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Regulus Receives Allowance from Japan and U.S. Patent Offices for HCV Intellectual Property, Expanding Leading Worldwide Patent Estate
Date:4/23/2012

LA JOLLA, Calif., April 23, 2012 /PRNewswire/ -- Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that the Japan Patent Office has issued a Decision to Grant a Patent in the 'Sarnow' patent series for microRNA-122 (miR-122) therapy in the treatment of chronic hepatitis C virus (HCV) infection. The Sarnow patent estate, owned by Stanford University and exclusively licensed to Regulus, has already produced patents in Australia, Europe and the United States, and covers the use of a broad class of anti-miR inhibitors of miR-122 for the treatment of HCV.  

Regulus also announced today that the U.S. Patent and Trademark Office has allowed claims in a third Sarnow patent application, relating to the use of anti-miR-122 agents as monotherapy or in combination with other anti-viral therapies, to treat HCV-infected patients. 

"The recent allowance of miR-122 therapy claims further broadens Regulus' dominant and comprehensive intellectual property estate covering microRNA therapeutics," said Kleanthis G. Xanthopoulos, Ph.D., President and CEO of Regulus Therapeutics Inc.  "The HCV landscape continues to be a dynamic and ever-evolving space, with improvements upon direct-acting antiviral therapy on the horizon.  We believe anti-miR-122 is attractively positioned for use in combination with direct-acting antivirals to further reduce viral load and suppress viral resistance."

Regulus' Patent Estate for Anti-miR-122 Therapeutic Agents

Regulus controls a comprehensive and dominant patent estate related to microRNA therapeutics, including anti-miR-122 therapeutic agents. Specifically for miR-122, Regulus controls the following:

  • The 'Sarnow' patent estate claiming the use of an anti-miR-122 to treat HCV, as a single ther
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SOURCE Regulus Therapeutics Inc.
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