter 2014 Results and Provides Business Update 8Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3
... Researcher Provides Extensive Experience In Molecular DiagnosticsSALT LAKE ... company revolutionizing spine care through the development of ... Macina, Ph.D., has joined the executive management team ... and Development. Dr. Macina will report directly to ...
... Feb. 24 Innovative Biosensors, Inc., and ProGenTech ... diagnostics, today announced an agreement to jointly develop ... incorporate Innovative Biosensor,s proprietary Cellular Analysis and Notification ... cell-based approach for quickly detecting various pathogens, into ...
... the gene that ultimately controls the production of tooth ... to the repair of damaged enamel, a new concept ... of replacement teeth. , The gene, called Ctip2, is ... several functions - in immune response, and the development ...
Cached Biology Technology:Axial Biotech Appoints Dr. Roberto Macina to Vice President of Research and Development 2Innovative Biosensors and ProGenTech Partner to Develop a Rapid Diagnostics System 2Innovative Biosensors and ProGenTech Partner to Develop a Rapid Diagnostics System 3Genetic discovery could lead to advances in dental treatment 2
(Date:9/2/2014)... September 2, 2014 A study published in ... of the American Academy of Child and Adolescent ... with a psychiatric diagnosis had an increased risk ... antipsychotics. , Using data from the nationwide Danish ... Ren Ernst Nielsen, Psychiatry, Aalborg University Hospital, Denmark, ...
(Date:9/2/2014)... of lithographic limestone is well known as a ... that area (for example, Archaeopteryx). Now, for the ... the French equivalent of these outcrops - discoveries ... known water treader. , Despite the abundance of ... have been obtained from the Late Kimmeridgian equivalents ...
(Date:9/1/2014)... in the U.S. has improved steadily in recent yearsspurred ... dietary quality remains poor and disparities continue to widen ... study from Harvard School of Public Health (HSPH). , ... that the extensive efforts by many groups and individuals ... but it also indicates that these efforts need to ...
Breaking Biology News(10 mins):Risk of diabetes in children and adolescents exposed to antipsychotics 2Exceptionally well preserved insect fossils from the Rhône Valley 2Quality of US diet shows modest improvement, but overall remains poor 2Quality of US diet shows modest improvement, but overall remains poor 3
... in German . It,s a quick process, ... seconds, a laser beam has welded the casing and speedometer cover ... is a perfect weld seam scarcely visible to the naked eye. ... welding. What,s more: the resulting heat is confined to a minimal ...
... Columbia have been able to pinpoint more of the ... valuable compounds to the roasting process. Lead author ... the prevailing antioxidants present in dark roasted coffee brew ... high temperatures. Their findings will appear in ...
... of Zaragoza (UNIZAR) has studied precipitation trends in Spain,s ... The results show that precipitation has declined overall between ... of the rainy season. The rains are heavier in ... ,Since 1946, the average precipitation falling on Spanish hydrological ...
Cached Biology News:Laser welding in the right light 2Roasting coffee beans a dark brown produces valued antioxidants: UBC food scientists 2Rain in Spain is on the decline 2
... designed to rapidly and reliably amplify unknown ... Technology. APAgene provides hassle-free, ready-to use components, ... ingredients are provided in each kit. The ... gap filling, localized cloning of genomic DNA, ...
No description available in Ensembl. Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Rabbit polyclonal to Yaf9 ( Abpromise for all tested applications)....
... is designed to deparaffinize and perform Heat ... paraffin-embedded tissue sections mounted on glass microscope ... paraffin at the high temperature used in ... of the paraffin by detergent. Formaldehyde fixation ...
Biology Products: