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RiboMed and Austrian Institute of Technology Partner on Epigenetic Tests for Early Lung Cancer Detection, Sub-typing and Drug Response
Date:6/13/2013

ef)">Abscription® (Abortive Transcription) for detection. It is the combination of these two technologies in MethylMeter® assays that allows RiboMed to quantitatively measure DNA methylation levels on multiple genes, even with small samples containing damaged DNA.

AIT’s detection and subtyping panel of DNA methylation biomarkers will be coupled with additional DNA methylation biomarkers being validated by RiboMed that will predict the probability of the patient’s response to the most common drugs used to treat lung cancer. “By coupling AIT’s diagnostic and subtyping biomarkers with other biomarkers that predict drug response, we will provide physicians with a single test with both diagnostic and theranostic information” noted RiboMed CEO Dr. Michelle Hanna. “The discovery and development of biomarkers tests for drug response is becoming an essential component of cancer treatment. We are very excited to partner with AIT to develop and commercialize this ground-breaking lung cancer test.” The test will be developed and offered through the CLIA-certified RiboMed Clinical Services Laboratory in Carlsbad, CA.

RiboMed’s proprietary MethylMeter® Abscription-based assays provide extremely sensitive, accurate and quantitative measurement of the extent of methylation of the regulatory regions of different genes. They work well in serum, saliva, sputum, urine and even with FFPE samples, making them the ideal choice for oncology-based clinical diagnostic, prognostic, and theranostic epigenetic tests. RiboMed’s first prognostic test for brain cancer, launched in 2012, quantitatively measures the methylation levels of 8 genes from very small slices of FFPE tumor tissue with extremely low failure rates, results t
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