Navigation Links
Researchers find 'Goldilocks' of DNA self-assembly
Date:10/28/2010

Researchers from North Carolina State University have found a way to optimize the development of DNA self-assembling materials, which hold promise for technologies ranging from drug delivery to molecular sensors. The key to the advance is the discovery of the "Goldilocks" length for DNA strands used in self-assembly not too long, not too short, but just right.

DNA strands contain genetic coding that will form bonds with another strand that contains a unique sequence of complementary genes. By coating a material with a specific DNA layer, that material will then seek out and bond with its complementary counterpart. This concept, known as DNA-assisted self-assembly, creates significant opportunities in the biomedical and materials science fields, because it may allow the creation of self-assembling materials with a variety of applications.

But, while DNA self-assembly technology is not a new concept, it has historically faced some significant stumbling blocks. One of these obstacles has been that DNA segments that are too short often failed to self-assemble, while segments that are too long often led to the creation of deformed materials. This hurdle can lead to basic manufacturing problems, as well as significant changes in the properties of the material itself.

A team of researchers from NC State and the University of Melbourne have proposed a solution to this problem, using computer simulations of DNA strands to identify the optimal length of a DNA strand for self-assembly and explaining the scientific principles behind it.

"Strands that are too short or long form self-protected motifs," says Dr. Yara Yingling, an assistant professor of materials science and engineering at NC State and co-author of a paper describing the research. That means that the strands bond to each other, rather than to "partner" materials.

"The optimal lengths are not long enough to intertwine with each other, and are not short enough to f
'/>"/>

Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Plague researchers race to beat bioterrorists
2. Microsoft Research Makes Microsoft Biology Foundation and MODISAzure-Based Environmental Service Available to Scientists and Researchers
3. Plague researchers race to beat bioterrorists
4. Researchers sequence genome of mosquito that spreads West Nile virus
5. Elsevier Survey Reveals Researchers Ready to Push Scientific Search and Discovery to the Next Level
6. Researchers discover less expensive low-temperature catalyst for hydrogen purification
7. Researchers expand yeasts sugary diet to include plant fiber
8. NIST researchers hear puzzling new physics from graphene quartets quantum harmonies
9. Virginia Tech researchers contribute to turkey genome sequencing
10. Researchers create new class of piezoelectric logic devices using zinc oxide nanowires
11. Researchers stretch a lackluster material into a possible electronics revolution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Researchers find 'Goldilocks' of DNA self-assembly
(Date:8/28/2015)... Brooklyn, NY (PRWEB) , ... August 28, 2015 , ... Since the initial launch of ... with their quirky humor and excellent customer service. Images such as the Fonz in ... website to add some flavor to the humdrum spectroscopy field. , FireflySci is ...
(Date:8/27/2015)... , Aug. 27, 2015  Neogen Corporation (NASDAQ: ... the stock of United Kingdom -based ... microbiological culture media and diagnostic systems. ... into a leading provider of microbial testing and diagnostic ... testing markets. The company currently sells into more than ...
(Date:8/27/2015)... Aug. 27, 2015  Asterias Biotherapeutics, Inc. (NYSE MKT: ... of regenerative medicine, today announced that executives from the ... month of September.  , Pedro ... & Renshaw,s 17th Annual Global Investment Conference on Wednesday, ... St. Regis Hotel in New York City ...
(Date:8/27/2015)... GlassesOff (OTCBB: GLSO), a visual neuroscience technology company ... system, announced today a partnership with eight-time All-Star, ... to develop a new mobile app designed for professional and ... performance. Vision is the inception of every move ... or blocking a pass. The critical impact vision speed has ...
Breaking Biology Technology:Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2Neogen acquires U.K.-based Lab M Holdings 2Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 2Eight-Time All-Star Chris Paul and GlassesOff Partner to Develop Innovative Mobile App Designed to Improve On-Court Performance 3
... SOUTH SAN FRANCISCO, Calif., Nov. 24 Poniard,Pharmaceuticals, ... company focused on,oncology, today announced an agreement with ... of injectable picoplatin drug product.,Poniard is developing picoplatin, ... product for the treatment of solid tumors. ...
... Probiotics Council,(GPC), a committee formed by Groupe DANONE ... two grants for the second annual Young,Investigator Grant ... will provide $50,000 over one year. This year, ... and gastrointestinal microbiota in health,and disease. The grants ...
... of quantum computing is that it will dramatically outshine ... databases, factoring large numbers, creating uncrackable codes and simulating ... in that direction, if you,ll pardon the pun, has ... in a paper published in the journal Nature ...
Cached Biology Technology:Poniard Pharmaceuticals Announces Commercial Supply Agreement for Picoplatin 2Poniard Pharmaceuticals Announces Commercial Supply Agreement for Picoplatin 3New Young Investigator Grants for Probiotics Research Announced 2New Young Investigator Grants for Probiotics Research Announced 3New Young Investigator Grants for Probiotics Research Announced 4Stanford: Quantum computing spins closer 2
(Date:8/11/2015)... 2015 Today, ZUK announced its Android smartphone ... as expected revenues in 2015 that relate to sales of FPC1155 ... of approximately 2,200 MSEK for 2015. Jörgen Lantto, CEO ... prominent smartphone manufacturer in China ... FPC1 155 for Z1 , ...
(Date:8/6/2015)... Aug. 6, 2015  Today, U.S. Congressman ... Crossmatch ™ to learn firsthand how Silicon Valley ... Crossmatch is a world leader in multi-factor identity ... are helping federal agencies and commercial organizations achieve ... "The vast majority of network breaches ...
(Date:8/5/2015)... August 5, 2015 According to ... Management Market by Software, Services, Vertical (BFSI, Airport, IT & ... - Global Forecast to 2020", published by MarketsandMarkets, defines ... globally into various segments. The global PIAM Market is ... $546.2 Million by 2019, at a CAGR of 14.9 ...
Breaking Biology News(10 mins):FPC's Touch Fingerprint Sensor FPC1155 in ZUK's Smartphone Z1 2Rep. Honda to Visit Crossmatch in Redwood City 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4
... , Dec. 6, 2013 /PRNewswire-iReach/ -- Afterburn Fuel ... information about the pre workout supplement called Afterburn ... (Photo: http://photos.prnewswire.com/prnh/20131206/MN28972 ) ... product, what it contains, and where they can purchase ...
... preventing childhood asthma isn,t one of them, shows newly published ... , Meghan Azad, a Banting post-doctoral fellow in the Faculty ... the principal investigator on the findings that appeared in the ... data from 20 clinical trials in Europe, Australia, New Zealand ...
... but often energy is being wasted maintaining empty rooms ... published in the International Journal of Communication Networks ... smart phones connected to the office network could be ... conditioning for unused spaces. Bruce Nordman of the ...
Cached Biology News:Afterburn Fuel Review Announces the Launch of its New and Informative Website 2Taking probiotics in pregnancy or giving them to infants doesn't prevent asthma 2The heat is on...or off 2
PE Rat anti-Hu CD267 Storage Temperature: Refrigerate(2 to 8C)...
Leucine-rich repeat-containing G-protein coupled receptor 4...
WD-repeat protein 4...
Rabbit polyclonal to MDM2 (phospho S185) ( Abpromise for all tested applications). entrezGeneID: 4193 SwissProtID: Q00987...
Biology Products: