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Reportlinker Adds Biomarkers - Technologies, Markets And Companies

stage of drug discovery and development . 113

Drug development in cardiovascular disorders . 114

Drug development in neurological disorders . 114

Future prospects of biomarker-based drug development .. 115

The Biomarker Alliance . 115

Molecular Libraries and Imaging Roadmap of NIH 115

Biomarkers Consortium 116

Pharmacogenomic biomarker information in drug labels . 117

5. Role of Biomarkers in Healthcare . 118

Introduction .. 118

Biomarkers of inflammation 118

ESR and CRP as biomarkers of inflammation 119

Biomarkers of oxidative stress . 119

1,4-dihydroxynonane-mercapturic acid .. 119

Oxidative DNA damage 120

Proteins as biomarkers of oxidative stress in diseases .. 120

Testing for oxidative stress 120

Biomarkers in metabolic disorders.. 120

Biomarkers of acute intermittent porphyria .. 120

Liver X receptors .. 121

Biomarkers of diabetes mellitus 121

Biomarkers of hyperglycemia . 122

Biomarkers of diabetes-associated oxidative stress . 122

Biomarkers of inflammation associated with diabetes . 123

Biomarkers of renal complications in diabetes mellitus type 2 .. 123

Biomarkers of diabesity 123

Glycosylated hemoglobin in diabetes mellitus 123

Lack of C-peptide as biomarker of complications of diabetes type 1 123

Serum retinol binding protein 4 as biomarker of insulin resistance . 124

Biomarkers of metabolic syndrome . 124

Adiponectin .. 124

Biomarkers in immune disorders . 125

Biomarkers relevant to organ transplantation .. 125

Biomarkers of graft versus host disease .. 125

Biomarkers of renal allograft failure .. 127

Biomarkers of renal transplant tolerance . 128

Biomarkers of lung transplant rejection .. 128

Systemic lupus erythematosus . 129

Current management and nee

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