Navigation Links
RiboMed and Austrian Institute of Technology Partner on Epigenetic Tests for Early Lung Cancer Detection, Sub-typing and Drug Response

Carslbad, California (PRWEB) June 13, 2013

RiboMed Biotechnologies, Inc. ( a company that develops epigenetic-based tests that provide improved cancer diagnosis and allow drug therapy to be personalized for the benefit of cancer patients, today announced that it has partnered with researchers at the Austrian Institute of Technology (AIT, Vienna) to commercialize their clinically validated lung cancer DNA methylation biomarkers. Lung cancer is the number-one cause of cancer deaths in both men and women in the U.S. and worldwide. The biomarkers will allow the early detection of lung cancer, as well as subtyping of non-small cell lung cancer (NSCLC) into Adenocarcinoma or Squamous Cell Carcinoma, which are treated with different drugs. This detection and subtyping panel will not only allow physicians to diagnose the disease earlier, but will ensure that the patient receives the drug treatment that is specific for their type of cancer.

Dr. Martin Weber, Business Unit Head Molecular Diagnostics at AIT, said “Teaming up our innovative lung cancer DNA-methylation biomarker sets with RiboMed’s leading technology for epigenetic diagnostic tests is an important milestone for AIT. In our view this agreement is a first step to a successful commercialization of our biomarkers together with a partner that perfectly complements our own core competencies”. RiboMed has developed both a proprietary affinity protein, MethylMagnet®, to separate methylated and unmethylated DNA and an extremely sensitive signal generation process, Abscription® (Abortive Transcription) for detection. It is the combination of these two technologies in MethylMeter® assays that allows RiboMed to quantitatively measure DNA methylation levels on multiple genes, even with small samples containing damaged DNA.

AIT’s detection and subtyping panel of DNA methylation biomarkers will be coupled with additional DNA methylation biomarkers being validated by RiboMed that will predict the probability of the patient’s response to the most common drugs used to treat lung cancer. “By coupling AIT’s diagnostic and subtyping biomarkers with other biomarkers that predict drug response, we will provide physicians with a single test with both diagnostic and theranostic information” noted RiboMed CEO Dr. Michelle Hanna. “The discovery and development of biomarkers tests for drug response is becoming an essential component of cancer treatment. We are very excited to partner with AIT to develop and commercialize this ground-breaking lung cancer test.” The test will be developed and offered through the CLIA-certified RiboMed Clinical Services Laboratory in Carlsbad, CA.

RiboMed’s proprietary MethylMeter® Abscription-based assays provide extremely sensitive, accurate and quantitative measurement of the extent of methylation of the regulatory regions of different genes. They work well in serum, saliva, sputum, urine and even with FFPE samples, making them the ideal choice for oncology-based clinical diagnostic, prognostic, and theranostic epigenetic tests. RiboMed’s first prognostic test for brain cancer, launched in 2012, quantitatively measures the methylation levels of 8 genes from very small slices of FFPE tumor tissue with extremely low failure rates, results that were unobtainable with conventional bisulfite-based PCR, enzymatic, and sequencing methods.

Survival rates for lung cancer are lower than those for most cancers, with an overall five-year survival rate of only 16% compared to 65% for colon cancer and over 99% for prostate cancer. In up to 25% of people who get lung cancer, the cancer is first discovered on a routine chest X-ray or CT scan as a small mass, by which time, the cancer has often spread. Earlier detection, coupled with information on the correct drug treatment would be a powerful life-saving tool for physicians.

About RiboMed: RiboMed Biotechnologies ( is a molecular diagnostic company with a focus on Epigenetic Diagnostics and Theranostics in Oncology. The Company develops and provides products, services, and tests for disease screening, diagnostics, theranostics, post-treatment monitoring, and drug development utilizing its proprietary and patented technology platforms for biomarker detection (Abscription) and methylated DNA isolation and quantification (MethylMagnet® and MethylMeter®). RiboMed Clinical Services Laboratory (RCSL), a fully compliant CLIA certified division, offers sensitive and quantitative DNA Methylation profiling clinical assay development services which provide reliable results even with FFPE tissues. RiboMed has over 10 issued patents for the use of Abscription for biomarker detection, including RNA, protein, SNPs and other DNA alterations in addition to DNA methylation.

About AIT: The Austrian Institute of Technology ( is Austria´s largest non-university research institute with a European format and takes an important role in the field of innovation. One of its research areas, Molecular Diagnostics, is focused on the identification of effective ways for early diagnosis of diabetes, cancer and types of fibrosis. AIT provides scientific support and technologies to national and international research partners.

For more information, contact:
Michelle Hanna, Ph.D.
CEO & Scientific Director

This press release contains forward-looking statements and estimates with respect to the anticipated future performance of RiboMed and the market in which it operates. Such statements and estimates are based on assumptions and assessments of known and unknown risks, uncertainties and other factors, which were deemed reasonable but may not prove to be correct. Actual events are difficult to predict, may depend upon factors that are beyond the Company’s control, and may turn out to be materially different. RiboMed expressly disclaims any obligation to update any such forward-looking statements in this release to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based unless required by law or regulation.

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. RiboMed Receives Three Additional Patents for Disease Diagnostics Methods
2. RiboMed Receives Three Additional Patents for Disease Diagnostics Methods
3. MedeAnalytics Introduces New Provider Engagement Solution at AHIP Institute 2013
4. Singer-Songwriter Edwin McCain to Headline Steadman Philippon Research Institute's 2013 Annual "Rock the Research" Fundraiser in Vail, Colorado
5. New York Blood Centers Research Institute Receives Grand Challenges Explorations Grant For Groundbreaking Research in Global Health and Development
6. Inflamax Research selected by the Immune Tolerance Network and the National Institutes of Health to conduct a landmark clinical study on the underlying mechanisms of allergic inflammation.
7. BioHealth Innovation, Inc. Names Ram Aiyar as Entrepreneur-in-Residence to NIH National Heart, Lung and Blood Institute
8. Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device
9. HealthSparq to Reveal New Healthcare Transparency Benchmark Study at AHIP Institute 2013
10. Director of Proteomics at the Broad Institute of MIT and Harvard, Steven Carr, to Deliver Pittcon 2014 Wallace H. Coulter Plenary Lecture
11. J. Craig Venter Institutes Mobile Genomics Lab Launches First School Visits in San Diego County
Post Your Comments:
(Date:6/24/2016)... NC (PRWEB) , ... June 24, 2016 , ... Researchers ... the most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are ... to read it now. , Diagnostic biomarkers are signposts in the blood, lung ...
(Date:6/23/2016)...   Boston Biomedical , an industry leader ... target cancer stemness pathways, announced that its lead ... Designation from the U.S. Food and Drug Administration ... gastroesophageal junction (GEJ) cancer. Napabucasin is an orally ... stemness pathways by targeting STAT3, and is currently ...
(Date:6/23/2016)... 23, 2016 Houston Methodist Willowbrook Hospital ... Sports Association to serve as their official health ... Methodist Willowbrook will provide sponsorship support, athletic training ... association coaches, volunteers, athletes and families. ... Sports Association and to bring Houston Methodist quality ...
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
Breaking Biology Technology:
(Date:6/2/2016)... Perimeter Surveillance & Detection Systems, Biometrics & ... & Other Service  The latest report from ... of the global Border Security market . Visiongain ... billion in 2016. Now: In November 2015 ... and hardware technologies for advanced video surveillance. ...
(Date:5/12/2016)... 2016 , a brand of ... results from the Q1 wave of its quarterly wearables ... consumers, receptivity to a program where they would receive ... insurance company. "We were surprised to see ... Michael LaColla , CEO of Troubadour Research, "primarily because ...
(Date:4/26/2016)... and LONDON , ... Finacle, part of EdgeVerve Systems, a product subsidiary ... Onegini today announced a partnership to integrate the ...      (Logo: ) ... provide their customers enhanced security to access and ...
Breaking Biology News(10 mins):