Navigation Links
Researchers use magnetism to target cells to animal arteries
Date:1/7/2008

live. After introducing stainless steel stents into rats carotid arteries, Levys team used magnetic fields to steer the cells into the stents.

Patients with heart disease commonly receive metal stents in partially blocked blood vessels to improve blood flow, both by widening the vessels and delivering drugs. However, many stents fail over time as smooth muscle cells accumulate excessively on their surfaces and create new blockages. One goal of cell therapy is to introduce new endothelial cells to recoat stents with a smooth surface.

Furthermore, Levy adds, while drug-releasing stents currently provide benefits in treating diseased coronary arteries, they have proved far less effective in treating peripheral vascular disease, such as that occurring in patients with diabetes. In such cases, severe problems in blood circulation may force doctors to amputate a leg. In upcoming animal studies, Levys team will use their delivery approach to deliver magnetic nanoparticles to peripheral arteries.

Future studies, Levy added, also will use cells derived from the animal itself, to avoid potential rejection problems that may occur with unmatched cells. The current study used unmatched cells, delivering bovine cells to rat arteries, but only over a 48-hour period, too brief for rejection to occur.

The current study builds on research published earlier this year by Levy and collaborators, in which they used magnetic fields and nanoparticles to deliver DNA to arterial muscle cells in culture. That research focused on a delivery system for gene therapy, while the current study represents cell therapy. Levy suggests future applications may combine both therapies, using endothelial cells to deliver beneficial genes to damaged arteries.

The delivery system, says Levy, might also be applied to other sites where physicians implant steel stents to deliver medication, such as the esophagus, bile ducts and lungs. Another potential use might be
'/>"/>

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Ames Laboratory researchers solve fuel-cell membrane structure conundrum
2. Researchers outline structure of largest nonvirus particle ever crystallized
3. UD researchers race ahead with latest spintronics achievement
4. ASU researchers improve memory devices using nanotech
5. Researchers underscore limitations of genetic ancestry tests
6. Researchers measure carbon nanotube interaction
7. Stevens researchers provide new information about mass spectrometry
8. CU researchers shed light on light-emitting nanodevice
9. Long-awaited international ethical guidelines for biobank researchers
10. Researchers improve ability to write and store information on electronic devices
11. Sirnaomics Received Multiple Government Fundings For Its Multi-Targeted siRNA Therapeutics Programs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers use magnetism to target cells to animal arteries
(Date:11/21/2014)... The science of light and how ... more than 200 primary students in a traveling program ... of Otago Physics Department and funded by an ... of the university’s OSA/SPIE Student Chapter visited six primary ... children from small, rural schools hands-on lessons in optics ...
(Date:11/21/2014)... Los Angeles, CA (PRWEB) November 20, 2014 ... “A Short Walk to the Other Side” ... was an “Award-Winning Finalist in the “Fiction: Short Story” ... . , Jeffrey Keen, President and CEO of USA ... entries from mainstream and independent publishers, including Simon & ...
(Date:11/21/2014)... 2014 The report, "Synthetic ... Enzymes, Cloning kits), Technology (Bioinformatics, Nanotechnology, Gene ... Biomaterials, Bioremediation) - Global Forecast to 2018", ... threats, opportunities, and challenges. , Browse 99 ... through 185 pages and in-depth TOC of ...
(Date:11/21/2014)... 2014 BlueInGreen, LLC ( BlueInGreen® ... (Pinnacle), and PCI, Inc., leading suppliers of ozone ... been selected to provide a new state-of-the-art ozone ... R. Noland Wastewater Treatment. The new ozone ... gas dissolution technology, Pinnacle Ozone’s industry leading ...
Breaking Biology Technology:Optics and photonics outreach programs share science, spark fascination with light 2Optics and photonics outreach programs share science, spark fascination with light 3Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 2Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 3Mystic Ink 's Short Story Collection “A Short Walk to the Other Side” Honoring Ray Bradbury Praised As Award-Winning Finalist In USA Best Book Awards 4Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 2Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 3Synthetic Biology Market Expected to Reach $5,630.4 Million in 2018 - New Report by MarketsandMarkets 4City of Fayetteville Leads Nation with Innovative Ozone Technology 2City of Fayetteville Leads Nation with Innovative Ozone Technology 3City of Fayetteville Leads Nation with Innovative Ozone Technology 4
... LAIYANG, China, Sept. 2 /PRNewswire-Asia-FirstCall/ -- Jiangbo,Pharmaceuticals, Inc. (OTC ... with its principal operations in the People,s,Republic of China, ... will,present at the upcoming Rodman & Renshaw Annual Global ... New York Palace Hotel in New York City. , ...
... , , SOUTH SAN ... announced the first commercial sales of a new ... treatment of New York Heart Association Class III and IV ... same dose of Ventavis in half the volume, which is ...
... KALAMAZOO, Mich., Sept. 1 Stryker Corporation (NYSE: ... , Lonny J. Carpenter, currently Group President, ... President, Global Quality and Operations, reporting to Stephen P. MacMillan, ... Carpenter will be responsible for setting and executing company-wide quality, ...
Cached Biology Technology:Jiangbo Pharmaceuticals to Present at Rodman & Renshaw Annual Global Investment Conference 2Jiangbo Pharmaceuticals to Present at Rodman & Renshaw Annual Global Investment Conference 3Actelion Launches Increased Strength Formulation of Ventavis (Iloprost) for Pulmonary Arterial Hypertension in the United States 2Actelion Launches Increased Strength Formulation of Ventavis (Iloprost) for Pulmonary Arterial Hypertension in the United States 3Stryker Announces Organizational Changes 2
(Date:11/18/2014)... , Nov. 18, 2014  The Secure Identity ... Association today jointly announce the formation of The ... of its Identity and Biometric Entry and ... Framework received official support from BORDERPOL, the international ... improve and provide expertise regarding border security, traveler ...
(Date:11/15/2014)... 13, 2014  While we may still be a few ... in "Star Trek" to gain instant access to all that ... with smartphones and tablets for monitoring and measuring our health ... This may seem a tad Orwellian to some, but a ... of these technological opportunities into their healthcare regime. ...
(Date:11/7/2014)... associate professor, biomedical engineering, in the Grove School ... York, have identified a molecule that could lead ... aggressive forms of breast cancer. , Triple negative ... owing to aggressive proliferation and metastasis and a ... team, discovered the overexpression of intercellular adhesion molecule-1 ...
Breaking Biology News(10 mins):Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4
... Scientists are calling for more research on the possibility ... renowned for their apparent ability to prevent cancer ... individuals. Their recommendation follows a study in which two ... to aggravate kidney cancer in severely diabetic laboratory rats. ...
... the abstracts to be presented at the EORTC-NCI-AACR [1] Symposium on ... before the meeting at 00.01 hrs CET on Friday 29 October. ... are free to report on the online abstracts from the time ... bear in mind that all the abstracts had to be submitted ...
... , Blacksburg, Va. -- The USDA,s National Institute of ... the College of Agriculture and Life Sciences at Virginia ... grape and wine quality in the eastern United States. ... project director, the five-year project seeks to create, refine, ...
Cached Biology News:Abstracts for the EORTC-NCI-AACR Symposium in Berlin go up online on Friday, Oct. 29 2USDA awards Virginia Tech $3.8 million to stimulate eastern US wine industry 2
... N. Fernandez and G. Butcher (1998). • ... of much research in the immunology area. ... of MHC proteins and in their function ... now faced with the prospect of tackling ...
delta-like 1 homolog (Drosophila)...
ELISpot kit for human Granzyme B. Kits contain PVDF plates, capture & detection antibodies, streptavidin-ALP, BSA, Skimmed dry milk, BCIP/NTB substrate, and wash buffer...
SHEEP ANTI ECHIS OCCELATUS (VENOM)...
Biology Products: