Navigation Links
Researchers turn viruses into molecular Legos
Date:10/19/2011

s how such a simple building block can create such complicated structures with diverse functions."

The researchers began by studying the factors influencing the formation of hierarchical structures.

"We noticed how collagen is secreted in confined spaces, and how its assembly into tissues can be influenced by its environment," said study lead author Woo-Jae Chung, a post-doctoral researcher in Lee's lab. "Unfortunately, collagen is a difficult material to study because it is hard to tune its physical and chemical structures. We needed a convenient model system to solve this problem."

That system was a soup of saline solution containing varying concentrations of a common bacteria-attacking virus, the M13 bacteriophage. The researchers chose the M13 virus harmless to humans and a model organism in research labs because its long, "chopstick-like" shape with a helical groove on its surface closely resembles collagen fibers.

The technique the scientists developed entails dipping a flat sheet of glass into the viral bath, then slowly pulling it out at precise speeds. The sheet emerges with a fresh film of viruses attached to it. At a pulling rate ranging from 10-100 micrometers per minute, it could take 1-10 hours for an entire sheet to be processed.

By adjusting the concentration of viruses in the solution and the speed with which the glass is pulled, the researchers could control the liquid's viscosity, surface tension, and rate of evaporation during the film growth process. Those factors determined the type of pattern formed by the viruses. The researchers created three distinct film patterns using this technique.

With a relatively low viral concentration of up to 1.5 milligrams per milliliter, regularly spaced bands containing filaments oriented at 90 degree angles to each other were formed.

With a slower pulling rate came increased physical constraints to the movement and orientation of the viruses.
'/>"/>

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. UBC researchers invent tiny artificial muscles with the strength, flexibility of elephant trunk
2. Notre Dame researchers awarded millions to develop radically new computers
3. 1 room -- 63 different dust particles? Researchers aim to build dust library
4. Mirage-effect helps researchers hide objects
5. Boston College Researchers discover 2 early stages of carbon nanotube growth
6. Researchers use carbon nanotubes to make solar cells affordable, flexible
7. Roche Researchers Sequence Complete Genome of Cynomolgus Monkey and Develop Novel Gene Expression Microarray for Drug Safety Assessment
8. Slippery slope:Researchers take advice from a carnivorous plant
9. University of Western Ontario researchers investigate stress and breast cancer
10. Rice researchers power line-voltage light bulb with nanotube wire
11. Stevens researchers pioneer novel technique to make plasmonic nanogap arrays
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers turn viruses into molecular Legos
(Date:9/30/2014)... of one of nature,s most efficient light-harvesting structures, ... by Alejandro Briseno of the University of Massachusetts ... long-sought polymer architecture to boost power-conversion efficiency of ... , Briseno, with colleagues and graduate students ... and Dresden University of Technology, Germany, report in ...
(Date:9/30/2014)... Sept. 30, 2014 Report Details ... highest potential revenues Do you want to find ... you revenue predictions for those biological drugs from ... you find financial data, R&D trends, opportunities and ... sales forecasts to 2024 at overall world market, ...
(Date:9/30/2014)... , Sept. 30, 2014 Nematicide is ... nematodes. Nematodes are microscopic parasitic roundworms, found in ... inside other plants and animals. Nematicides have tended ... other properties promoting migration through the soil. A ... 1,000 plant-parasitic nematodes. With more than 10,000 species ...
(Date:9/30/2014)... Proove Biosciences , the commercial and research ... new genetic test built upon research from their published ... will provide physicians with an objective way to understand ... stratified between individuals. With this new test, physicians will ... genetic predisposition that will affect their pain tolerance. , ...
Breaking Biology Technology:Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 4Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 5Nematicides Market by Types (Fumigants, Organophosphates, Carbamate and Bio-Nematicides), Applications (Agrochemicals, Industrial, and Others), and Geography (North America, Europe, Asia-Pacific & ROW) - Global Trends & Forecasts to 2019 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3
... ( http://www.amdl.com ),AMDL, Inc. (Amex: ADL ), ... China and the US, today announced that the,Company will ... New,York City on Tuesday, October 7, 2008 at 10:30 ... Hyatt New York Hotel in the Morosco Room., ...
... Proceeds to Support R&D Efforts and Clinical ... BETHESDA, Md., Oct. 3 Micromet, Inc. ... company developing,novel, proprietary antibodies for the treatment ... that it has closed its previously,announced $40 ...
... of Aberdeen and Rothamsted Research for releasing natural insect repellents that ... technology is set to revolutionise how people protect buildings from unwanted ... ... (PRWEB) October 3, 2008 -- Atrium Innovation Ltd has developed a ...
Cached Biology Technology:AMDL, Inc. to Present at Maxim Group Growth Conference October 7, 2008 2AMDL, Inc. to Present at Maxim Group Growth Conference October 7, 2008 3Micromet Closes $40 Million Private Equity Placement 2Micromet Closes $40 Million Private Equity Placement 3Micromet Closes $40 Million Private Equity Placement 4New Innovation Set to Revolutionise Spray Technology - Used to Protect Against the Scottish Biting Midge & Help Fight MRSA in the NHS 2New Innovation Set to Revolutionise Spray Technology - Used to Protect Against the Scottish Biting Midge & Help Fight MRSA in the NHS 3New Innovation Set to Revolutionise Spray Technology - Used to Protect Against the Scottish Biting Midge & Help Fight MRSA in the NHS 4
(Date:9/30/2014)... assessment conducted by the Ocean Health Index rates ... in overall health. In addition, for the first ... 15 ocean regions beyond national jurisdiction (high-seas areas) ... climate, safeguarding biodiversity and providing sustainable food sources. ... index, a partnership led by scientists from UC ...
(Date:9/30/2014)... professor and Howard Hughes Medical Institute investigator, and ... recipients in the 2014 round of grants from ... BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative ... September 30, provides more than $3 million in ... , The BRAIN Initiative, launched last year, is ...
(Date:9/30/2014)... live in almost any aquatic environment on Earth, but ... species are pushed to the limit. The amount of ... critical for how different species cope in the future, ... of Gothenburg, published in the scientific journal Proceedings ... continues apace thanks to increasing levels of greenhouse gases ...
Breaking Biology News(10 mins):Rating the planet's oceans 2Rating the planet's oceans 3Salk scientists receive $3 million for BRAIN Initiative grant 2Shape up quickly -- applies to fish, too! 2
... When ordering seafood, the options are many and so are ... Is your fish healthy? Is it safe? Is it endangered? While ... there,s even an iPhone app a group of researchers ... fish is sustainable, then it is likely to be healthy to ...
... States, one in 10 children suffers from asthma but ... not well known. Cincinnati-based researchers now report new evidence ... may have a direct link to asthma development during ... unguis and Penicillium variabileare typically found growing in water-damaged ...
... heavy rains and droughts that climate change will bring, says ... at a contentious U.S. Senate hearing on climate change, Stanford,s ... yet hopeful analogy. Just as speeding increases the chance ... of heat waves, droughts and heavy precipitation, said Field, a ...
Cached Biology News:Study finds healthy seafood comes from sustainable fish 2Infants exposed to specific molds have higher asthma risk 2Stanford expert brings climate change science to heated Capitol Hill 2
... Mouse polyclonal antibody raised against ... Immunogen: PPP4C ... a.a) partial recombinant protein with ... Accession Number: NM_002720 ...
... Eppendorf Thermomixer R offers maximum application ... shaking, heating, and cooling. Its active ... application and temperature control ranges. Five ... 24 micro test tubes, are available ...
Mouse monoclonal antibody raised against a partial recombinant PDE2A. NCBI Entrez Gene ID = PDE2A...
... II can be used to test the ... and sera that are commonly used as ... contains spots for 19 different protein preparations ... antibody crossreactivity and species specificity, QC of ...
Biology Products: