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Date:3/24/2011

ATIONS 130

TABLE 45 U.S. PATENTS ISSUED ON QD-BIOTECHNOLOGY APPLICATIONS ON SENSOR AND MICRO-ARRAY APPLICATIONS, 2001–2003 131

MORE RECENT DEVELOPMENTS IN BIOLOGICAL APPLICATIONS 131

Commercial Organizations 131

TABLE 46 COMPANIES LEADING QD-BIOTECHNOLOGY/MEDICAL APPLICATIONS BASED ON U.S. PATENT ACTIVITY, 2005–2008 132

TABLE 46 (CONTINUED) 133

TABLE 47 COMPANIES LEADING QD-BIOTECHNOLOGY/MEDICAL APPLICATIONS BASED ON U.S. PATENT ACTIVITY, 2008–OCTOBER 28, 2010 133

TABLE 47 (CONTINUED) 134

Academic Organizations 134

TABLE 48 THE MOST ACTIVE UNIVERSITIES INVOLVED IN QD-BIOTECHNOLOGY APPLICATIONS ACCORDING TO U.S. PATENTS ISSUED, 2005–2007 135

TABLE 49 LEADING UNIVERSITIES AND HOSPITALS INVOLVED IN QD-BIO/MEDICAL APPLICATIONS ACCORDING TO U.S. PATENTS, 2008—OCTOBER 28, 2010 136

TABLE 49 (CONTINUED) 137

COMPANY PROFILES—BIOLOGICAL APPLICATIONS 137

Affymetrix, Inc. 137

Amnis Corporation 138

Applera Corporation 138

Biocrystal Ltd. 139

Clinical Micro Sensors, Inc./Osmetech Molecular Diagnostics 140

Clontech Laboratories, Inc. 141

Genoptix, Inc. 141

Helicos BioSciences Corporation 142

Illumina, Inc. 142

Intel Corporation 143

Integrated Raman Bioanalyzer System 144

MEMS-Based Hydrodynamic Focusing 145

LI-COR Incorporated 145

Luminex Corporation 146

Nanosphere, Inc. 146

Pharmaceutical Product Development, Inc. 147

U.S. Genomics, Inc. 147

BIOMEDICINE 148

DEVELOPMENTS IN BIOMEDICAL APPLICATIONS 148

TABLE 50 QD MEDICAL APPLICATIONS DERIVED FROM U.S. PATENTS: 2000–2004 149

TABLE 50 (CONTINUED) 150

MORE RECENT DEVELOPMENTS IN BIOMEDICAL APPLICATIONS 150

TABLE 51 QD MEDICAL APPLICATIONS DERIVED FROM U.S. PATENTS, 2005–2007 151

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