Navigation Links
Rethinking bacterial persistence
Date:1/3/2013

ent that persistent bacteria are those that have stopped growing and dividing. "We were able to reveal the role of an enzyme whose presence is necessary in order for the antibiotic to work, and show that the bacilli produced this enzyme in a pulsatile and random manner," explains Dhar. "Our measurements showed that bacterial death correlated more closely with the expression of this enzyme than with their growth factor." The research is being published this week in Science magazine.

These conclusions could mark the beginning of a new theory of bacterial resistance, or perhaps even introduce a new view of how such resistance evolves. Further research is being done using other microorganisms, such as tuberculosis and E. coli bacteria. The persistence of some cancer cells to treatment could also be studied in a different manner. "It's a new approach for trying to figure out why some infections are so difficult to eliminate. The techniques we've developed for this study are now also being used to develop new antibiotics, in collaboration with pharmaceutical companies," says McKinney, adding that "it is the microengineering expertise at EPFL that has enabled us to create these innovative tools and open up new avenues for investigation."


'/>"/>

Contact: Emmanuel Barraud
emmanuel.barraud@epfl.ch
41-796-283-642
Ecole Polytechnique Fdrale de Lausanne
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Sheffield scientists shine a light on the detection of bacterial infection
2. Bacterial protein mops up viruses found in contaminated water supplies
3. Scientists Discover How a Bacterial Pathogen Breaks Down Barriers to Enter and Infect Cells
4. Targeted antibacterial agent rapidly created in response to serious food safety pathogen
5. Scientists target bacterial transfer of resistance genes
6. Bacterial DNA sequence used to map an infection outbreak
7. PathoGenetix Names Ann Merrifield as Chief Executive Officer and Prepares to Launch Unique Bacterial Identification Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)...  BioSpecifics Technologies Corp. (NASDAQ: BSTC ... collagenase-based products marketed as XIAFLEX ® (collagenase ... XIAPEX ® in the EU, today announced ... Phase 2a study of CCH for the potential ... results showed that all three doses of CCH ...
(Date:8/21/2014)... Institute for Molecular Medicine Finland (FIMM), University of ... novel "man and machine" decision support system for ... described in PLOS One scientific journal ... computer vision algorithms similar to those used in ... the diagnostically most relevant areas. Tablet computers can ...
(Date:8/21/2014)... 21, 2014 2014 Deep ... is a professional and in-depth research report ... provides basic Seaweed Fertilizer information, including Seaweed ... structure as well as industry overview. This ... domestic market as well as global industry ...
(Date:8/21/2014)... Emmetsburg, IA (PRWEB) August 21, 2014 ... Project LIBERTY Opening , The Court of His Majesty ... King will attend the Grand Opening of POET-DSM Advanced ... on Wednesday, Sept. 3. , The King will take ... formal opening activity, scheduled for 11 a.m.-12:20 p.m. and ...
Breaking Biology Technology:BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5A novel 'man and machine' decision support system makes malaria diagnostics more effective 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 2Internationals Seaweed Fertilizer Industry 2014 Development Trend Analysis in New Research Study at DeepResearchReports.com 3His Majesty Willem-Alexander, King of the Netherlands, to Attend Project LIBERTY opening 2His Majesty Willem-Alexander, King of the Netherlands, to Attend Project LIBERTY opening 3
... Commission,s Joint Research Centre (JRC) has just launched ... representative range of 25 different types of reference ... consumer protection and confidence in many innovative applications ... promising technological developments. By enabling a harmonised risk ...
... CANTEL MEDICAL CORP. (NYSE: CMN ), through ... prevention and control business by purchasing the sterilization monitoring ... Colorado, ConFirm is one of the leading providers of ... ConFirm offers both a mail-in service and in-office spore ...
... LONG BRANCH, N.J., Feb. 14, 2011 Pharma ChemOutsourcing ... the first wave of 50 speakers from a diverse ...   "The biotechs all have clinical ... limited capital and human resources demonstrate how they have ...
Cached Biology Technology:Small material, big impact 2Cantel Medical Acquires the Sterilization Monitoring Business of ConFirm Monitoring Systems, Inc. 2Cantel Medical Acquires the Sterilization Monitoring Business of ConFirm Monitoring Systems, Inc. 3Pharma ChemOutsourcing 2011 Unveils First Wave of 50 Biotech Chemist Speakers for September 12-15 Show in New Jersey 2
(Date:8/21/2014)... to ignore, but they are the ultimate source of ... are increasingly dependent on algae, too, to suck up ... to the bottom of the ocean. Now, by using ... have evidence showing that viruses infecting those algae are ... when all else stays essentially the same, and this ...
(Date:8/21/2014)... Nine researchers from Beth Israel Deaconess Medical Center (BIDMC ... World,s Most Influential Scientific Minds 2014," a comprehensive ... a web resource for science metrics and research performance ... the most influential "are performing and publishing work that ... their science," according to a Thomson Reuters statement. Researchers ...
(Date:8/21/2014)... to Wednesday, Oct. 18-22, 2014 , WHERE: ... Drive, San Diego, CA 92101 , WHAT: ... presentations of the latest research in human genetics. ... featuring high-scoring abstracts on rare genetic variants in ... and treatment for sun sensitivity (Saturday, Oct. 18, ...
Breaking Biology News(10 mins):Viruses take down massive algal blooms, with big implications for climate 2BIDMC researchers named among 'the most influential scientific minds' 2BIDMC researchers named among 'the most influential scientific minds' 3American Society of Human Genetics 2014 Annual Meeting 2
... antibiotic appears to be a safe treatment for stroke and ... is currently the only FDA-approved drug therapy, researchers report. ... and Oregon found the drug well tolerated even at three-and-one-half ... arthritis, according to a research team led by the Medical ...
... flowers to produce pretty petals or sweet scents now ... new types of flowers. DNA analysis of wild evergreen ... of the plant could be derived from hybrids cross-breeds ... the rich biodiversity of the natural world, as it shows ...
... carbon nanotubes (hollow tubes of carbon atoms), MIT chemical ... 100 times more than a regular photovoltaic cell. Such ... energy, potentially allowing much smaller and more powerful solar ... a photovoltaic cell, you could have little spots that ...
Cached Biology News:Antibiotic appears safe for stroke patients and good companion for tPA 2Antibiotic appears safe for stroke patients and good companion for tPA 3Nature's gift for gardening may hold key to biodiversity 2MIT researchers develop a way to funnel solar energy 2MIT researchers develop a way to funnel solar energy 3