Navigation Links
Rib-X Pharmaceuticals Announces Positive Phase 2 Study Results for Delafloxacin and a $25 Million Financing
Date:1/26/2009

xacin is a novel, broad spectrum, next-generation fluoroquinolone, that is more active than other quinolones against Gram-positive bacteria, including isolates of MRSA that are resistant to other quinolones. In large panel microbiological testing, the compound has been shown to be at least 32-fold more potent than levofloxacin, ciprofloxacin, gatifloxacin and moxifloxacin against quinolone-resistant MRSA (MIC90 of less than or equal to 0.5 micrograms/mL for delafloxacin versus > 16 micrograms/mL for all other quinolones). Currently in development as an intravenous formulation, delafloxacin has also been shown to be more potent than existing quinolones against a range of Gram-positive, anaerobic and Gram-negative organisms. Rib-X is interested in developing both IV and oral formulations of delafloxacin for use in surgical prophylaxis and other therapeutic arenas within the over $9.9 billion hospital antibiotic market.(1)

About Rib-X Pharmaceuticals, Inc.

Rib-X Pharmaceuticals, Inc. is a product-driven small molecule drug discovery and development company focused on the structure-based design of new classes of antibiotics. The Company's underlying drug discovery engine capitalizes on its proprietary high-resolution crystal structure of the ribosome, which performs an essential role in protein synthesis. Many known, commercially valuable antibiotics exert their effects by binding to the bacterial ribosome. The Company's integrated research strategy, which combines state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibiotics that can be used for the treatment of either community- or hospital-acquired infections. In addition to delafloxacin, Rib-X is currently in Phase 2 tria
'/>"/>

SOURCE Rib-X Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Rib-X Pharmaceuticals to Present at the 2008 ICAAC/IDSA Joint Meeting
2. Rib-X Pharmaceuticals, Inc. Announces Formation of Clinical Advisory Board
3. Rib-X Pharmaceuticals to Present at Cambridge Healthtech Institutes 2nd Annual Challenge of Antibacterial Development Conference
4. Rib-X Pharmaceuticals Initiates Two Phase 2 Studies for Novel Antibiotic Compound RX-1741
5. MAP Pharmaceuticals Announces Completion of Enrollment in Phase 3 Clinical Trial of MAP0004 in Patients with Migraine
6. Axikin Pharmaceuticals Spins out of Actimis
7. BioMed Realty Trust Extends Leases With Vertex Pharmaceuticals Through 2015
8. Poniard Pharmaceuticals Announces Positive Tumor Response and Neuropathy Data from Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer
9. Cumberland Pharmaceuticals Appoints Lee Product Director
10. Genesis Pharmaceuticals Appoints KPMG to Help Develop a SOX 404 Compliance Program
11. Keryx Biopharmaceuticals to Present at the J.P. Morgan 27th Annual Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/14/2014)... when it comes to survival strategies. They often create ... for example during treatment with antibiotics. A biofilm is ... slime capsule consisting of sugar chains and "curli". ... the first time created a detailed three-dimensional image of ... the bacterial cell wall, a crucial step in the ...
(Date:9/12/2014)... magnet using an electric field (magnetoelectric memory [MEM] ... next-generation technology for information processing and storage. Multiferroic ... due to the coexistence of electric and magnetic ... spontaneous electric and magnetic polarizations is rare in ... the MEM effect. This article briefly reviews a ...
(Date:9/12/2014)... Advancing the front lines of ... and biological threats is the mission of an ... (WPI) and the Georgian National Academy of Sciences, ... and Security Programme of the North Atlantic Treaty ... Workshop series, the event is titled “Nanotechnology to ...
(Date:9/12/2014)... Mountain View, CA (PRWEB) September 12, 2014 ... its fundraising campaign on Indiegogo. , The film, ... Stephen Hawking, Buzz Aldrin, Shimon Peres, Ashton Kutcher, Will.i.Am, ... changing the world and there’s only one university in ... it to help change the lives of a billion ...
Breaking Biology Technology:New insights in survival strategies of bacteria 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 3Documentary Film that Follows Singularity University Students as They Change the World Launches its IndieGoGo Fundraising Campaign 2
... , , , , , , ... Amex: NBS ) ("NeoStem" or the "Company"), an international,biopharmaceutical company ... it priced a public offering of 5,000,000 shares of its common ... after underwriting,discounts and commissions and expenses, will be approximately $5,697,500 ...
... , , , SHENYANG, ... Inc. (Nasdaq:, SSRX ) ("3SBio" or "the Company"), a ... manufacturing and marketing,biopharmaceutical products, and Ascentage Pharma Group Corporation, ... strategic,alliance to research, develop and commercialize best-in-class targeted cancer,therapeutics ...
... simple one-step process that produces both n-type and ... use of the promising material for future electronic ... used to increase conductivity in graphene nanoribbons used ... (SOG) material to graphene and then exposing it ...
Cached Biology Technology:NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 2NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 3NeoStem Prices Public Offering of 5,000,000 Shares of Common Stock 43SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 23SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 33SBio and Ascentage Pharma Form Strategic Alliance to Research, Develop and Commercialize Cancer Therapeutics 4Single-step technique produces both p-type and n-type doping for future graphene devices 2Single-step technique produces both p-type and n-type doping for future graphene devices 3
(Date:9/15/2014)... the Department of Science and Technology in Society in ... Virginia Tech, has won a 2014 National Science Foundation ... and problems of creating a global nuclear emergency response ... Nuclear Power Plant in March 2011 was a turning ... Schmid said. Three of the plant,s six nuclear reactors ...
(Date:9/15/2014)... of the cheetah: The big predator is the fastest land ... just a few seconds. As it ramps up to top ... it reaches a full gallop. , Now MIT researchers have ... a robotic cheetah a sleek, four-legged assemblage of gears, ... its feline counterpart. The team recently took the robot for ...
(Date:9/15/2014)... no published account where hippopotamuses are demonstrably shown swimming ... water. But if they can,t swim, how did they ... accepted models for the methods, patterns, and timing of ... Crete, and Madagascar) may need to be reconsidered. , ... mainland are not currently supported by positive geological ...
Breaking Biology News(10 mins):'Nuclear disasters don't respect national boundaries' 2Run, cheetah, run 2Run, cheetah, run 3
... shift away from traditional coffee-growing techniques may be increasing ... that has swept through plantations in Central America and ... studies the disease. The current outbreak of coffee ... Mexico since the fungal disease arrived in the region ...
... stations could be drastically reduced by a new, energy-efficient ... releases it when exposed to sunlight. In a ... University and CSIRO scientists for the first time discovered ... of materials known for their exceptional capacity to store ...
... African-American women battling vitamin D deficiencies need the same ... to a recent study accepted for publication in The ... (JCEM). Although women with darker skin tones ... to measure Vitamin D levels, called 25-hydroxyvitamin D or ...
Cached Biology News:Modern growing methods may be culprit of 'coffee rust' fungal outbreak 2Modern growing methods may be culprit of 'coffee rust' fungal outbreak 3Carbon sponge could soak up coal emissions 2African-American, Caucasian women should take identical vitamin D doses 2