Navigation Links
Regado Biosciences Announces Allowance in Europe of a Fundamental Patent Broadly Covering Oligonucleotide Modulators to Blood Coagulation Factor Aptamers
Date:9/17/2009

ms. Each system comprises a nuclease-stabilized RNA aptamer that can be controlled directly by its specific and complementary oligonucleotide active control agent. This technology is being applied to injectable antithrombotics, including anticoagulants and antiplatelet agents, a multi-billion dollar market in need of therapeutics with improved safety profiles and a greater degree of therapeutic control. Regado's technology is designed to give physicians the ability to actively and directly control each system's therapeutic effect providing a safe and unique approach to personalized medicine.

ABOUT REG1 and REG2

Regado's lead program, the anticoagulant system REG1, consists of two parenteral agents both administered by IV bolus, the first being a potent highly selective Factor IXa inhibitor (RB006) and the second being its complementary active control agent (RB007). RB007 can be used to selectively completely or partially reverse the anticoagulant effect of RB006. REG1 is intended for application in arterial thrombosis applications, initially in Acute Coronary Syndrome patients undergoing Percutaneous Coronary Intervention. REG2, Regado's second product candidate, consists of a subcutaneously administered formulation of RB006 paired with the IV bolus formulation of RB007. REG2 is intended for use in venous thrombosis indications

ABOUT APTAMERS

RB006 is a member of a class of compounds called aptamers. Aptamers are single stranded oligonucleotides that adopt a specific conformation enabling direct, specific inhibition of the targeted protein. A key unique feature of aptamers derives from the fact that they are formed from nucleic acids. As such, their pharmacologic activity can be controlled by a matched, complementary oligonucleotide active control agent (the Watson-Crick base pair complement of a fraction of the agent to be controlled), which can bind
'/>"/>

SOURCE Regado Biosciences
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Regado Biosciences to Present at the BioPharm America 2009 Conference on September 17, 2009
2. Regado Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2009 on September 11, 2009
3. Regado Biosciences to Present at the Rodman & Renshaw Global Investment Conference on September 10, 2009
4. Regado Biosciences Announces First Patient Enrolled In Phase 1 Study Of Subcutaneously Administered Reg1 Anticoagulation System
5. Regado Biosciences Expands Medical Advisory Board
6. Regado Biosciences Establishes Medical Advisory Board
7. Dr. Steven L. Zelenkofske Joins Regado Biosciences as Senior Vice President, Clinical and Medical Affairs and Chief Medical Officer
8. Regado Biosciences To Present at the 27th Annual J.P. Morgan Healthcare Conference
9. Ellen McDonald Joins Regado Biosciences as Senior Vice President of Business Operations and Chief Business Officer
10. Regado Biosciences to Present at the Piper Jaffray Health Care Conference on Tuesday, December 2, 2008
11. David J. Mazzo, Ph.D., Joins Regado Biosciences as President and CEO
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... is available in German . ... Universitt Mnchen (TUM) have demonstrated a new kind of ... that future computer chips could be based on three-dimensional ... main enabling technology of the semiconductor industry CMOS ... TUM researchers and collaborators at the University of Notre ...
(Date:9/30/2014)... 30, 2014 Pacific Northwest Biotechnology, LLC ... Global Markets Direct,s, ,Pacific Northwest Biotechnology, LLC ... overview of the Pacific Northwest Biotechnology, LLC,s pharmaceutical ... comprehensive information on the current therapeutic developmental pipeline ... analysis at various stages, therapeutics assessment by drug ...
(Date:9/30/2014)... Shimadzu Scientific Instruments has released ... highly precise tool for measuring displacement in rubber ... 1000-mm maximum movement distance, the DSES-1000 can measure ... length of 10 mm. In addition, it achieves ... stroke and within +/- 100 µm below 50-mm ...
(Date:9/30/2014)... Over the last decade, the laboratory filtration market ... and increased acceptance of new filtration technologies in end ... are also catalyzing the growth of laboratory filtration market. ... grow at a strong CAGR during the forecast period ... million by 2019. The market is mainly driven by ...
Breaking Biology Technology:A new dimension for integrated circuits: 3-D nanomagnetic logic 2A new dimension for integrated circuits: 3-D nanomagnetic logic 3Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 2Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 2Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 3Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 4Global Laboratory Filtration Market To See 7.0% CAGR to 2019 Says a Research Report Available at ReportsnReports.com 5
... May 9 Genetic,Immunity, a US/Hungarian clinical-stage Company ... targeted immune amplification, announced,today that the Company will ... Global Healthcare Conference to be held May 19-20, ... Monte Carlo, Monaco. The Company,s President,and Chief Executive ...
... today,announced that Scott Jackson has been appointed Chief ... as Head of Commercial,Development., "We are delighted ... brings more than 20,years of pharmaceutical experience, including ... said Dr. Joseph Mollica,Chairman of Celator,s Board of ...
... 9 Inverness Medical,Innovations (Amex: IMA ... of Matria Healthcare, Inc. was successfully completed ... today, May 9, 2008. Matria,headquartered in Marietta, ... in the areas of women,s and,children,s health, ...
Cached Biology Technology:Genetic Immunity To Present at the Rodman & Renshaw 5th Annual Global Healthcare Conference 2Celator(R) Pharmaceuticals Announces Appointment of Scott Jackson as CEO 2Inverness Medical Innovations Completes Acquisition of Matria Healthcare, Inc. 2
(Date:9/30/2014)... to know what goes wrong with your muscles because of ... what "normal" actually is. That,s where a new research report ... FASEB Journal comes in. In the report, a ... molecules that can help scientists "see" which genes are active ... found never-before-detected gene activity and that men have approximately 400 ...
(Date:9/30/2014)... , Sept. 30, 2014  Spectra ... solutions for the biotech and power generation ... new RECONN Bioprocess Manager, an easy-to-use and ... geared towards bioprocess development laboratories. ... disparate bioreactor and analyzer systems. Accessing and ...
(Date:9/30/2014)... -- Winners of The Economist,s prestigious Innovation awards 2014 ... place at the JW Marriott Hong Kong on Friday, October 10 ... their experiences and the lessons those hold for others. The awards, ... the past decade, will be presented at a ceremony in ... will be the first time the ceremony has come to ...
Breaking Biology News(10 mins):Scientists identify which genes are active in muscles of men and women 2Spectra Automation Introduces RECONN Bioprocess Manager 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7
... Reportlinker.com announces that a new market research ... Global Biometrics Industry ... the worldwide markets for Biometrics in Thousands of ... Identification System), Non-AFIS/Finger Scan, Hand Geometry, Iris/Retinal Scan, ...
... University today announced a partnership to advance the use ... alternative energy source. The effort involves entrepreneurs John ... biodiesel in Afghanistan as a means to achieve multiple ... a new, sustainable economy in the country. ...
... URBANA As consumer demand for naturally raised ... Illinois have discovered that naturally raised beef can be ... a substantial premium is offered to cover additional production ... without hormones or antibiotics, whereas traditional systems take advantage ...
Cached Biology News:Reportlinker Adds Global Biometrics Industry 2Reportlinker Adds Global Biometrics Industry 3Reportlinker Adds Global Biometrics Industry 4Reportlinker Adds Global Biometrics Industry 5Reportlinker Adds Global Biometrics Industry 6Reportlinker Adds Global Biometrics Industry 7Reportlinker Adds Global Biometrics Industry 8Reportlinker Adds Global Biometrics Industry 9Reportlinker Adds Global Biometrics Industry 10Reportlinker Adds Global Biometrics Industry 11Reportlinker Adds Global Biometrics Industry 12Reportlinker Adds Global Biometrics Industry 13Reportlinker Adds Global Biometrics Industry 14Reportlinker Adds Global Biometrics Industry 15Reportlinker Adds Global Biometrics Industry 16Reportlinker Adds Global Biometrics Industry 17Reportlinker Adds Global Biometrics Industry 18Reportlinker Adds Global Biometrics Industry 19Reportlinker Adds Global Biometrics Industry 20Reportlinker Adds Global Biometrics Industry 21Reportlinker Adds Global Biometrics Industry 22Reportlinker Adds Global Biometrics Industry 23Syracuse University partners with Arden-Fox to advance DOD's Net Zero Energy Initiative 2Syracuse University partners with Arden-Fox to advance DOD's Net Zero Energy Initiative 3Can naturally raised beef find its place in the industry? 2
... Derivation Kit is intended for the ... delayed blastocysts in serum-free conditions. ... Clonal Grade Medium Basal ... Medium Trypsin Solution Gelatin Solution ...
AedestaTM Animal Organ/Tissue Perfusion Soln....
RAT ANTI MOUSE JAM-2 Immunogen: Recombinant soluble JAM-2...
casein kinase 2, alpha 1 polypeptide, transcript variant 2, mRNA (cDNA clone MGC:15232 IMAGE:4121882), complete cds...
Biology Products: