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SAFC Biosciences(R) Defines Hydrolysate Components That Enhance Chinese Hamster Ovary (CHO) Cell Line Protein Production
Date:7/28/2009

s partnership of technology and expertise enabled SAFC Biosciences to develop the first known chemically defined hydrolysate replacement. Matt Caple, SAFC Biosciences Director of Cell Sciences and Development, states: "The capacity for hydrolysates to exert substantial positive impact on cell growth and/or protein production is well documented. But, the undefined and variable nature of these components still inhibits the pursuit of highly controlled and defined pharmaceutical production processes. EX-CELL CD Hydrolysate Fusion resolves this challenge by delivering a fully defined raw material."

Bruce Lehr, SAFC Biosciences Director of Marketing, states: "Raw material understanding and characterization is a leading concern for biopharmaceutical manufacturers interested in mitigating risk. They desire to mitigate supply risk and production variability stemming from the use of undefined or adulterated raw materials in their process. Control of this variable enables manufacturers to design quality into their process instead of testing for it at the end. EX-CELL CD Hydrolysate Fusion is proof that greater raw material definition is possible through advanced analytical techniques."

Further information on the EX-CELL CD Hydrolysate Fusion revolution can be found at (http://www.safcbiosciences.com/ChemicallyDefinedComponents)

About SAFC Biosciences: SAFC Biosciences is a leading provider of cell culture materials and development services for upstream and downstream processes in the biopharmaceutical industry. Providing an integrated services package in mammalian cell culture media development, along with analytical and regulatory support, SAFC Biosciences employs a wealth of industry experience and scienti
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SOURCE Sigma-Aldrich
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