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Repligen Reports First Quarter Fiscal Year 2010 Financial Results
Date:8/6/2009

Protein A, the sales of which partially fund the advancement of our development pipeline while supporting our financial stability. Repligen's corporate headquarters are located at 41 Seyon Street, Building #1, Suite 100, Waltham, MA 02453. Additional information may be requested from www.repligen.com.

                             REPLIGEN CORPORATION
                           STATEMENTS OF OPERATIONS
                                 (Unaudited)

                                             Three months ended June 30,
                                             ---------------------------
                                                 2009            2008
                                                 ----            ----
    Revenue:
      Product revenue                         $2,472,590      $5,693,343
      Royalty and other revenue                2,588,263       7,966,902
                                               ---------       ---------
        Total revenue                          5,060,853      13,660,245

    Operating expenses:
      Cost of product revenue                  1,270,474       1,846,401
      Cost of royalty and other revenue          317,745         325,000
      Research and development                 3,383,000       2,084,125
      Selling, general and administrative      1,517,357       1,446,571
        Total operating expenses               6,488,576       5,702,097
                                               ---------       ---------

    Income (loss) from operations             (1,427,723)      7,958,148
    Investment income                            322,419         532,585
    Interest expense                                (676)         (1,905)
                                                    ----          ------
    Income (loss) before income taxes         (1,105,980)      8,488,828
    Income tax (b
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