Navigation Links
Research Using Thermo Fisher Scientific RNA-Interference Technology Unveils Potential New Targets for HIV Drugs
Date:1/31/2008

irector of the HMS Division of AIDS. The team also included Dr. Abraham L. Brass, postdoctoral researcher, working with Derek Dykxhoorn and Nan Yan, molecular virologists in Dr. Lieberman's group. Brass used the Dharmacon siGENOME siRNA Library for discovering weaknesses in pathogens such as HIV.

"HIV only expresses a few proteins, so it depends greatly on our cellular machinery during its lifecycle," said Brass. "Every time the virus relies on one of our proteins, it gives us the potential to disrupt that interaction and hurt HIV, which is very exciting. We also now have the ability to combine technology like siRNA screening with advanced robotics, giving us an incredibly powerful tool to go after devastating diseases such as HIV and cancer."

Dr. Caroline Shamu, director of the ICCB-Longwood Screening Facility, added, "Whole-genome siRNA (short-interfering RNA) screening is playing an increasingly important role in advancing genomic and proteomic research. Because it allows us to investigate the entire human genome, screening thousands of samples simultaneously, it dramatically accelerates the pace of biomedical discovery." Shamu's facility hosts the Dharmacon siGENOME siRNA Library and oversees screening conducted by researchers from Harvard Medical School and its affiliates.

The siGENOME siRNA Library is a collection of more than 21,000 siRNAs targeting every gene in the human genome. Each siRNA silences or disrupts the gene's ability to produce a specific protein. The siGENOME siRNA Library is currently used by many of the world's leading research institutions to accelerate the identification of genes important to human health.

Harvard Medical School is a member of the RNAi Global Initiative, founded by the Dharmacon products team and several leading research institutions around the world. In addition to Thermo Fisher Scientific, there are now 26 member institutions, all using the siGENOME siRNA Library and collaborating on research i
'/>"/>

SOURCE Thermo Fisher Scientific Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Cryo-Cell Announces Research Collaboration Agreement with Saneron CCEL Therapeutics, Inc.
2. BioMarin Appoints Dr. Gordon Vehar, Vice President of Research
3. Vasogens Research Published in European Journal of Neuroscience
4. Researchers Pinpoint Best Treatment to Reduce Deadly USA300, MRSA Staph Infections
5. Researchers develop darkest manmade material
6. Clinimetrics Celebrates 20th Anniversary in Contract Research Business
7. Quintiles to Open Clinical Research Office in Wilmington, NC
8. Irving Dark Named Vice President of Cytel Clinical Research Services
9. Boost for Malaria Vaccine Development by Combining Strengths of Dutch and American Researchers
10. VIA Pharmaceuticals Names Rebecca Taub Senior Vice President of Research and Development
11. Collaborative Biosecurity Research Initiative Launched to Target Animal and Public Health Threats Nationally
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Massachusetts e SHENZHEN , ... Co., LTD, (BGI Tech), una filiale di BGI, la ... lancio mondiale di un nuovo servizio di sequenziamento dell,intero ... di Complete Genomics. Complete Genomics, molto ... tecnologie di sequenziamento proprietarie con il 99.999% di precisione ...
(Date:7/22/2014)... SHENZHEN, China , July 22, ... (BGI Tech), a subsidiary of BGI, the world,s ... of a new human whole exome sequencing service ... offered service includes in-depth bioinformatics analysis and SNP ... December 31, 2014. Complete Genomics, ...
(Date:7/22/2014)... 2014 In chemical and petrochemical ... common sight. The rapid rise of TDL analyzers ... established as a core gas measurement technology, and ... them the gas analyzer technology of choice for ... in some processes have limited their application range. ...
(Date:7/22/2014)... 22, 2014  The Broad Institute today announced ... Ted Stanley aimed at galvanizing scientific ... based on molecular understanding to hundreds of millions ... The Stanley commitment – the largest ever in ... research in general – will support research by ...
Breaking Biology Technology:BGI Tech lancia un servizio di sequenziamento dell'intero esoma umano sulla piattaforma avanzata di Complete Genomics 2BGI Tech Launches Human Whole Exome Sequencing Service on Complete Genomics' Advanced Platform 2BGI Tech Launches Human Whole Exome Sequencing Service on Complete Genomics' Advanced Platform 3METTLER TOLEDO Shows How Tunable Diode Lasers (TDLs) Can Be Installed Where No TDLs Have Gone Before 2$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 2$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 3$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 4$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 5$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 6$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 7$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 8$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 9$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research 10
... in Second of Two Phase 3 Trials ... - Trial Design Was Reviewed Under Special Protocol Assessment Procedure ... ... SPPI ) today announced today that it has,begun enrolling patients in its second ...
... Prize winner Richard Feynman presented a talk entitled There,s Plenty ... was no physical reason why humans couldn,t manipulate atoms. ... the new atom positions remains. How do you know ... 7, 2007 issue of Science, IBM and Imago have taken ...
... September 11, 2007 - 11:00 a.m. ET; 8:00 a.m. ... /PRNewswire-FirstCall/ - MIGENIX,Inc. (TSX: MGI; OTC: MGIFF), a clinical-stage ... call and webcast on Tuesday,September 11, 2007 at 11:00 ... the first fiscal quarter ended July 31, 2007. An ...
Cached Biology Technology:Spectrum Pharmaceuticals Initiates Second Registrational Phase 3 Clinical Trial for EOquin(R) in Patients With Non-Invasive Bladder Cancer 2Spectrum Pharmaceuticals Initiates Second Registrational Phase 3 Clinical Trial for EOquin(R) in Patients With Non-Invasive Bladder Cancer 3Spectrum Pharmaceuticals Initiates Second Registrational Phase 3 Clinical Trial for EOquin(R) in Patients With Non-Invasive Bladder Cancer 4IBM and Imago find a crucial difficulty in semiconductor device scaling 2MIGENIX First Fiscal Quarter 2008 Financial Results Conference Call & Webcast Notification 2
(Date:7/22/2014)... that mutations in prickle genes cause epilepsy, which ... repeated seizures over time. However, the mechanism responsible ... new University of Iowa study, published online July ... Academy of Sciences , reveals a novel pathway ... identified the basic cellular mechanism that goes awry ...
(Date:7/22/2014)... The Carlton Complex fires started on July 14, 2014, by ... Valley. The Carlton Complex consists of four fires: Stokes Fire, ... The Stokes and Gold Hikes fires are now one larger ... the area burning is currently over 243,000 acres in size. ... to the high fire danger. Public and firefighter safety is ...
(Date:7/22/2014)... as the ,1000 Bull Genomes Project, aims to accelerate ... while also improving animal health and welfare. Results of ... whole genomes of 234 individual bulls whose direct descendants ... in the journal Nature Genetics . , According ... to reduce or eliminate hereditary diseases and to improve ...
Breaking Biology News(10 mins):UI study finds potential genetic link between epilepsy and neurodegenerative disorders 2Whole-genome sequencing of bulls in key beef and dairy breeds 2
... loss of limb control in individuals with spinal cord ... the neural pathways between brain and spinal cord, although ... remain functional. An artificial neural connection that bridges the ... potential to ameliorate the functional loss. Yukio Nishimura, ...
... facing unprecedented threat from climate change, overfishing, pollution, ... Florida researcher is helping coordinate national efforts to ... ocean for food, medicine, transportation and recreation, yet ... spanning 70 percent of the Earth,s surface are ...
... 10, 2013) The ongoing dance between a ... evolves. While human adenoviruses typically cause mild infections, recent ... severe, sometime fatal, human infections. Researchers from ... Provincial Laboratory for Public Health, School of Systems Biology, ...
Cached Biology News:Scientists stress need for national marine biodiversity observation network 2Scientists stress need for national marine biodiversity observation network 3
... Filter Plates are offered in several versions. ... depth filter plates are ideal to prepare ... is simple, versatile, and necessary to prevent ... 10 um glass fiber and 20 um ...
... First-Strand cDNA Labeling Kit with CyScribe ... the generation and purification of Cy3- ... together for complete cDNA labeling and ... used for performing labeling reactions with ...
... CyScribe First-Strand cDNA Labeling System - ... 50 reactions. For the generation and ... reagents are packaged together for complete ... protocols can be used for performing ...
Canine Serum...
Biology Products: