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Reportlinker Adds Biomarkers - Technologies, Markets And Companies
Date:11/9/2010

s and pharmacoproteomics for development of personalized medicine.

Many of the regulatory issues concerning biomarkers are related to genomics, proteomics, molecular diagnostics and pharmacogenomics/pharmacogenetics. Validation of biomarkers and their role in clinical trials is discussed.

Biomarker markets are estimated from 2009 to 2019 according to share of markets for various technologies and applications: proteomics, metabolomics, molecular diagnostics, drug discovery, clinical trials, and bioinformatics. Market values are further split according to therapeutic applications and major geographical areas. Unfulfilled needs in biomarkers are identified as well as the drivers for biomarker markets. Challenges facing the biomarker industry and strategies for developing biomarker markets are discussed.

A large number of companies with varying technical backgrounds are involved in biomarkers and 267 of these are profiled in part 2 of the report with classification into various categories. These also include major pharmaceutical companies. There is tabulation of 481 collaborations between companies and additional academic collaborations are mentioned in the individual profiles of companies. The report is supplemented by 800 references, 62 tables and 12 figures

TABLE OF CONTENTS

0. Executive Summary 20

1. Introduction .. 22

Definitions . 22

Historical aspects of biomarkers . 22

Classification of biomarkers .. 23

Biological marker as response to therapeutic intervention .. 24

Pharmacokinetic/pharmacodynamics biomarkers .. 24

Predictive biomarkers . 24

Valid biomarkers .. 25

Types of biomarkers . 25

Genes as biomarkers .. 25

Proteins as biomarkers .. 26

Proteomics .. 26

DNA biomarkers .. 27

Mitochondrial DNA .. 27

Mitochondrial mutations .. 27

RNA biomarkers 27

Transcriptomics . 28

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