Navigation Links
Retrospective Analysis of Phase 3 Data Suggest Wyeth's Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms
Date:9/25/2008

Separate Retrospective Analysis of Phase 3 Data Offers Additional Information on Bazedoxifene Alone

COLLEGEVILLE, Pa., Sept. 25 /PRNewswire/ -- A retrospective analysis of Phase 3 two-year data presented at the annual meeting of the North American Menopause Society (NAMS) suggest that postmenopausal women treated with bazedoxifene/conjugated estrogens (BZA/CE) may experience incidence of breast tenderness and abnormal mammograms no greater than those treated with placebo. BZA/CE is an investigational compound being studied by Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), for the treatment of moderate-to-severe menopausal vasomotor symptoms such as hot flashes and night sweats, and for the prevention of postmenopausal osteoporosis. Wyeth describes this compound as a tissue selective estrogen complex (TSEC).

In a retrospective analysis of data from another phase 3 study, treatment with Wyeth's investigational compound bazedoxifene (BZA) alone did not appear to increase mammographic breast density in postmenopausal women with osteoporosis compared to raloxifene (the active comparator) or placebo over two years. BZA is an investigational selective estrogen receptor modulator (SERM) under development for the treatment and prevention of postmenopausal osteoporosis.

Data Highlights

NAMS Poster Titled: Breast Effects of Bazedoxifene/Conjugated Estrogens in a Randomized, Controlled Trial of Postmenopausal Women

In the phase 3 study involving 3,397 postmenopausal women, primarily designed to evaluate the effects of BZA/CE on the endometrium and bone mineral density, mammograms were taken at baseline, and again at years one and two as part of the safety evaluation. Breast tenderness was reported in daily d
'/>"/>

SOURCE Wyeth Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. BioNanomatrix Announces Issuance of Key Nanofluidics Patent Enabling Single Molecule Whole Genome Analysis
2. SeqWright Unveils ABI SOLiD(TM) Next Generation Genetic Analysis System
3. Topline Findings from Comparative Analysis of INVEGA(TM) and Quetiapine in Schizophrenia to be Postered at the 20th Annual U.S. Psychiatric and Mental Health Congress
4. Massive reanalysis of genome data solves case of the lethal genes
5. ARRIVE Registry Analysis Demonstrates Continued Safety and Efficacy of TAXUS(R) Stent in Complex Real-World Patients
6. Gene Codes Corporation Announces Version 4.8 of Sequencher Software for DNA Sequence Assembly & Analysis
7. Pharsights Reporting and Analysis Services Business Reaches Quality Assurance Milestone
8. Center for Molecular Medicine Selected to Provide DNA Analysis for Childrens Oncology Group Leukemia Study
9. Credit-card-sized platform for volatile compound analysis CAREER project goal
10. New Glycobiology Analysis Manual 2nd Edition Provides Valuable Resource for Novices and Experts in the Field
11. Pharsights Reporting and Analysis Services Business Unit to Leverage New Validated Data Management System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... May 28, 2015 ... announced the addition of Jain PharmaBiotech,s new ... Markets, and Companies" to their offering. ... This report deals with therapeutic drug ... improving patient care by monitoring drug levels ...
(Date:5/28/2015)... DUBLIN , May 27, 2015 Research ... the "Animal Genetics Market by Products, by Testing ... their offering. The global animal genetics market ... 2014 and grow at a CAGR of 8-9% during ... This market is mainly driven by increasing animal protein ...
(Date:5/28/2015)... -- Celsion Corporation (the "Company") (NASDAQ: CLSN ) ... institutional healthcare investors to purchase an aggregate of approximately ... at-the-market registered direct offering and a concurrent private placement ... Company entered into a definitive purchase agreement with these ... an aggregate of 3,000,000 shares of its common stock ...
(Date:5/28/2015)... 2015  PDS Biotechnology Corp. announces preliminary data ... HPV-16, has generated strong T-cell responses in pre-cervical ... is treated by surgical removal of lesions however, ... alternative. Results show that it primes and activates ... and kill precancerous and cancerous cells that display ...
Breaking Biology Technology:Global Therapeutic Drug Monitoring Market 2015-2024 2Global Animal Genetics (Canine, Equine, Poultry, Porcine, Bovine, and Genetic Material) Market 2015 - Global Forecast to 2020 2Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 3PDS Biotechnology reports positive Phase I clinical trial results in proprietary HPV-Cancer Immunotherapy 2
... ... work based on data collected at the U.S. Department of Energy,s (DOE) Argonne National Laboratory. ... Argonne, Ill. (Vocus) ... award-winning work based on data collected at the U.S. Department of Energy,s (DOE) Argonne National ...
... Today the National Collegiate Inventors and Innovators Alliance ... recognizing undergraduate excellence in biomedical innovation. BMEStart stands ... because of its focus on younger inventors who ... development. , The BMEStart competition welcomes submissions ...
... Brad Thompson, President and CEO of Oncolytics Biotech Inc. ... corporate overview of the Company at the 17th Annual ... 12 at 10:15 a.m. The conference is taking place ... 11-13, 2009. , About Oncolytics Biotech Inc. , Oncolytics ...
Cached Biology Technology:Argonne's Advanced Photon Source Lit the Way to Chemistry Nobel 2Argonne's Advanced Photon Source Lit the Way to Chemistry Nobel 3NCIIA Announces New Undergraduate Competition 2Media Advisory - Oncolytics Biotech(R) Inc. to Present at BioPartnering Europe 2
(Date:5/21/2015)... -- The Sync Project™ , a global collaboration ... announced a collaborative partnership with Berklee,s Institute for ... collaboration on original research, joint course development and an ... The Sync Project and BerkleeICE are exploring the launch ... 2015-2016 academic year.  The course will ...
(Date:5/19/2015)... May 19, 2015 ... the addition of the  "Genetic Testing Market ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,A recent report, Genetic ... analysis of the current and future genetic ... tests, their working principles and types are ...
(Date:5/11/2015)...  Through a well-rounded UAS delegation representing private industry, government, ... showing at AUVSI,s Unmanned 2015 conference last week in ... UAS industry met with over 200 hundred people ... the UAS ecosystem. "Our message is clear ... Aerospace Rich Knoll . "If you want to fly ...
Breaking Biology News(10 mins):The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 2The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 3Global Genetic Testing Market Outlook 2018 2Ohio Flies High at Unmanned '15, Sets Stage for Ohio UAS Conference 2
... costs associated with storing nuclear waste and the possibility ... they may no longer be obstacles on the road ... at the University of Notre Dame, led by Thomas ... and concurrent professor of chemistry and biochemistry, showcases Notre ...
... the University of Melbourne have identified a new way ... hoped the test would be more cost effective and ... allergy in the community. Currently, an ... allergy, and while an oral food challenge is definitive ...
... A personality profile marked by overly gregarious yet anxious ... buried deep in the front center of the brain, say ... different types of brain imaging to pinpoint the suspect brain ... characterized by these behaviors. Matching the scans to scores ...
Cached Biology News:New paper by Notre Dame researchers describes method for cleaning up nuclear waste 2Test to improve peanut allergy diagnosis 2Friendly to a fault, yet tense: Personality traits traced in brain 2Friendly to a fault, yet tense: Personality traits traced in brain 3
...
...
... and anti-viral agent. Inhibits several important steps of ... of HUVEC cells. Also reduces intracellular reactive oxygen ... release of endothelial cells. Formula: ... O 8 MolWeight: ...
22 x 50 mm; No. 1 thickness range: 0.13 to 0.17 mm, suitable for work in histology, cytology, urinalysis and microbiology, precleaned, store at room temperature ...
Biology Products: