Navigation Links
Regulus Therapeutics and Collaborators Publish New Pre-Clinical Data on microRNA-33 Demonstrating Key Role in Cholesterol Homeostasis and Fatty Acid Metabolism
Date:10/20/2011

umulation of triglycerides (Davalos et al., PNAS. 2011).  These findings indicate that miR-33a and miR-33b are key regulators of cholesterol and fatty acid metabolism, and that an anti-miR-33 approach can directly impact atherosclerosis, as well as address important cardiovascular risk factors such as obesity, insulin resistance, and hypertriglyceridemia.

Regulus is developing microRNA therapeutics targeting miR-33a/b. The company controls fundamental patent rights related to miR-33a/b, including the miR-33a/b sequence and complementary sequences covered in the Tuschl III patent series. Additional Regulus patent rights include compositions of matter for various chemically modified anti-miR-33a/b compounds and methods of use for the treatment of cardiovascular diseases with anti-miR-33a/b.  

Webinar to be held on October 26, 2011

Dr. Moore and Regulus scientists, Drs. Neil Gibson, Ph.D., Chief Scientific Officer, Hubert Chen, M.D., and Christine Esau, Ph.D., Associate Director Metabolic Disease, will present the data published in Nature and discuss the data's implications in a webinar scheduled for 11:00am EDT on October 26, 2011. To participate in the webinar, register at http://www.videonewswire.com/event.asp?id=82015. Please connect to the webinar several minutes prior to the start time to ensure adequate time for any software download that may be necessary. Questions for the panelists may be submitted during the live event through the web portal. The webinar will be available for replay on the Regulus website at http://www.regulusrx.com.

About microRNA-33a/b

microRNA-33a and b (miR-33a/b), which differ by only two nucleotides, are intronic microRNAs located  within the sterol response elemen
'/>"/>

SOURCE Regulus Therapeutics Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related biology technology :

1. Regulus Therapeutics and GlaxoSmithKline Name a Third Alliance microRNA Target Triggering a Preclinical Milestone Payment
2. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
3. United Therapeutics Corporation to Announce Third Quarter 2011 Financial Results Before Market Open on Thursday, October 27, 2011
4. Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018
5. Influenza Vaccines Therapeutics - Pipeline Assessment and Market Forecasts to 2018
6. ReportsnReports: Depression Therapeutics Market to Reach $10.9 Billion by 2018
7. Shield Therapeutics Initiates AEGIS 1 and AEGIS 2 Phase 3 Studies of ST10
8. United Therapeutics Announces Proposed Private Offering of $210 Million of Convertible Senior Notes and Authorization of Stock Repurchase Program
9. United Therapeutics Subsidiary Enters Into Contract With National Institutes of Health for Award of up to $45 Million to Support Glycobiology Antiviral Program
10. Kylin Therapeutics Receives Notice of Allowance for Second U.S. Patent Covering Delivery of Therapeutic RNA and pRNAi Technology
11. Orexigen® Therapeutics Announces Multiple Contrave® Data Presentations at the 29th Annual Scientific Meeting of The Obesity Society
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... 2014 According to the new ... Analytics (Image Analysis Software), Delivery Modes (Web Based/Cloud Based) ... Trends to 2018", published by MarketsandMarkets, analyzes and studies ... as North America , ... the Rest of the World (RoW). Browse ...
(Date:7/29/2014)... Colo. , July 29, 2014  Cannabis ... in cannabis formulation-based drug development and related consulting, ... Times for taking a strong position in opposition ... Sunday, July 27, 2014 publication.  The New York ... and articles this week exploring the issue called ...
(Date:7/29/2014)... 29, 2014 Philadelphia’s newest entrepreneurial incubation space ... their start. The Innovation Center @3401 , a collaborative ... City Science Center to help attract and nurture start-up ... July 28. , The Innovation Center @3401 ... Market Streets, is the new home of DreamIt Ventures ...
(Date:7/29/2014)... 2014 Quorum Review IRB, the ... awarded accreditation by the International Association of ... Six Sigma Deployment Program. The citation recognizes robust ... , Quorum’s Lean Six Sigma program was evaluated ... designation. The designation is a public statement of ...
Breaking Biology Technology:Digital Pathology Market worth $437 Million by 2018 2Digital Pathology Market worth $437 Million by 2018 3Cannabis Science, Inc. (CBIS) Applauds New York Times Editorial Board Stance on 'Repealing Prohibition, Again'; NYT Editorial Is Bell Weather of Change 2Cannabis Science, Inc. (CBIS) Applauds New York Times Editorial Board Stance on 'Repealing Prohibition, Again'; NYT Editorial Is Bell Weather of Change 3Innovation Center @3401 Opens for Business; DreamIt Ventures and Point.io First Residents 2Innovation Center @3401 Opens for Business; DreamIt Ventures and Point.io First Residents 3Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 2Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 3
... N.J., Aug. 11, 2011 Insmed Incorporated (Nasdaq CM: ... President and CEO of Insmed, will be presenting a ... Management Access Conference on Tuesday, August 16, 2011, at ... live audio webcast will be available on the Investors ...
... 11, 2011 Cellular Dynamics International (CDI) announced today ... This grant program will advance researchers, understanding of induced ... from them, and the role and applications of this ... discovery and development.   "The off-the-shelf availability ...
... LONDON, August 11, 2011 Pharma IQ is pioneering ... compound management event - Compound Management and Integrity Online ... over the course of 5 weeks, beginning 31 ... compound management and integrity process is high on the agenda for ...
Cached Biology Technology:Insmed to Present at 2011 Wedbush Securities Life Sciences Management Access Conference 2Cellular Dynamics Launches Innovative Research Grant Program 2Compound Management and Integrity Goes Online 2Compound Management and Integrity Goes Online 3
(Date:7/29/2014)... warms and sea ice retreats, the North is changing. ... open water which is predicted to extend across the ... Storms thus have the potential to create Arctic swell ... unpredictable element to the region. , A University of Washington ... middle of the Arctic Ocean, and detected house-sized waves ...
(Date:7/29/2014)... microorganisms, such as bacteria and spermatozoa, are subjected to ... exerted by the surrounding fluid. Such low-level inertia ... that the direction of propulsion made possible by such ... fluid. These findings have been published in EPJ ... and Atomic Energy Commission (CEA), in Le Barp, France, ...
(Date:7/29/2014)... been plaguing the Northern Territories in Canada and have ... the U.S. continue on. NASA,s Aqua satellite collected ... MODIS, instrument on July 26, 2014. Actively burning areas, ... Copious amount of smoke are drifting northward in this ... of Yellowknife. Fire has caused power outages in ...
Breaking Biology News(10 mins):Huge waves measured for first time in Arctic Ocean 2Huge waves measured for first time in Arctic Ocean 3Optimum inertial self-propulsion design for snowman-like nanorobot 2
... has awarded $11.5 million to a consortium of research ... for the creation of a center for the study ... the X-ray Structure Determination of Human Transportersis one of ... "solve the structures of these elusive yet very medically ...
... UCLA has received a five-year, $12.5 million contract award from ... international consortium of medical experts that will study proteins that ... Heart disease is a leading killer worldwide, but ... or how the inner sub-units of a cardiac cell work ...
... scientists suggests that a class of material known as metallacarborane ... the United States Department of Energy (DOE) Hydrogen Program for ... comes into play as a fuel of the future for ... study by Rice theoretical physicist Boris Yakobson and his colleagues, ...
Cached Biology News:NIH awards $11.5 million for new Caltech-led membrane-protein center 2UCLA receives $12.5M to lead international project to study proteins implicated in heart disease 2Hydrogen fuel for thought 2
... The Label IT siRNA Tracker Intracellular Localization ... directly label and deliver siRNA, of your ... for in vitro tracking experiments. Subcellular localization ... can be monitored following introduction of the ...
... The Label IT siRNA Tracker Intracellular ... provides a straight forward approach to ... your design, in an efficient yet ... experiments. Subcellular localization and functional inhibition ...
... and reproducible immunoprecipitation (IP) by using a 96 ... than regular IPs, which are problematic with regards ... the agarose bed. The binding of the antibody/antigen ... elution of the immune complex can occur with ...
... The Yeast Oligo Microarray Kit (V2), ... to simultaneously characterize expression of many ... gene activity during important biological processes. ... representing 6,256 known ORFs from the ...
Biology Products: