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Rosetta Genomics Announces Expansion of its MicroRNA Intellectual Property Estate
Date:4/28/2008

and to defend its patent portfolio against challenges from third parties; Rosetta's ability to obtain additional funding to support its business activities; Rosetta's dependence on third parties for development, manufacture, marketing, sales, and distribution of products; the successful development of Rosetta's product candidates, all of which are in early stages of development; obtaining regulatory approval for products; competition from others using technology similar to Rosetta's and others developing products for similar uses; Rosetta's dependence on collaborators; and Rosetta's short operating history; as well as those risks more fully discussed under "Key Information - Risk Factors" in Rosetta's Annual Report on Form 20-F for the year ended December 31, 2006 on file with the Securities and Exchange Commission. In addition, any forward-looking statements represent Rosetta's views only as of today and should not be relied upon as representing its views as of any subsequent date. Rosetta does not assume any obligation to update any forward-looking statements unless required by law.

Contact:

Media:

Rachel Spielman,

T: +1-212-583-2714,

E: media@rosettagenomics.com ;

Investors:

Ron Kamienchick,

T: +1-646-509-1893,

E: investors@rosettagenomics.com .


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4. Rosetta Genomics Reports Fourth-Quarter and Full-Year 2007 Financial Results
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6. Henry Ford Hospital and Rosetta Genomics to Develop MicroRNA-based Diagnostics for Brain Cancer
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