Navigation Links
Replikins Oral Vaccine Synthesized in 7 Days Protects 91% of Shrimp Against a Lethal Virus
Date:3/11/2008

BOSTON, March 11 /PRNewswire/ -- Replikins, Ltd. has announced development of a chemically synthesized vaccine specific to a Taura Syndrome virus structure based on its patented Replikins(TM) technology. When the vaccine was administered orally to shrimp, 91% survived a challenge by the lethal Taura virus. The specificity of the protective effect was established in control groups by chemically blocking the active regions in the vaccine, and as a result the protective effect was lost in these control groups. The effectiveness of this vaccine, and its rapid production cycle (7 days), represent an important proof of concept for developing vaccines against a range of rapidly replicating high lethality virus outbreaks.

For counteracting emerging infectious disease, early detection and rapid response are critical. Replikin contributions to date are both in early detection and rapid response: 1) Advance warning previously was not possible until it was found in H5N1 influenza that an increase in the virus replikin concentration signalled one year in advance that the outbreak was coming, and indicated the country in which this would occur (FluForecast(TM), Indonesia). 2) The production of vaccines by other methods has required 3 to 12 months, by which time the epidemic may have come and gone, or the vaccine effectiveness reduced or lost because the target changed due to mutation. In contrast, the replikins vaccine found effective here was manufactured synthetically in 7 days.

Viruses lethal to shrimp have been responsible for large losses to aquaculture worldwide. Replikins is forming a division to focus on these viruses. The company is also pursuing development of synthetic vaccine products based on replikin epitopes, Syntopes(TM), for the control of fish hemorrhagic viruses and other lethal aquatic microorganisms,

Contact: Replikins Ltd., 38 The Fenway, Boston MA 02215. email: sbogoch@replikins.com Tel: 646-320-5910

SOURCE Replikins Ltd.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. John E. Leonard, Ph.D., Former Biogen Idec Antibody Development Executive, Joins the Scientific Advisory Board of Vaccinex, Inc.
2. Vaccinogens New Anti-Cancer Vaccine Commercially Available in Europe This Year
3. Childhood Influenza Immunization Coalition Applauds Expanded Influenza Vaccine Recommendation for Children
4. Combination vaccine protects monkeys from ebola and Marburg viruses
5. Nasal Vaccine for Smallpox Confers High Levels of Immunity Without Safety Risks
6. Vaccines are Likely to Cause Insulin Dependent Diabetes in Over 2% of Children With a Strong Family History of Insulin Dependent Diabetes, New Data Indicates
7. GSK Receives Favorable Recommendation by FDA Advisory Committee for Rotarix(R) (Rotavirus Vaccine, Live, Oral)
8. ImmunoVaccine Technologies appoints the Honourable Michael Kirby as Chair
9. Vaccinex Antibody Licensed to GlaxoSmithKline
10. Carrington Subsidiary DelSite Starts Making Test Batches of First Bird Flu Vaccine Offering Needle-free Self-Administration
11. NIH Funds Vaccine Research for Needle-free and Self-Administered Protection Against Pandemic Influenza
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Two champions of science, technology, engineering, and mathematics ... competition for middle and high school students designed to ... The competition presents students with real-world problems experienced by ... and Sciences is a program administered by the ...
(Date:1/15/2014)... 15, 2014 AudioNotch is the internet's ... for the treatment of tinnitus. Patients listen to sound ... over a period of weeks to months, their tinnitus volume ... two forms: Notched Music and Notched White Noise. Now, AudioNotch ...
(Date:1/14/2014)... Communications, a leading provider of strategic communications services to corporations and ... the United States and Europe ... JD, is returning to the firm,s Washington, D.C. ... more than two years of service as Associate Commissioner for the ...
(Date:1/14/2014)... 14, 2014 iLab Solutions, the leader in ... new Director of Product Strategy. In this role, Michelle will ... sub-teams to guide in the development of iLab products. Her ... maximum possible benefit to the scientific community by offering the ...
Breaking Biology Technology:Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Former FDA Associate Commissioner Returns To 3D Communications 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... of Technologies for Enabling Faster, Easier,Quantification of Protein Biomarkers in ... ... Clinical Trials, WALTHAM, Mass., Dec. 10 Decision ... for,pharmaceutical research and development, today announced the company,s,PATH(R) technology has ...
... N.H., Dec. 10 iCAD, Inc. (Nasdaq:,ICAD), an ... early identification of cancer, today announced that two,U.S. ... been granted,to the Company by the United States ... demonstrate our on-going commitment to broadening,and protecting our ...
... clinic ... TSX Exchange Symbol: RVX, CALGARY, Dec. 10 /PRNewswire-FirstCall/ ... by,the US Food and Drug Administration (FDA) to initiate a Phase ... novel first-in-class small,molecule that increases the production of ApoA-I and HDL. ...
Cached Biology Technology:Decision Biomarkers Awarded U.S. Patent for Protein Array Surface Chemistry 2iCAD, Inc. Awarded Two Additional Patents for Its Computer-Aided Detection Technology 2iCAD, Inc. Awarded Two Additional Patents for Its Computer-Aided Detection Technology 3FDA Grants Resverlogix Approval to Commence a Phase 1 Clinical Trial for RVX-208 2FDA Grants Resverlogix Approval to Commence a Phase 1 Clinical Trial for RVX-208 3
(Date:4/16/2014)... improves during childhood, associated with structural changes in the ... New research from UC Davis is exploring how these ... could give insights into disorders that typically emerge in ... such as schizophrenia and depression. , Located deep in ...
(Date:4/16/2014)... Geologic and soil processes are to blame for significant ... a study published recently in the Journal of Environmental ... all corners of Ohio showed that every single sample had ... the U.S. Environmental Protection Agency. The findings should not alarm ...
(Date:4/16/2014)... , A research group composed of Dr. Martin Prechtl, ... Cologne,s Department of Chemistry has discovered a new method ... of hydrogen from liquids is of particular interest when ... the project, entitled "Selective and mild hydrogen production using ...
Breaking Biology News(10 mins):How kids' brain structures grow as memory develops 2Significant baseline levels of arsenic found in Ohio soils are due to natural processes 2Significant baseline levels of arsenic found in Ohio soils are due to natural processes 3Significant baseline levels of arsenic found in Ohio soils are due to natural processes 4
... Illinois researchers, Phillip A. Newmark, a professor of cell ... the William H. and Janet Lycan professor of chemistry, ... Newmark and van der Donk are among 56 biomedical ... nationwide competition. The 2008 investigators were selected for their ...
... The University of Nottingham have taken some important first ... cell, a leading science journal reports. Dr Cameron ... School of Pharmacy have used polymers long-chain molecules ... the surfaces of a real cell. In work ...
... summer temperatures could mean some parts of southern England are ... according to a new book launched today (26 May 2008). ... College London, claims that if average summer temperatures in the ... of Hampshire and the Severn valley, which currently contain many ...
Cached Biology News:2 University of Illinois researchers named HHMI investigators 22 University of Illinois researchers named HHMI investigators 3Life, but not as we know it? 2Research suggests parts of UK could be too hot for wine making by 2080 2
CHIMAERIC HUMAN IgA2 ANTI NP...
ANTI NO-TRYPTOPHAN CONJUGATE...
... Captivate magnetic separator for 96-well ... in conjunction with the Captivate ... or other magnetic particles and ... microplates. Cell Biology Cell Separation ...
Protein Phosphorylation...
Biology Products: