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Date:11/9/2010

H13 gene as a biomarker of cancer 282

Serum-protein fingerprinting .. 282

Tests for prostate cancer based on genetic dislocations . 282

Concluding remarks on biomarkers of prostate cancer 283

Renal cancer biomarkers . 283

Gene expression profile of RCC for biomarkers . 283

miRNA biomarkers of renal cancer 283

Use of proteomics for detection of RCC biomarkers . 284

Use of RCC biomarkers for prognosis and therapy 284

Thyroid cancer biomarkers . 285

Gene expression biomarkers of thyroid cancer .. 285

Multiple endocrine neoplasia type 2B as risk factor for thyroid cancer 286

miRNA biomarkers of thyroid cancer . 286

Biochemical biomarkers of thyroid cancer .. 286

Role of the NCI in molecular diagnosis of cancer . 286

The Cancer Genome Anatomy Project . 287

Molecular profiling of cancer .. 287

Cancer Genome Atlas .. 287

Cancer Genetic Markers of Susceptibility Project . 288

Oncology Biomarker Qualification Initiative .. 288

Role of NCI in cancer biomarker development and validation .. 289

COBRED project for cancer biomarker research in Europe .. 290

Future prospects for cancer biomarkers .. 291 - 12 -

Cancer biomarker research at academic institutions .. 291

Future prospects and challenges in the discovery of cancer biomarkers .. 291

7. Biomarkers of Disorders of the Nervous System 294

Introduction .. 294

Discovery of biomarkers for neurological disorders 294

Biomarker identification in the CSF using proteomics . 295

Biomarker identification in the CSF using lipidomics .. 295

Cerebral microdialysis for the study of biomarkers of cerebral metabolism . 295

Detection of protein biomarkers of CNS disorders in the blood 296

Brain imaging for detection of biomarkers . 296

Biomarkers of the aging brain .. 297

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