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Researchers find 'Goldilocks' of DNA self-assembly
Date:10/28/2010

old over on themselves," Yingling explains. That leaves them exposed, and available to bond with the materials in another layer the perfect situation for DNA self-assembly.

One potential application for such self-assembling materials is the development of drug-delivery vehicles. For example, researchers at the University of Melbourne have created self-assembling DNA capsules that are fully biocompatible, biodegradable and capable of releasing the drug when they come in contact with a specific physical stimulus making them ideal for drug delivery.

DNA self-assembly technology is also expected to facilitate the creation of molecular sensors that use DNA to detect, and signal the presence of, clinically important biological molecules which could have significant diagnostic applications in the medical field.

"We're now planning to explore additional factors that play a role in DNA self-assembly," Yingling says, "including temperature, genetic sequence and the environment in which the assembly takes place."


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Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University
Source:Eurekalert  

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