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Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment
Date:10/26/2009

Synageva BioPharma

Alternative Modes of Administration

Altus Pharmaceuticals

Baxter BioPharma Solutions

Chapter 3

MARKETED AND EMERGING MONOCLONAL

ANTIBODIES: PRESENT AND FUTURE

THERAPEUTICS

3.1. Approved Therapeutic Monoclonal Antibodies

Profiles of Therapeutic Monoclonal Antibodies Approved for

Marketing

Orthoclone OKT3 (Muromonab-CD3) (1986)

ReoPro (Abciximab) (1994)

Rituxan (Rituximab) (1997)

Zenapax (Daclizumab) (1997)

Simulect (Basiliximab) (1998)

Synagis (Palivizumab) (1998)

Remicade (Infliximab) (1998)

Herceptin (Trastuzumab) (1998)

Mylotarg (Gemtuzumab Ozogamicin) (2000)

Campath (Alemtuzumab) (2001)

Zevalin (Ibritumomab Tiuxetan) (2002)

Humira (Adalimumab) (2002)

Xolair (Omalizumab) (2003)

Bexxar (Tositumomab) (2003)

Raptiva (Efalizumab) (2003)

Erbitux (Cetuximab) (2004)

Avastin (Bevacizumab) (2004)

Tysabri (Natalizumab) (2006)

Lucentis (Ranibizumab) (2006)

Vectibix (Panitumumab) (2006)

Soliris (Eculizumab) (2007)

Cimzia (Certolizumab Pegol) (2008)

Ilaris (Canakinumab) (2009)

3.2. Monoclonal Antibodies in Development for Cancer

Unconjugated Monoclonal Antibodies for Cancer

Biogen Idec

Genentech

Human Genome Sciences

Immunomedics

ImClone Systems (Eli Lilly)

Morphotek (Eisai Corp. of North America)

Antisoma

Micromet

AVEO Pharmaceuticals

Northwest Biotherapeutics

Anti-idiotype Monoclonal Antibodies for Cancer

Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment

Menarini Group

Conjugated Mono
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