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Researchers visualize herpes virus' tactical maneuver
Date:1/6/2011

protein, the team has uncovered the mechanism by which the viral and cellular proteins work together to guide the viral genetic material out of the cell's nucleus. Once there, the genetic material can be utilized to make proteins that are used as building blocks for new viruses. The researchers have also confirmed that this relationship between the two proteins exists for related herpes viruses that infect monkeys.

Dr Golovanov continued "Our discovery gives us a whole step more detail on how herpes viruses use the human cell to survive and replicate. This opens up the possibilities for asking new questions about how to prevent or treat the diseases they cause."

Professor Janet Allen, BBSRC Director of Research said "This new research gives us an important piece of the jigsaw for how a particular viral infection works on a molecular level, which is great news. Understanding the relationship between a human, animal or plant the host and the organisms that cause disease pathogens is a fundamental step toward successful strategies to minimise the impact of infection. To study host-pathogen relationships we have to look in detail at the smallest scale of molecules as this study does and also right through to the largest scale of how diseases work in whole systems a crop disease in the context of a whole area of agricultural land, for example. BBSRC's broad portfolio of research into host-pathogen relationships facilitates this well."


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Contact: Nancy Mendoza
press.office@bbsrc.ac.uk
44-179-341-3355
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

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