Navigation Links
Reportlinker Adds SNP Genotyping and Analysis Markets
Date:2/9/2010

NEW YORK, Feb. 9 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

SNP Genotyping and Analysis Markets

http://www.reportlinker.com/p0176225/SNP-Genotyping-and-Analysis-Markets.html

Because SNPs (single nucleotide polymorphisms),are the most common type of genetic variation between human beings. These single base pair mutations at specific DNA sequence sites, can be ideal for the task of hunting for correlations between genotype and behavior or quality exhibited by a living organism.

The use of SNP analysis has spread into numerous areas in recent years. But diagnostics and pharmacogenomics are the most promising applications, and market watchers in diagnostics, pharmaceutical, biotechnology and related instrument industries will want to watch developments in SNP analysis closely.

Kalorama Information's analyst Justin Saeks has taken a detailed look into the market for DNA Sequencing Equipment, as well as Gene Expression Profiling Systems. Now, in His report SNP Genotyping and Analysis Markets he looks at SNP analysis instruments, reagents, and related software and services, providing information critical to having an understanding of the business behind this new technology:

  • Overview of SNPs, their Applications and Key SNP Analysis Methods

  • Current Market Size and Estimates of Future Growth

  • Impact of the GWAS 'First Round' on the Market

  • Estimates of Revenues by Region (North America, Europe and ROW) and By Product Type (Consumable, Instruments, Software)

  • Complete List of SNP-Related Deals Made Between Companies Since 2002

  • Exhaustive Review of Products on the Market

  • Market Share of Major Companies in SNP Analysis

  • Discussion of GOLD Database Projects, Government Involvement and Funding

  • Corporate Profiles

  • Regulatory, Technology and Industry Trends as well as;

  • Twelve Challenges the Market Faces and Eight Strategic Recommendations for Companies in the SNP Analysis Market

While the market is expected to create opportunities for growth, the SNP Genotyping and Analysis market is not without its challenges. The report tackles the following trends:

  • Rapid Rate of Product Introductions

  • Increased Multiplexing Creates Improved Products

  • End-Users Attracted to Larger-Scale SNP Platforms

  • Accelerating Discoveries Create Volatile Market

  • Diagnostic Market Holds Obstacles For New Innovations

  • Complexity of Biological Systems Requires Multiple Techniques

  • Miniaturization of Equipment and Instruments

As with all Kalorama Information publications, SNP Genotyping and Analysis Markets is the result of a primary research effort. An analyst with experience following the biotech instrument industry researching all available sources and contacting industry experts and end users to obtain real market insights. Strategic Planners, Marketing Directors, Business Development Executives are among the individuals who will benefit from this resource.

CHAPTER ONE: EXECUTIVE SUMMARY

Introduction

CHAPTER TWO: OVERVIEW

SNP Analysis Methods

Amplification

Allele Discrimination / Assay Reaction Mechanism

Allele-Specific Hybridization

Allele-Specific Invasive Cleavage

Allele-Specific Ligation

Allele-Specific Primer Extension

Allele-Specific Single Base Extension (Single Base Primer Extension)

Single Nucleotide Addition; Pyrosequencing

Assay Format

Detection Method

Definitions

DNA Microarray

Genome-Wide Association

Linkage Analysis

Mass Spectrometry

Single-Nucleotide Polymorphism (SNP)

Applications

Life Science Research

Pharmacogenetics / Pharmacogenomics

Agriculture / Breeding

Case Studies

Case Study #1 - SNPs in Gene for P-glycoprotein Affect Antidepressant Response

Case Study #2 - Celera Studying SNPs Associated With Heart Disease

Case Study #3 - Synonymous SNPs Alter mRNA Splicing with Obesity

Case Study #4 - University of Ottawa Heart Institute (UOHI) Coronary Artery Disease Research

Case Study #5 - Development of Miniaturized Integrated SNP Genotyping Microsystems

CHAPTER THREE: INDUSTRY, TECHNOLOGY, REGULATORY TRENDS

Industry Trends

Period of Limbo While Funding and Content Materialize

Consolidation Occurring in Array and Life Science Markets

Drug and Diagnostics Industries More Comfortable

Broad Acceptance of SNP Analysis' Value

Core Labs Becoming Established Paradigm

Technology Trends

Rapid Rate of Product Introductions

Increased Multiplexing Creates Improved Products

End-Users Attracted to Larger-Scale SNP Platforms

Complexity of Biological Systems Requires Multiple Techniques

Miniaturization of Equipment and Instruments

Regulatory Trends

Introduction

March 2004 - Critical Path Initiative

March 2005 - "Guidance for Industry - Pharmacogenomic Data Submissions"

March 2006 - Critical Path Opportunities

November 2006 - "Recommendations for the Generation and Submission of Genomic Data"

August 2007 - Pharmacogenomic Data Submissions — Companion Guidance

December 2007 - EGAPP Reviews Use of CYP450 Genetic Testing For SSRIs

NIH Limits Access to Data from GWAS

CHAPTER FOUR: PRODUCTS

Affymetrix

Overview

Axiom Genotyping Solution

GeneChip Scanner 3000 7G

GeneChip Scanner 3000 7G Plus Targeted Genotyping System

GeneTitan Multi-Channel (MC) Instrument

Array Station

Microarrays and Reagents

GeneChip Human Mapping 10K Array Xba 142 2.0 (GeneChip Mapping 10K 2.0 Array)

GeneChip Human Mapping 100K Set

Genome-Wide Human SNP Array 5.0

Genome-Wide Human SNP Array 6.0

Axiom Genome-Wide Human Array Plates, Reagent Kits

DMET Plus Premier Pack

GeneChip Universal Tag Arrays and Related Kits

Human 20K cSNP Kit

Human Immune-Inflammation 9K SNP Kit

Human MALD 3K SNP Kit

Bovine Mapping 10K SNP Kit

Bovine Mapping 25K SNP Kit

Rat Mapping 5K SNP Kit

Applied Biosystems (Life Technologies)

Overview

SNP Genotyping Systems and Kits

SNaPshot Multiplex System

SNPlex Genotyping System

TaqMan Genotyping Assays

Applied Biosystems' TaqMan Genotyping Assay Strategy

TaqMan Sample-to-SNP Kits

VariantSEQr Resequencing System

TaqMan OpenArray Genotyping System

7900HT Fast Real-Time PCR System

Sequencers

ABI Prism 310 Genetic Analyzer

ABI Prism 3100-Avant Genetic Analyzer

Applied Biosystems 3100 Genetic Analyzer

Applied Biosystems 3130 Genetic Analyzer

Applied Biosystems 3130xl Genetic Analyzer

Applied Biosystems 3730 DNA Analyzer

Applied Biosystems 3730xl DNA Analyzer

Beckman Coulter

CEQ 8000; CEQ 8800

GenomeLab SNPstream Genotyping Series

CombiMatrix

CustomArray Synthesizer

Geniom RT Analyzer

GE Healthcare

Overview

Reagents and Kits

SNP Genotyping Kits

Sequencers

MegaBACE 500

MegaBACE 750

MegaBACE 1000

MegaBACE 1500

MegaBACE 4000

Illumina

Overview

iScan SQ

BeadXpress Reader

Illumina Genome Analyzer IIx

Microarrays

Human1M-Duo BeadChip

Human1M-Quad BeadChip

LI-COR Biosciences

Roche Applied Science

LightCycler 480 System

HybProbe; SimpleProbe

Sequenom

iPLEX GOLD Assay

MassARRAY System

MassARRAY Compact 96

Selected SNP Genotyping Products & Technologies

CHAPTER FIVE: CONSORTIA, FUNDING, LITIGATION AND DEALS

Consortia, Initiatives

The Cancer Genome Atlas (TCGA) Project

Cancer Sequencing Project

Critical Path Institute (C-Path)

DNA Polymorphism Discovery Resource

Genetic Association Information Network (GAIN)

Genotype-To-Phenotype Database (GEN2PHEN)

International HapMap Project

Introduction & Background

Rationale for HapMap Approach

Process for Producing HapMap

Populations Included in HapMap

Laboratories and Technologies Involved in HapMap

Practical Use of the HapMap Data

MicroArray Quality Control (MAQC) Project

NIH Roadmap

NIH Roadmap for Medical Research

Pharmacogenetics Research Network (PGRN)

Wellcome Trust Case-Control Consortium (WTCCC)

Other Related Initiatives and Consortia

NIH Involvement, Funding for SNPs and Sequencing

Funding for Sequencing Projects Affecting SNP Market

Continued Rapid Growth in Sequence Production

Funding and Consortia for Sequencing

NHGRI Funds Large-Scale Sequencing Centers, 2006

Intellectual Property and Litigation

Patent Interference Between Life Technologies and Pacific Biosciences

Helicos Appeals European Patent Office Decision on Illumina Patent

Applied Biosystems and Illumina Claims and Counter-claims Both Unsuccessful

Fluidigm and Applied Biosystems Agree to End Case

Beckman Coulter and Applied Biosystems Settle Outstanding Legal Disputes

Cepheid and Idaho Technology Settle Dispute Over PCR Patents

Enzo Biochem Disputes CalTech Sequencing Patents

Huang v. CalTech

Applied Biosystems and Amersham plc (GE Healthcare)

Settle Sequencing Patent Litigation

CHAPTER SIX: MARKET ANALYSIS

Historical

Illumina as Bellwether for SNP Analysis Market

Applied Biosystems as Bellwether for RT-PCR Products

Forecast

Assumptions and Scope

Consumer SNP

Product Revenue

Competitive Analysis

CHAPTER SEVEN: CORPORATE PROFILES

Affymetrix

Applied Biosystems (ABI) (Life Technologies)

Illumina

CHAPTER EIGHT: CHALLENGES AND STRATEGIC RECOMMENDATIONS

Challenges

Challenge #1

Challenge #2

Challenge #3

Challenge #4

Challenge #5

Challenge #6

Challenge #7

Challenge #8

Challenge #9

Challenge #10

Challenge #11

Challenge #12

Strategic Recommendations

Recommendation #1

Recommendation #2

Recommendation #3

Recommendation #4

Recommendation #5

Recommendation #6

Recommendation #7

Recommendation #8

TABLE OF EXHIBITS

EXECUTIVE SUMMARY

Figure 1-1: SNP Analysis Market

CHAPTER THREE: INDUSTRY, TECHNOLOGY, REGULATORY TRENDS

Table 3-1 Critical Path Opportunities List

CHAPTER FOUR: PRODUCTS

Table 4-1: Axiom Genome-Wide Array Planes SNP Content

Figure 4-1: TaqMan Assay Strategy

Figure 4-2: Beckman Coulter's SNPstream Assay Strategy

Table 4-2 Selected SNP Products and Technologies.

Figure 4-3 Simple ProbeSequenom

CHAPTER FIVE: CONSORTIA, FUNDING, LITIGATION AND DEALS

Table 5-1: Number of Individuals in Each Subset

Table 5-2: Composition of the DNA Polymorphism Discovery Resources

Figure 5-1: Companies' Technologies Used in First Phase of HapMap

Table 5-3: Technologies Used in Phase 1 of HapMap

Table 5-4: SNP and Sequencing Related Initiatives and Consortia, 2009

Table 5-5: Completely Sequenced Genomes in GOLD, Jan 2009

Figure 5-2 Domains of Completely Sequenced Genomes in GOLD by Year, 1999-2008 and by Category (Archae, Bacteria, Eukaryota)

Figure 5-3 Number of Genome Projects by Inst., '95- Q1 '09 Cumulative

Figure 5-4 Domains of Sequenced Genomes in GOLD, Jan 2009

Table 5-6 Number of Genome Projects by Institution

Figure 5-5 Funding of Genome Projects, 2007-2009 ($M)

Table 5-7: Funding Sources of Genome Projects

Figure 5-6 Human Genome Project Funding, DOE & NIH '90-'03

Table 5-7: Countries Leading Projects, '95-Q1'09

Table 5-8: SNP Projects by Category

Table 5-9: Relevance of Non-Bacterial Sequencing Projects, '95 - Q1 '09, Cum.

Figure 5-7: Disease/Conditions Associated with Projects

Figure 5-8: NHGRI Budget by Year incl. ARRA, 2006-2010 ($M)

Table 5-10: 2010 Est. NHGRI Budget by Mechanism

Figure 5-9 2010 Est. NHGRI Budget by Mechanism

Figure 5-10 NHGRI Funded Large-Scale Sequencing Ctrs '07-'08

Table 5-11 SNP Related Deals, 2009

Table 5-12: SNP Related Patents

CHAPTER SIX: MARKET ANALYSIS

Figure 6-1: Illumina Total Quarterly Revenues, 2003-2009 ($M)

Figure 6-2: Applied Biosystems RT-PCR / Applied Genomics Revenues, 2001-2008 ($M)

Table 6-1: SNP Analysis Tools Market, 2008-2014 ($M)

Figure 6-3: SNP Analysis Tools Market Revenues, 2008-2014 ($M)

Table 6-4: Growth Rate for SNP Analysis Tools

Figure 6-4: SNP Analysis Tools Market Growth Rate, 2008-2014

Figure 6-5: SNP Tools Market by Region (North America, Europe, Japan, ROW)

Table 6-5: SNP Tools Market by Product (Consumable, System, Software/Service)

Figure 6-6: SNP Market by Product, 2008 (Systems, Services/Software, Consumables)

Table 6-6: SNP Analysis Market Shares, 2008 ($M)

Figure 6-7: SNP Analysis Tools Market Shares, 2008 ($M)

CHAPTER SEVEN: CORPORATE PROFILES

Figure 7-1: Affymetrix Revenues by Product Type, 2005 - 2009

Figure 7-2: Affymetrix Consumables Revenues by DNA v RNA

Figure 7-3: Illumina Revenues 2008-2009 by quarter

CHAPTER EIGHT: CHALLENGES AND STRATEGIC RECOMMENDATIONS

Figure 8-1: Cheaper Sequencing Impacts SNP Market

To order this report:

Biotechnology Industry: SNP Genotyping and Analysis Markets

More  Market Research Report

Check our  Company Profile, SWOT and Revenue Analysis!

Nicolas Bombourg

Reportlinker

Email: nbo@reportlinker.com

US: (805)652-2626

Intl: +1 805-652-2626

SOURCE Reportlinker

RELATED LINKS
http://www.Reportlinker.com

'/>"/>

SOURCE Reportlinker
Copyright©2010 PR Newswire.
All rights reserved


Related biology technology :

1. Reportlinker Adds Infectious Disease Molecular Diagnostic Testing
2. Reportlinker Adds Smart Glass: Technologies and Global Markets Report
3. Reportlinker Adds Synthetic Biology: Emerging Global Markets Report
4. Reportlinker Adds Proteomics: Technologies and Global Markets Report
5. Reportlinker Adds Nanomedicine Report
6. Reportlinker Adds Small Molecule Kinase Inhibitors Report
7. Reportlinker Adds Nanoporous Materials Report
8. Reportlinker Adds Membrane Bioreactors Report
9. Reportlinker Adds The Future of Orphan Diseases Therapeutics - Market Forecasts to 2015, Pipeline Analysis and Reimbursement
10. Reportlinker Adds High-Tech Patient Monitoring Systems Markets (Remote and Wireless Systems, Data Processing, EMR Data Transfer) Report
11. Reportlinker Adds In Vitro Diagnostics in a Recession: IVD Market Forecasts, Analysis and Success Strategies Report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... , Germany and ... -- QGEN ; Frankfurt Prime Standard: QIA) ... QIAseq Targeted RNA Panels for gene expression profiling, expanding ... sequencing (NGS). The panels enable researchers to select from ... fold changes and discover interactions between genes, cellular phenotypes ...
(Date:2/11/2016)... , ... February 11, 2016 ... ... publication dedicated to delivering cutting-edge information focused on the development and manufacture ... to become a premier sponsor of the 2016 BioProcess International Awards – ...
(Date:2/11/2016)... , ... February 11, 2016 , ... ... more than 150 years, continues today to pursue the highest level of accuracy ... analytical instruments: the AR9 Refractometer and the AR5 Refractometer. Accurate, reliable and ...
(Date:2/10/2016)... 2016 Early-career researchers from ... , Uganda and Yemen ... and nutrition   Indonesia , Nepal ... and Yemen are being honored for their accomplishments ... also celebrated for mentoring young women scientists who are pursuing careers in ...
Breaking Biology Technology:
(Date:2/1/2016)... 1, 2016  Wocket® smart wallet ( www.wocketwallet.com ) announces the launch ... Joey Fatone . Las Vegas , where Joey ... --> Las Vegas , where Joey appeared at the ... new video ad was filmed at the Consumer Electronics Show (CES2016) in ... booth to meet and greet fans. --> ...
(Date:1/25/2016)... -- Glencoe Software, the world-leading supplier of image data management ... the data management solution OMERO Plus for the newly ... Photo - http://photos.prnewswire.com/prnh/20160125/325328LOGO ... Phenotypic analysis measures the characteristics and behavior of cells, ... such as health and disease, the presence or absence ...
(Date:1/20/2016)... LONDON , Jan. 20, 2016 A ... positioned to directly benefit from the explosion in genomics ... from Howe Sound Research. A range of dynamic trends ... ...... - personalized medicine - pharmacogenomics - pathogen ... economies with large markets - greater understanding of the ...
Breaking Biology News(10 mins):