Navigation Links
Researchers Pinpoint Best Treatment to Reduce Deadly USA300, MRSA Staph Infections
Date:1/23/2008

CORVALLIS, Ore., Jan. 23 /PRNewswire/ -- According to a recent College of Pharmacy study at Oregon State University, one type of over-the-counter product for minor wound care is substantially more effective than others in killing MRSA, including the virulent strain USA300. Scientists conducting the study compared three common over-the-counter wound care treatments for effectiveness against four strains of community acquired MRSA. Breaks in the skin, such as cuts and scrapes, are the most common entry point for the highly aggressive staph bacteria.

The new laboratory study showed that standard OTC antibacterial products are helpful for preventing common infections but only one product, Staphaseptic, made by Tec Laboratories, was effective in killing MRSA and the USA300 strain. The ointment-like gel, made with Benzethonium chloride, tea tree oil and white thyme oil, killed MRSA quicker and more effectively than the other compounds tested and had a sustained killing effect for 24 hours.

"We wanted to try these common OTC wound-treating products to see if they would kill a wide range of MRSA strains since MRSA has mutated significantly into more than one strain," said Oregon State's Dr. J. Mark Christensen, one of the authors of the study.

According to information from OSU, scientists there found that each of the products tested had some effectiveness, but only the Staphaseptic product had a genuine "bactericidal" effect -- meaning it reduced the number of bacteria by a factor of 1,000 -- against all four of the tested MRSA strains. The four strains tested were USA300-1, USA300-2, USA300-3, and USA400.

Also included in the testing were products made with neomycin and polymyxin; and another made with polymyxin and gramicidin. All three of the compounds used in the tests are widely available over the counter at national drug store chains. Staphaseptic is relatively new, while the other two are commonly found, with slight variations, in "maximum strength" or "triple antibiotic" compounds routinely sold in drug stores.

The USA300 strain of MRSA was put in the spotlight recently in a study published online by The Annals of Internal Medicine. Results showed that at one Boston area health clinic monitored in the study, 97% of patients infected with MRSA had the USA300 strain. The AIM study was led by Dr. Binh Diep who stressed the urgent need for prevention of these potentially deadly infections.

"Once this reaches the general population, it will be truly unstoppable," said Diep. "That's why we're trying to spread the message of prevention."

Researchers conducting the Oregon State University study also focused on prevention by testing products that are commonly used to prevent various infections in cuts and scrapes, rather than testing more expensive prescription antibiotics that attempt to kill the superbug after a severe infection takes hold.

The study was recently presented at a meeting of the American Society of Health-System Pharmacists by Dr. David Bearden, a specialist in infectious diseases and an author of the study. Dr. George P. Allen joined Bearden and Christensen as the third author.

"Staphaseptic remained bactericidal for 24 hours, which surprised me," said Christensen. "Usually you see an initial kill, which is followed by the bacteria growing again. But Staphaseptic blunted this regrowth and suppressed the bacteria, showing killing for up to 24 hours."

According to Bearden, USA300 is being passionately studied for a reason. "USA300 has become the predominant strain in severe community-acquired skin infections. The strain is more virulent and infects individuals who are otherwise healthy, something that earlier hospital strains of MRSA did not."

A copy of the original OSU Time Kill study can be viewed by following this link http://www.teclabsinc.com/press_docs/MRSA_Study.pdf
Available Topic Expert(s): For information on the listed expert(s), click appropriate link. Mark Christensen http://profnet.prnewswire.com/Subscriber/ExpertProfile.aspx?ei=56557 Dave Bearden http://profnet.prnewswire.com/Subscriber/ExpertProfile.aspx?ei=67976


'/>"/>
SOURCE Tec Laboratories, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. Researchers develop darkest manmade material
2. Boost for Malaria Vaccine Development by Combining Strengths of Dutch and American Researchers
3. Researchers use magnetism to target cells to animal arteries
4. Ames Laboratory researchers solve fuel-cell membrane structure conundrum
5. Researchers outline structure of largest nonvirus particle ever crystallized
6. UD researchers race ahead with latest spintronics achievement
7. ASU researchers improve memory devices using nanotech
8. Researchers underscore limitations of genetic ancestry tests
9. Researchers measure carbon nanotube interaction
10. Stevens researchers provide new information about mass spectrometry
11. CU researchers shed light on light-emitting nanodevice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... and HOUSTON , ... ("NX Prenatal") today announced the formation of its ... leading clinicians and industry veterans who enhance the ... as it accelerates development of its novel prenatal ... provide medical, clinical and strategic guidance for the ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... software to leading biopharmaceutical and medical device manufacturers and regulators, is proud to ... CFR Part 11-compliant email client designed to provide product vigilance departments with the ...
(Date:1/19/2017)... ... 2017 , ... The American Medical Informatics Association (AMIA) today ... Policy. Specifically, the nation’s leading informatics experts, said data sharing plans should be ... recommended that NIH earmark funding for researchers to produce and execute data sharing ...
(Date:1/19/2017)... 18, 2017 The global biotechnology services ... billion by 2025, according to a new report ... been adaptive of the function of outsourcing certain ... Among the services outsourced, clinical trial management and ... & Johnson was the first pharmaceutical company to ...
Breaking Biology Technology:
(Date:12/22/2016)... 20, 2016  As part of its longstanding mission to ... genetics company, recently released its latest children,s book, titled ... focuses on the topics of inheritance and variation of traits ... taught in elementary school classrooms in the US. ... illustrator Ariana Killoran , whose previous book with 23andMe, ...
(Date:12/16/2016)... --  IdentyTechSolutions America LLC , a leading provider ... a cutting-edge manufacturer of software and hardware security ... integrated solutions that comprise IDT biometric readers and ... IdentyTech,s customers with combined physical identification and anti-tailgating ... theft. "We are proud to use ...
(Date:12/15/2016)... ... and Markets has announced the addition of the "Global Military Biometrics ... forecasts the global military biometrics market to grow at a CAGR of ... prepared based on an in-depth market analysis with inputs from industry experts. ... coming years. The report also includes a discussion of the key vendors ...
Breaking Biology News(10 mins):