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Reportlinker Adds Biomarkers - Technologies, Markets And Companies
Date:11/9/2010

ering biomarkers . 77

Nanosensors for measuring biomarkers in blood 78

Nanobiochip sensor technique for analysis of oral cancer biomarkers .. 78

Nucleoprotein nanodevices for detection of cancer biomarkers .. 78 - 5 -

Future prospects of application of nanobiotechnology for biomarkers .. 79

Bioinformatics . 79

Biomarker Workflow Guide 79

Analysis of microarray data for selecting useful biomarkers 80

Role of bioinformatics in discovery of protein biomarkers 80

Role of bioinformatics in detection of cancer biomarkers . 81

Biomarker databases .. 81

Gene networks as biomarkers .. 81

3. Biomarkers and Molecular Diagnostics . 84

Introduction . 84

Molecular diagnostic technologies . 84

Polymerase chain reaction . 84

Amplification .. 84

Target selection . 85

Detection of amplified DNA . 85

Limitations of PCR . 85

Real-time PCR systems .. 86

Limitations of real-time PCR .. 86

Future applications of real-time Q-PCR .. 87

Combined PCR-ELISA . 87

Non-PCR methods 87

Linked Linear Amplification . 88

Transcription mediated amplification . 88

Rapid analysis of gene expression .. 88

WAVE nucleic acid fragment analysis system .. 88

DNA probes with conjugated minor groove binder . 89

Rolling circle amplification technology 89

Gene-based diagnostics through RCAT 90

RCAT-immunodiagnostics 90

RCAT-biochips 91

RCAT-pharmacogenomics .. 91

Circle-to-circle amplification . 91

Biochips and microarrays .. 91

Applications of biochips/microarrays 92

Role of biochip/microarrays in discovery of biomarkers . 92

Biomarkers and high throughput molecular screening . 93

Detection and expression profiling of miRNA 93

Real-time PCR for expression profiling of miRNAs .. 94

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