"The scientific efforts in Madison are complementary to those at our other global RNA sites," said Lou Renzetti, Ph.D., global head, RNA Therapeutics at Roche. "Our colleagues in Madison have a lot to offer in terms of their expertise, which will significantly help our drug development efforts."
"These new lab facilities underscore both our commitment to the innovative talents of the team here at Roche Madison as well as to our pledge to explore and harness the potential of RNA-based therapeutics for complex diseases that are difficult to treat," said Lee Babiss, Ph.D., global head, Pharma Research at Roche.
RNAi (RNA interference) is a revolution in biology, representing a breakthrough in understanding how genes are turned on and off in cells. Its discovery was awarded the Nobel Prize in October 2006. By harnessing the natural biological process of RNAi occurring in our cells, the creation of a major new class of medicines, known as RNAi therapeutics, is on the horizon. RNAi therapeutics targets the cause of diseases by potently silencing specific messenger RNAs (mRNAs), thereby preventing disease-causing proteins from being made. RNAi therapeutics has the potential to treat disease and help patients in a fundamentally new way.
About Roche Madison
Roche Madison Inc. is a leader in the fields of RNA interference and gene therapy, based upon its expertise in non-viral nucleic acid chemistry and delivery. Effective and safe siRNA delivery represents the primary bottleneck to achieving therapeutic success using RNA interference. The company's Dynamic PolyConjugates(TM) (DPC) technology is being refined as an enabling nanotechnology platform for siRNA therapeutics, which makes it possible to target previously undruggable targets and has great potential for many diseases. DPCs represent a first in class polymer-based nano
|SOURCE Roche Madison Inc.|
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