Navigation Links
Researchers Find Potential Link Between Drinking Alcohol And Breast Cancer
Date:4/23/2012

SAN DIEGO, April 23, 2012 /PRNewswire-USNewswire/ -- A research team this week will present findings that they say may finally explain the link between alcohol consumption and breast cancer.

"Cells have different mechanisms to remove toxic substances, such as ethanol, the chemical name for alcohol, that represent a potential risk to them," explains Maria de Lourdes Rodriguez-Fragoso, professor of pharmacology and toxicology at the Universidad Autonoma del Estado de Morelos in Mexico. "Unfortunately, sometimes these mechanisms produce other toxic substances, including some that are associated with the development of different types of cancer."

At 12:25 p.m. Monday, April 23, Rodriguez-Fragoso will present her group's work at the annual meeting of the American Society for Biochemistry and Molecular Biology, held in conjunction with the Experimental Biology 2012 conference in San Diego.

Alcohol consumption has long been established as a risk factor for breast cancer. But finding the direct link that makes it so has, so far, proved elusive. Now, Rodriguez-Fragoso and her collaborators think that they have found the answer, a protein called CYP2E1.

"We knew that CYP2E1 could break down ethanol and that doing so created unstable, highly reactive chemicals known as free radicals," she says. Working with researcher Scott Burchiel and his group at the University of New Mexico, Rodriguez-Fragoso's team had previously found that free radicals were associated with activation of cellular mechanisms that lead to tumor development. "The question then was, does having more CYP2E1 make you more susceptible to ethanol-induced toxicity, thereby increasing your risk of developing cancer?"

CYP2E1 is found in breast cells known as mammary epithelial cells, which are also where most breast cancers originate, suggesting to the researchers that CYP2E1 may be involved in breast cancer development. To test this hypothesis, the researchers administ
'/>"/>

SOURCE American Society for Biochemistry and Molecular Biology
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Quality Standards Established for Competition to Identify Best Researchers in the US
2. Researchers reveal why some pain drugs become less effective over time
3. Researchers Identify New Regulator in Allergic Diseases
4. CNIO researchers take part in the most comprehensive personalized medicine study performed to date
5. Researchers develop graphene supercapacitor holding promise for portable electronics
6. Researchers capture first-ever images of atoms moving in a molecule
7. Penn researchers build first physical metatronic circuit
8. Pitt researchers coax gold into nanowires
9. York researchers create tornados inside electron microscopes
10. Self-assembling nanorods: Berkeley Lab researchers obtain 1-, 2- and 3-D nanorod arrays and networks
11. Navy researchers investigate small-scale autonomous planetary explorers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2015)... Greifensee, Switzerland (PRWEB) , ... August 27, 2015 ... ... input on customers’ weighing needs and expertly narrows down the product choices to ... additional selection criteria pares down the list to models that fit best with ...
(Date:8/26/2015)... KS (PRWEB) , ... August 26, 2015 , ... ... Biologic Solutions, announces today that a second US laboratory is to open in ... accordance with the continued partnership and long-term growth of research and development through ...
(Date:8/26/2015)... ... 26, 2015 , ... Lee Biosolutions, a global biotech healthcare ... of highly valued cardiac markers used in early detection of heart disease due ... has led to the development and commercialization of important cardiac biomarkers used in ...
(Date:8/26/2015)... 2015 Intrexon Corporation (NYSE: XON ), ... of its previously announced public offering of common stock, ... their option to purchase an additional 731,707 shares of ... per share.  The exercise of the underwriters, option brought ... by Intrexon to 5,609,756 shares and increased the total ...
Breaking Biology Technology:METTLER TOLEDO Updates Online Scale Selection Tool 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 3Lee Biosolutions Announces Increased Investment in the Development and Manufacturing of Biomarkers Used in Early Detection Of Heart Disease 2Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 2Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 3Intrexon Announces Closing of $230 Million Public Offering of Common Stock including Full Exercise of Underwriters' Option to Purchase Additional Shares 4
... technique for inducing nanorods - rod-shaped semiconductor nanocrystals ... three-dimensional macroscopic structures has been developed by a ... Energy (DOE),s Lawrence Berkeley National Laboratory (Berkeley Lab). ... nanorods in solar cells, magnetic storage devices and ...
... Cepheid (NASDAQ: CPHD ) today announced that ... and invited investors to participate via webcast. Leerink ... 2012 at 11.30 a.m. Eastern Time Raymond James ... p.m. Eastern Time Additionally, Cepheid announced that ...
... BLUE BELL, Pa., Feb. 1, 2012  Evolution Marketing ... consulting company, announced that it has proactively restructured ... evolving global pharmaceutical marketplace in coming years. As ... instituted a new strategy called "Intelligent Efficiency." This ...
Cached Biology Technology:Self-assembling nanorods: Berkeley Lab researchers obtain 1-, 2- and 3-D nanorod arrays and networks 2Self-assembling nanorods: Berkeley Lab researchers obtain 1-, 2- and 3-D nanorod arrays and networks 3Self-assembling nanorods: Berkeley Lab researchers obtain 1-, 2- and 3-D nanorod arrays and networks 4Cepheid to Webcast Upcoming Financial Presentations 2Leading Pharmaceutical Marketing Research and Consulting Company Introduces 'Intelligent Efficiency' Program 2
(Date:8/12/2015)... --  MedNet Solutions , an innovative SaaS-based eClinical technology ... is proud to announce that iMedNet ... platform, has led the way to significant and unprecedented ...   Q2 2015 and Q1 2015 were, respectively, the ... sold in the company,s 15 year history.  In addition, ...
(Date:8/11/2015)... Today, ZUK announced its Android smartphone Z1, ... expected revenues in 2015 that relate to sales of FPC1155 for ... approximately 2,200 MSEK for 2015. Jörgen Lantto, CEO of ... smartphone manufacturer in China and ... 155 for Z1 , ...
(Date:8/6/2015)... TELTOW, Germany , August 6, 2015 ... SensoMotoric Instruments (SMI) shows the world,s first ... based on Epson,s Moverio BT-200 see-through head mounted ... this new solution, unprecedented quality and efficiency is brought ... context-sensitive displays. For the first time, professionals and researchers ...
Breaking Biology News(10 mins):MedNet Solutions Experiences Explosive Corporate Growth 2FPC's Touch Fingerprint Sensor FPC1155 in ZUK's Smartphone Z1 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 3
... the hare, the competition between native and invasive plants growing ... about how the plants cross the finish line in autumn., ... that the leaves of invasive plants continue to function in ... for the winter. The findings are counter to conventional wisdom, ...
... A Texas region containing four of the world,s largest ... nine years that researchers have connected to local meteorological effects ... west-central Texas wind farms warmed at a rate of .72 ... nearby regions without wind farms, an effect most likely caused ...
... a living cell works means knowing how the chemistry ... cell change. Protein phosphorylation, for example, controls everything from ... even programmed cell death (apoptosis), in cells from bacteria ... been intensively studied, not least in hopes of treating ...
Cached Biology News:Syracuse University study finds autumn advantage for invasive plants in eastern United States 2Syracuse University study finds autumn advantage for invasive plants in eastern United States 3NASA satellite measurements imply Texas wind farm impact on surface temperature 2Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 2Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 3Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 4Molecular spectroscopy tracks living mammalian cells in real time as they differentiate 5
...
... 96 Well BAC Prep; Ideal ... from 1.5ml 2xYT cultures; Provides ... fluorescent sequencing for small to ... strategy which minimizes shearing and ...
... Mouse monoclonal [SPM278] to 67kD Laminin Receptor, ... carcinoma N592 live cells (Human). Reactivity ... yet tested in other species. Background ... glycoproteins of basement membrane, displays multiple biological ...
Mouse Anti-Lamin B...
Biology Products: