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SAFC Biosciences(R) Expands Media Capability for Chinese Hamster Ovary (CHO) Cell Lines
Date:4/8/2009

roduction to blockbuster therapeutic commercialization.

According to Mason Williams, SAFC Biosciences Product Manager, the Company is already seeing the early adoption of this new EX-CELL CD CHO Fusion formulation by some of the most significant companies in the Biopharmaceutical industry as a result of their participation in a beta-site testing program. "One early customer," says Williams, "has already requested larger quantities for projects in clinical process scale-up."

EX-CELL CD CHO Fusion is also featured in the new CHO cGMP Media Library, a robust collection that contains more than 20 cGMP media formulations for CHO cells that can be quickly accessed for media screening optimization projects.

Historical data shows that CHO clones have diverse nutritive requirements and that no single media formulation is optimized for every application. According to Archie Cullen, Vice President of Global Commercial and Technical Operations for SAFC Biosciences, "We have successfully developed a program that we believe efficiently allows clients to screen a robust offering of media formulations through the CHO Library to quickly identify the best starting point for every application, while also reducing concerns around scale-up by having the formulations already produced to cGMP. This capability demonstrates SAFC Biosciences' 'best fit' approach to providing solutions personalized to the specific requirements of our customers and their applications."

Cullen continued, "The next step in this approach is the launch of a Platform Chemically Defined Supplement that effectively removes the dependence on hydrolysates or other undefined components that have challenged production processes."

Further information on EX-CELL(TM) CD CHO Fusion and the CHO cGMP Media Library can be found at www.safcbiosciences
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SOURCE Sigma-Aldrich
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