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Regado Biosciences Establishes Medical Advisory Board
Date:6/2/2009

ector of Coronary Care and Green Lane Cardiovascular Research Unit, Auckland City Hospital, Auckland, New Zealand

About Regado Biosciences, Inc.

Regado Biosciences is pioneering a new therapeutic technology with the creation and development of two-component drug systems. Each system is comprised of a nuclease-stabilized RNA aptamer therapeutic that can be controlled directly by its specific and complementary oligonucleotide active control agent. This technology is being applied initially to acute care injectable antithrombotics, a multi-billion dollar market in need of therapeutics with improved safety profiles and a greater degree of therapeutic control. Regado's technology is designed to give physicians the ability to actively and directly control each system's therapeutic effect providing a safe and unique approach to personalized medicine.

Regado's lead program, REG1, is comprised of two parenteral agents, the first being a potent and highly selective Factor IXa inhibitor (RB006) and the second being its complementary active control agent (RB007). RB007 can be used to completely or partially reverse the anticoagulant effect of RB006. Regado recently completed a phase 2a study of REG1 in percutaneous coronary intervention (PCI) and is planning the initiation of a rigorous phase 2b program in this same indication in 3Q2009.

More information can be found at http://www.regadobio.com


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