Navigation Links
Revised: Othera Pharmaceuticals Appoints Dr. Frederick R. Rickles Chief Scientific Officer
Date:10/2/2007

EXTON, Pa., Oct. 2 /PRNewswire/ -- Othera Pharmaceuticals, Inc., a specialty pharmaceuticals company focused on novel, patient-administered products for ophthalmology, oncology, and inflammatory disease, has announced the appointment of Frederick R. Rickles, MD, FACP, as Chief Scientific Officer effective immediately. In this position, Dr. Rickles will lead the development, integration and execution of Othera's research and clinical development programs.

"We are delighted to welcome Dr. Rickles to the Othera team," said David Joseph, Chairman and CEO of Othera Pharmaceuticals, Inc. "His broad expertise in oncology, hematology (thrombosis), and pharmacology will serve Othera well as we pursue our goal of becoming a leading specialty pharmaceutical company. Othera's business strategy requires an important focus on product diversification and target selection, and, thus, we will benefit from his extensive background and expertise."

Commenting on his new position, Rickles said, "This is an outstanding opportunity to join a specialty pharmaceutical company at a very important strategic stage of the organization. I believe that Othera's novel molecules and extensive intellectual property gives us the flexibility to build our future portfolio and create a broad growth platform, and I am delighted to have a key role in that effort."

Rickles, a 37-year veteran of the Medical Community, presently serves as a Fellow in the Center for Science and Technology, Healthcare Division of Noblis, a non-profit organization that works in the public interest. Among other important healthcare projects, Noblis helped the Centers for Medicare and Medicaid Services (CMS) implement Medicare Part D. Dr. Rickles has been working on a number of healthcare policy issues for Noblis, including pharmacovigilance, with a consortium of public and private stakeholders. Additionally, he has served as Associate VP/Health Research at The George Washington University (GWU) and was the CEO and Executive Director of the Federation of American Societies for Experimental Biology (FASEB), a coalition of 21 leading life science research organizations. He also served as a scientific advisor for multiple leading pharmaceutical and private sector companies and such as Pfizer and Caremark, respectively.

Rickles is a graduate of the University of Illinois College of Medicine and trained in internal medicine and hematology at the University of Rochester/Strong Memorial Hospital. He will continue to serve as a Professor of Medicine in the Division of Hematology-Oncology, Department of Medicine at GWU. He will also maintain his position as a teaching attending physician at the GWU Hospital in Washington, DC. Rickles will also continue to serve as member of multiple editorial boards, medical association committees, and scientific advisory boards.

About Othera Pharmaceuticals

Founded in 2002, Othera Pharmaceuticals, Inc. is a specialty pharmaceutical company focused on developing novel, patient-administered products for ophthalmology, oncology, and inflammatory diseases.

Othera's most advanced product is currently in Phase 2 clinical trials for the treatment of major age-related macular degeneration (AMD). OT-551 is a novel small molecule that inhibits oxidative stress and disease-induced inflammatory responses that contribute to loss of vision in AMD patients. "OT-551 is topically dosed in an eye drop and has the unique ability to penetrate cell membranes and reach both the front and the back of the eye," said David S. Joseph, chairman and CEO of Othera Pharmaceuticals. "We are very encouraged by preclinical research results demonstrating that OT-551 may be the first drug treatment for both the dry and wet form of age-related macular degeneration (AMD). Two Phase 2 trials of OT-551 in AMD patients are currently underway with initial results expected in 2008."

In addition to its lead compound, OT-551, Othera is also developing OT-730 as a novel improved beta-blocker for treatment of glaucoma. OT-730 is designed to have excellent beta-blocking activity in the eye, yet easily break down into inert components upon entry into the bloodstream. Today's marketed beta-blockers as a class are the most widely-prescribed drugs by volume for glaucoma, but suffer from the potential danger of systemic side effects. Initial preclinical studies support the concept that OT-730 could overcome the systemic side effect problem. An IND filing is planned for 2008.

Othera's product pipeline also includes orally-acting, small molecule analogues of OT-551. OT-304 has been identified as the lead candidate in this series and has demonstrated activity in preclinical models of cell-mediated thrombosis in cancer and inflammatory diseases. Completion of preclinical development supporting the use of OT-304 in the treatment and/or prevention of thrombosis in cancer and inflammatory diseases is expected later this year. The appointment of Dr. Rickles as CSO will enhance Othera's existing development capabilities and expertise as he is one of the most recognized experts in cancer and thrombosis in the world.

For information please visit Othera's website at http://www.othera.com.


'/>"/>
SOURCE Othera Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Related biology technology :

1. TomoTherapy reports 86% revenue jump, $131M net loss in Q1
2. TomoTherapy opens technical training center
3. TomoTherapy raises $223 million in IPO
4. TomoTherapy revises IPO money target
5. Hospital named for Madame Curie installs TomoTherapy system
6. TomoTherapy files registration statement for IPO
7. TomoTherapy to sell medical devices in India
8. TomoTherapy sees sustained market advantage
9. TomoTherapys 100th radiology system reaches public sector
10. TomoTherapy extends reach to Germany
11. Cash-rich TomoTherapy has no plans for IPO
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... India , January 24, 2017 According to ... Culture, Cell Expansion, Cell Counting, Cell Line Development, Flow Cytometry, Single-Use Bioprocessing, ... to 2021", published by MarketsandMarkets, the global market is expected to reach ... a CAGR of 12.4% from 2016 to 2021. ... ...
(Date:1/24/2017)... Calif. , Jan. 24, 2017  Asterias ... pioneering the field of regenerative medicine, today announced ... Phase 1/2a clinical trial that showed additional motor ... of 10 million AST-OPC1 cells in AIS-A patients ... "Recovery of upper extremity motor function is ...
(Date:1/24/2017)... ... January 24, 2017 , ... Nanomedical ... assays for fragment-based screening, will showcase its proprietary Field Effect Biosensing ... and Screening (SLAS) conference in Washington, D.C. from Feb. 6 to Feb. 8. ...
(Date:1/24/2017)... , ... January 23, 2017 , ... ... supports innovative science through unique partnerships, seeks outstanding early career nominees for the ... is critical to meeting the needs of a world in which one in ...
Breaking Biology Technology:
(Date:12/22/2016)... NEW YORK , December 22, 2016 ... global provider of secure solutions for the e-Government, Public Safety, HealthCare, ... a subsidiary of SuperCom, has been selected to implement and deploy ... county in Northern California , further expanding its ... ...
(Date:12/19/2016)... , 19 de diciembre de 2016  Mosaic Biomedicals SL ... desarrollo acelerado de MSC-1, un anticuerpo humanizado que se espera comenzar ... 2017, con múltiples sitios previstos a lo largo de Europa y ... MSC-1 es ... inhibidor de leucemia (LIF), una citoquina pleiotrópica que se sobreexpresa en ...
(Date:12/16/2016)... The global wearable medical device market, in terms of value, is ... billion in 2016, at a CAGR of 18.0% during the forecast ... Growth ... devices, launch of a growing number of smartphone-based healthcare apps compatible ... and increasing focus on physical fitness. Furthermore, growing ...
Breaking Biology News(10 mins):