Navigation Links
Researchers identify signals that direct the immune system to reject a transplanted organ
Date:5/17/2013

Organ transplant rejection occurs when the transplant recipient's immune system identifies the transplanted organ as foreign tissue and attacks it. It was previously thought that T cells, the immune cells that mediate rejection, must first be activated by molecules known as chemokines in order to migrate to the transplanted organ. In this issue of the Journal of Clinical Investigation, Fadi Lakkis and colleagues at the University of Pittsburgh used mice to demonstrate that chemokine stimulation of T cells is not required for migration. Instead, these cells must come into contact with immune-stimulating proteins (antigens) that are specifically expressed by the transplanted organ. In an accompanying commentary, Terry Strom discusses how these findings could have important implications for the design of novel anti-rejection therapeutics.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Top Genetic and Cellular Researchers Honored at ASGCT 16th Annual Meeting
2. Pioneering Researchers Recognized for Scientific Achievements in Gene and Cell Therapy
3. SPIE Smart Structures/NDE Researchers Look to Nature for Inspiration
4. South Dakota School of Mines & Technology Researchers Document Splitting Water Molecules in Multiple Thermochemical Cycles with Goal to Sustain Hydrogen Energy
5. Israel’s Top BioEnergy Researchers Are Arriving Today at Oak Ridge National Laboratory For Deliberations to Establish U.S.-Israel Collaboration
6. Researchers untangle molecular pathology of giant axonal neuropathy
7. Top BioEnergy Researchers and Innovators Arriving Next Week to Foster U.S.-Israel Collaboration
8. Researchers identify transcription factors that regulate retinal vascularization
9. Bean leaves can trap bedbugs, researchers find
10. Elsevier and the Belarus Ministry of Education Honor Researchers with Scopus Awards
11. Beekeepers, Researchers and Bayer CropScience Associate Overwintering Bee Losses with Varroa Mite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2017)... ... April 21, 2017 , ... The AMA is happy to announce that $48,000 ... the nation. The scholarships are created through funds donated by model aviation organizations and ... set by the AMA Scholarship Committee, which is made up of model aviation pilots ...
(Date:4/21/2017)... ... 21, 2017 , ... Frederick Innovative Technology Center, Inc. (FITCI), ... businesses, recently earned a $77,518 grant from the Rural Maryland Council (RMC) to ... is Frederick’s first incubator. A non-profit corporation, FITCI is a public-private partnership of ...
(Date:4/20/2017)... ... April 20, 2017 , ... ... announced their strategic partnership to offer a full spectrum of digital security goods ... suite of biometric products and the ground-breaking proactive cybersecurity services and products through ...
(Date:4/20/2017)... ... 20, 2017 , ... USDM Life Sciences , the leading risk management, ... is pleased to announce Holger Braemer as Vice President of its Europe ... in Germany. , Braemer is an integral part of USDM’s expansion of services ...
Breaking Biology Technology:
(Date:4/5/2017)... 5, 2017 Today HYPR Corp. , ... server component of the HYPR platform is officially ... end-to-end security architecture that empowers biometric authentication across Fortune ... already secured over 15 million users across the financial ... connected home product suites and physical access represent a ...
(Date:4/3/2017)... , April 3, 2017  Data ... precision engineering platform, detected a statistically significant ... product prior to treatment and objective response ... the potential to predict whether cancer patients ... to treatment, as well as to improve ...
(Date:3/30/2017)... 2017 Trends, opportunities and forecast in this ... technology (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, ... end use industry (government and law enforcement, commercial and ... and others), and by region ( North America ... Asia Pacific , and the Rest of the ...
Breaking Biology News(10 mins):