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Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment

Synageva BioPharma

Alternative Modes of Administration

Altus Pharmaceuticals

Baxter BioPharma Solutions

Chapter 3




3.1. Approved Therapeutic Monoclonal Antibodies

Profiles of Therapeutic Monoclonal Antibodies Approved for


Orthoclone OKT3 (Muromonab-CD3) (1986)

ReoPro (Abciximab) (1994)

Rituxan (Rituximab) (1997)

Zenapax (Daclizumab) (1997)

Simulect (Basiliximab) (1998)

Synagis (Palivizumab) (1998)

Remicade (Infliximab) (1998)

Herceptin (Trastuzumab) (1998)

Mylotarg (Gemtuzumab Ozogamicin) (2000)

Campath (Alemtuzumab) (2001)

Zevalin (Ibritumomab Tiuxetan) (2002)

Humira (Adalimumab) (2002)

Xolair (Omalizumab) (2003)

Bexxar (Tositumomab) (2003)

Raptiva (Efalizumab) (2003)

Erbitux (Cetuximab) (2004)

Avastin (Bevacizumab) (2004)

Tysabri (Natalizumab) (2006)

Lucentis (Ranibizumab) (2006)

Vectibix (Panitumumab) (2006)

Soliris (Eculizumab) (2007)

Cimzia (Certolizumab Pegol) (2008)

Ilaris (Canakinumab) (2009)

3.2. Monoclonal Antibodies in Development for Cancer

Unconjugated Monoclonal Antibodies for Cancer

Biogen Idec


Human Genome Sciences


ImClone Systems (Eli Lilly)

Morphotek (Eisai Corp. of North America)



AVEO Pharmaceuticals

Northwest Biotherapeutics

Anti-idiotype Monoclonal Antibodies for Cancer

Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment

Menarini Group

Conjugated Mono

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