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Reportlinker Adds Proteomics - Technologies, Markets and Companies

Table 6 1: Pharmaceutical applications of proteomics143

Table 6 2: Selected companies relevant to MALDI-MS for drug discovery151

Table 6 3: Selected companies involved in GPCR-based drug discovery157

Table 6 4: Companies involved in drug design based on structural proteomics164

Table 6 5: Proteomic companies with high-throughput protein expression technologies171

Table 6 6: Selected companies involved in chemogenomics/chemoproteomics181

Table 6 7: Companies involved in glycoproteomic technologies186

Table 7 1: Applications of proteomics in human healthcare199

Table 7 2: Companies involved in applications of proteomics to oncology239

Table 7 3: Neurodegenerative diseases with underlying protein abnormality244

Table 7 4: Disease-specific proteins in the cerebrospinal fluid of patients253

Table 7 5: Eye disorders and proteomic approaches265

Table 8 1: Potential markets for proteomic technologies 2009-2019269

Table 8 2: Geographical distribution of markets for proteomic technologies 2009-2019270

Table 8 3: 2009 revenues of major companies from protein separation technologies270

Table 9 1: Role of proteomics in personalizing strategies for cancer therapy298

FiguresFigure 1 1: A schematic miRNA pathway20

Figure 1 2: Relationship of DNA, RNA and protein in the cell26

Figure 1 3: Protein production pathway from gene expression to functional protein with controls.28

Figure 1 4: Parallels between functional genomics and proteomics29

Figure 2 1: Proteomics: flow from sample preparation to characterization36

Figure 2 2: The central role of spectrometry in proteomics42

Figure 2 3: Electrospray ionization (ESI)43

Figure 2 4: Matrix-Assisted Laser Desorption/Ionization (MALDI)44

Figure 2 5: Scheme of bio-bar-code assay59

Figure 2 6: A diagrammatic presentation of yeast two-hybrid system67

Figure 3 1

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