Rosetta Genomics Selects PCR as Platform for its microRNA-based Diagnostics to be Launched in 2008, Licensed Nanogen's MGB Probe ...( First microRNA-based Diagnostic Test...)

First microRNA-based Diagnostic Tests are Expected to be Launched in 2008

and Will Incorporate Nanogen's MGB Probe Technology Rosetta Genomics Will use the Licensed Technology in its Custom Designed Real-Time PCR Diagnostic Assays That Allow for Sensitive Detection and

Quantification of microRNA in Tissues and Body Fluids

REHOVOT, Israel; NORTH BRUNSWICK, New Jersey, December 11 /PRNewswire-FirstCall/ -- Rosetta Genomics, Ltd. (NASDQ: ROSG) announced today it has selected the technological platform for its line of microRNA-based diagnostic products, the first of which are expected to launch in 2008. The company has licensed the MGB Probe technology from Nanogen, Inc. (NASDAQ: NGEN). The licensing deal will allow Rosetta Genomics to combine the technical performance advantages of Nanogen's MGB Probe technology with the Company's own proprietary microRNA biomarkers to create a line of quantitative real-time PCR diagnostic tests.

Leveraging microRNAs' strong tissue specificity and involvement in the regulation of a large number of human genes, Rosetta Genomics has identified specific microRNA signatures that it believes will allow for accurate diagnosis of various cancers.

The Company expects the following three tests to launch in 2008:

- Differentiating squamous from non squamous lung cancer - As current targeted therapy for lung cancer can cause hemorrhaging in squamous cell lung cancer patients, differentiating between the cancer types is critical. Rosetta Genomics has identified several microRNA biomarkers that may allow for sensitive and specific identification of squamous cell carcinoma.

- Differentiating mesothelioma from lung adenocarcinoma - Rosetta Genomics has identif
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