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Reportlinker Adds Upstream Processing in Biopharmaceuticals - Increasing Use of Low-Cost Disposable Bioreactors to Drive the Upstream Bioprocessing Market
Date:3/29/2011

ivers for Outsourcing 44

5.6.6 Restraints to Outsourcing 48

5.7 Upstream Process Market Size 49

5.8 Upstream Process Trends 50

5.8.1 Inclination towards the Transgenic Plant/ Animals 50

5.8.2 R&D and Technology Based Advancements in Upstream Process 52

5.8.3 Focus on Single Use Technology 52

5.9 Upstream Process Drivers 53

5.9.1 Advances in Media and Cell-Line Development will Improve Overall Upstream Process Market 53

5.9.2 Innovations in Transgenic Production Systems will Drive Upstream Process Market in Future 54

5.9.3 Emergence of Newer Technologies Will Improve the Upstream Processing 54

5.10 Upstream Process Restraints 54

5.10.1 R&D Focus has Shifted to Downstream Process 54

5.10.2 High Cost and Time Spent in Upstream Process Affecting Productivity 54

6 Upstream Processing in Biopharmaceuticals – Competitive Landscape 55

6.1 Key Players in the Culture Media and Reagents Market 55

6.1.1 Life Technologies 55

6.1.2 Sigma Aldrich Corporation 57

6.1.3 Millipore Corporation (a Merck KGaA company) 59

6.1.4 Thermo Fisher Scientific 61

6.2 Key CMO Players 63

6.2.1 Lonza Group Ltd (Lonza) 63

6.2.2 Boehringer Ingelheim GmbH (Boehringer) 65

6.2.3 Avecia Biotechnology 67

6.2.4 Diosynth Biotechnology 69

6.2.5 Sandoz GmbH (Sandoz) 71

7 Upstream Processing in Biopharmaceuticals – Technology Landscape 73

7.1 Transgenic Animals (A Live Bioreactor) 73

7.1.1 Transgenic Chickens 74

7.1.2 Proteins from Herd 74

7.2 Transgenic Plants 75

7.2.1 Innovative Technologies 76

7.2.2 Challenges 78

7.2.3 Cell Culture 80

7.3 Single Use Disposable Bioreactors 83

7.3.2 Some Recent Products Developed by Major Firms 84

7.3.3 Challenges 85

7.4 Use of Information Technology to Increase Productivity 86

8 Upstream Process
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