Navigation Links
Researchers identify signals that direct the immune system to reject a transplanted organ
Date:5/17/2013

Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ. In this issue of the Journal of Clinical Investigation, Fadi Lakkis and colleagues at the University of Pittsburgh used mice to demonstrate that chemokine stimulation of T cells is not required for migration. Instead, these cells must come into contact with immune-stimulating proteins (antigens) that are specifically expressed by the transplanted organ. In an accompanying commentary, Terry Strom discusses how these findings could have important implications for the design of novel anti-rejection therapeutics.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Top Genetic and Cellular Researchers Honored at ASGCT 16th Annual Meeting
2. Pioneering Researchers Recognized for Scientific Achievements in Gene and Cell Therapy
3. SPIE Smart Structures/NDE Researchers Look to Nature for Inspiration
4. South Dakota School of Mines & Technology Researchers Document Splitting Water Molecules in Multiple Thermochemical Cycles with Goal to Sustain Hydrogen Energy
5. Israel’s Top BioEnergy Researchers Are Arriving Today at Oak Ridge National Laboratory For Deliberations to Establish U.S.-Israel Collaboration
6. Researchers untangle molecular pathology of giant axonal neuropathy
7. Top BioEnergy Researchers and Innovators Arriving Next Week to Foster U.S.-Israel Collaboration
8. Researchers identify transcription factors that regulate retinal vascularization
9. Bean leaves can trap bedbugs, researchers find
10. Elsevier and the Belarus Ministry of Education Honor Researchers with Scopus Awards
11. Beekeepers, Researchers and Bayer CropScience Associate Overwintering Bee Losses with Varroa Mite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... , July 30, 2015   GenoSpace , ... the interpretation and analysis of genomic and other ... has joined the company as Vice President ... http://photos.prnewswire.com/prnh/20150730/250931 "GenoSpace partners ... integrate, interpret, analyze and explore complex sets of ...
(Date:7/30/2015)... ... ... The 2015 Market Research Report on the Global Propanol Industry is ... with a focus on the Chinese situation. Major companies included in the propanol market ... Royal Dutch Shell, LG Chem and Zhejiang Xinhua Chemical. , The report provides a ...
(Date:7/30/2015)... San Diego , CA (PRWEB) , ... July ... ... Biopharma, announced the successful completion of a field clinical study of its canine ... being developed together with Aratana Therapeutics (Kansas City, KS) and will be marketed ...
(Date:7/30/2015)... 2015   Senomyx , Inc. (NASDAQ: SNMX ... to discover, develop, and commercialize novel flavor ingredients for ... financial results for the second quarter 2015. ... remain on track to achieve our commercial and financial ... of the Company. "Since our last quarterly earnings report, ...
Breaking Biology Technology:GenoSpace Introduces Matthew Fischer as Vice President of Sales and Marketing 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 3VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 4SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 5SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 6SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 7SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 8SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 9
... will bike down the California coast to ... and help those affected by arthritis, SAN FRANCISCO, Sept. ... annual Amgen California Coast Classic,Bike Tour on Saturday, September 29 ... over eight days, aim to raise more,than $1.3 million this ...
... N.C., Sept. 21 Campbell Alliance, the ... and biotech,industries, today announced that Ben Bonifant, ... practice, will moderate a panel discussion,at the ... Information. The conference will be held September ...
... Roche has,advised Maxygen, Inc. (Nasdaq: MAXY ) ... development of MAXY-alpha, also known as R7025.,MAXY-alpha is a ... B virus infections and is licensed to Roche. ... an,unexpected reduction of the pharmacodynamic and pharmacokinetic effects of,MAXY-alpha ...
Cached Biology Technology:More Than 230 Cyclists to Ride in Amgen California Coast Classic Bike Tour to Raise $1.3 Million for Arthritis Foundation 2Campbell Alliance to Moderate Senior-Level Panel Discussion at Windhover Pharmaceutical Strategic Alliances Conference 2Campbell Alliance to Moderate Senior-Level Panel Discussion at Windhover Pharmaceutical Strategic Alliances Conference 3Maxygen Announces Hold on MAXY-alpha Development Program 2Maxygen Announces Hold on MAXY-alpha Development Program 3
(Date:7/21/2015)... NEW YORK , July 21, 2015 /PRNewswire/ ... critical systems, as seen in the recent U.S. ... enterprises a solution to the infosec conundrum, but ... data is stored. To address this dilemma, Biometrics-as-a-Service ... of its Biometric Tokenization SDK for third party ...
(Date:7/9/2015)...  Synaptics Inc. (NASDAQ: SYNA ), a leading developer ... report financial results for the fourth quarter and fiscal ... close of market. The company will host a corresponding ... PT (5:00 p.m. ET), during which management may discuss ... live call, analysts and investors should dial 888-455-2260 (conference ...
(Date:7/8/2015)... July 8, 2015 Summary Pancreatic cancer ... fourth most fatal, with a mortality rate of 10.9 ... of pancreatic cancer patients has highlighted a significant need ... not being met by the current market. A ... products with varying molecule types and mechanisms of action, ...
Breaking Biology News(10 mins):HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3
... University of California, Riverside biologists working on guppies ... of long-term studies report that rapid growth responses ... restriction early in life have repercussions in adulthood. ... guppies that grew rapidly as juveniles produced fewer offspring ...
... without a class system of managers and workers? That,s ... solved: How did a prehistoric, egalitarian people called the ... a "manager" hierarchy? Archaeologists from Southern Methodist University ... the Gila River Indian Community in Arizona have launched ...
... for a severe inflammatory disease that has spread along ... to the edge of Europe. University of Manchester ... have revealed some of the genetic mutations that lead ... Nature Genetics . Behet,s is a vascular ...
Cached Biology News:Rapid growth in adolescence leads to fewer offspring, UC Riverside biologists find 2Rapid growth in adolescence leads to fewer offspring, UC Riverside biologists find 3New research will unravel Arizona's prehistoric puzzle of the Hohokam ceramic industry 2New research will unravel Arizona's prehistoric puzzle of the Hohokam ceramic industry 3New research will unravel Arizona's prehistoric puzzle of the Hohokam ceramic industry 4Disease genes that followed the Silk Road identified 2
Rabbit polyclonal to Testosterone 19 ( Abpromise for all tested applications). Antigen: Testosterone 19 CME HSA (Human)...
Kinase Buffer can be used to assay protein kinase activity...
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
alpha/beta-Tubulin Antibody Ship: Hot Store: -20 C...
Biology Products: