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Results of Court Meeting and Extraordinary General Meeting - Shareholders Approve Scheme of Arrangement and New Share Plans
Date:5/9/2008

y votes received for the EGM are set out below:

Resolution: For* Against Votes

withheld**

1. To approve the scheme of 327,897,582 1,186,103 685,056

arrangement and other

related matters (99.64%) (0.36%)

2. To approve the reduction 328,989,164 724,043 55,534

of capital of Shire

Limited (99.78%) (0.22%)

3. To approve the adoption 328,193,037 1,511,376 64,328

by Shire Limited of the

Shire Sharesave Scheme (99.54%) (0.46%)

and to approve the

authorisation given to

the directors of Shire

Limited in relation

thereto

4. To approve the adoption 328,231,073 1,474,257 63,411

by Shire Limited of the

Shire Employee Stock (99.55%) (0.45%)

Purchase Plan

5. To approve the adoption 288,944,476 38,538,346 2,285,919

by Shire Limited of Part

A of the Shire Portfolio (88.23%) (11.77%)

Share Plan

6. To approve the adoption 288,937,726 40,743,201 87,814

by Shire Limited of Part

B of the Shire Portfolio (87.64%) (12.36%)

Share Plan

* These figures include discretionary votes. **Votes withheld are not counted in the proportion of votes "for" or "against".

Copies of the resolutions passed at the Court meeting and the EGM have been submitted to the UKLA and are available for inspection at the UKLA's Document Viewing Facility, which is situated at the Financial Services Authority, 25 The North Colonnade, Canary Wharf, London E14 5HS.

Notes to editors

SHIRE PLC

Shire's strategic goal is to become t
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SOURCE Shire PLC
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