Navigation Links
Reality check for DNA nanotechnology
Date:12/13/2012

esired structures.

Observing this process in unprecedented detail, the TUM researchers discovered that all of the action takes place within a specific and relatively narrow temperature range, which differs depending on the design of the object. One practical implication is that, once the optimal temperature for a given design has been determined, DNA self-assembly nanomanufacturing, in essence could be accomplished through fast processes at constant temperatures. Following up on this lead, the researchers found that they could "mass-produce" objects made from hundreds of DNA strands within minutes instead of days, with almost no defective objects or by-products in the resulting batch.

"Besides telling us that complex DNA objects are manufacturable," Dietz says, "these results suggest something we hardly dared to imagine before that it might be possible to assemble DNA nanodevices in a cell culture or even within a living cell."

From the viewpoint of fundamental biology, the most intriguing result of these experiments may be the discovery that DNA folding resembles protein folding more closely than anticipated. Chemically and structurally, the two families of biomolecules are quite different. But the researchers observed clearly defined "cooperative" steps in the folding of complex DNA objects, no different in principle from mechanisms at work in protein folding. They speculate that further experiments with self-assembly of designed DNA objects could help to unravel the mysteries of protein folding, which is more complex and less accessible to direct study.


'/>"/>

Contact: Patrick Regan
regan@zv.tum.de
49-089-289-10515
Technische Universitaet Muenchen
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Terminator-style info-vision takes step towards reality
2. SpermCheck® Fertility, the Only FDA Approved At-Home Screening Test for Men to Determine Normal or Low Sperm Count, Now Available to Couples Planning or Struggling to Conceive
3. Nanotechnology helps scientists keep silver shiny
4. Tel Aviv University to spearhead groundbreaking nanotechnology consortium
5. Breakthrough in nanotechnology
6. Shape-shifting materials are goal of new nanotechnology project
7. Syracuse University researchers use nanotechnology to harness power of fireflies
8. Nanotechnology for Drug Delivery: Global Market for Nanocrystals
9. McLean Report on nanotechnology that may enhance medication delivery and improve MRI performance
10. Notre Dame paper examines nanotechnology-related safety and ethics problem
11. UCF scientists use nanotechnology to hunt for hidden pathogens
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Reality check for DNA nanotechnology
(Date:9/23/2014)... 23, 2014 This is a ... of the Phenolic Resin industry in Global and ... industry, including definitions, applications and industry chain structure. ... are provided with a focus on history, developments, ... comparison between the international and Chinese situation is ...
(Date:9/23/2014)... ATCC, the premier global biological materials resource ... appointments to the senior leadership team. Barbie Bigelow has ... Technology and Dr. Maryellen de Mars also joins as ... roles are new positions at ATCC. ... ATCC described the additions as part of a revitalization ...
(Date:9/23/2014)... Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced three ... to $5 million. The orders are all odour control projects ... continue to see new orders coming in," said Peter ... has climbed to over $11 million." About ... company that designs, manufactures and distributes a comprehensive line of ...
(Date:9/23/2014)... This is a professional and in-depth ... (IPA) industry. The report provides a basic overview ... chain structure. Global market analysis and Chinese domestic ... history, developments, trends and competitive landscape of the ... situation is also offered. , The report ...
Breaking Biology Technology:Phenolic Resin Industry (International, China) Development Policy and Plan Now Available at ReportsnReports.com 2ATCC Announces New Appointments to its Leadership Team 2ATCC Announces New Appointments to its Leadership Team 3(IPA) Isopropanol Industry International & China Development Trend Analysis Now Available at DeepResearchReports.com 2(IPA) Isopropanol Industry International & China Development Trend Analysis Now Available at DeepResearchReports.com 3
... Chiral Chemistry Adds to CML,s Technical ... ... Major Laboratories,announces the appointment of University of Illinois Professor John Hartwig,as ... of catalysis to the synthesis of amines, halogens, and a,variety of ...
... Amarin Corporation plc,(NASDAQ: AMRN ) ("Amarin" or ... of Amarin, will present at the Acumen,BioFin Rodman & ... 12 noon Eastern time. The conference will be held ... New York. The presentation will be simultaneously webcast ...
... The Board of,Directors of Shire plc (LSE: SHP, ... announces today that David Mott will,join the Board ... Mr Mott is Chief Executive Officer and ... to in 2000. He joined MedImmune in 1992 ...
Cached Biology Technology:Cambridge Major Appoints Professor John Hartwig as Scientific Advisor 2Amarin Corporation to Present at Acumen BioFin Rodman & Renshaw Ninth Annual Healthcare Conference 2Amarin Corporation to Present at Acumen BioFin Rodman & Renshaw Ninth Annual Healthcare Conference 3David Mott Appointed Non Executive Director at Shire 2David Mott Appointed Non Executive Director at Shire 3
(Date:9/22/2014)... (Sept. 22, 2014) As genetic sequencing technologies continue ... is a critical need to establish appropriate policies and ... experts have said. A special policy issue of the ... online today and edited by experts with the Center ... of Medicine gives policy makers the tools to jumpstart ...
(Date:9/22/2014)... key molecular cog in a plant,s biological clock ... based on temperature. , Transcription factors, or genetic switches, ... such as light, rain, soil quality, or even ... USC has isolated one, called FBH1, that reacts to ... needed while in keeping it on a consistent track. ...
(Date:9/22/2014)... in the country selected by the National Institutes ... Award a $2 million grant designed to ... sciences graduate trainees to career opportunities that go ... taken. , The award funds development of the ... program. It includes courses, seminars, shadowing, mentoring and ...
Breaking Biology News(10 mins):Experts provide much-needed policy analysis for clinical integration of next generation sequencing 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 3Genetic switch regulates a plant's internal clock based on temperature 2Rutgers receives $2 million grant to prepare biomedical students for roles in industry 2Rutgers receives $2 million grant to prepare biomedical students for roles in industry 3
... There are 300 million cases of malaria each year ... deaths occur in Africa, mostly in young children. One ... against malaria is drug resistance; resistance to chloroquine (CQ), ... throughout Africa, and resistance to sulfadoxine-pyrimethamine (SP), the first-developed ...
... detection system developed by Carnegie Mellon University scientists has ... to results being presented at the 36th Lunar and ... the first time a rover-based automated technology has been ... serves as a test bed for technology that could ...
... the bloodstream or under the skin to continuously monitor ... challenge for analytical chemists and biomedical engineers. The problem ... ways that interfere with their ability to accurately measure ... surface of implanted sensors or blood vessels contract around ...
Cached Biology News:Reducing malarial transmission in Africa 2Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert 2Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert 3Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert 4Polymers with copper show promise for implanted sensors 2Polymers with copper show promise for implanted sensors 3
... bottoms,• Nonreversible lids with ... contamination,• Individual alphanumerical codes ... footprint for ease in ... cell attachment,• Sterilized by ...
... is a G1 cyclin required for G1-phase ... a proto-oncogene. cyclin D2 can phosphorylate ... Species Reactivity: Human, Mouse, and Rat. ... is particularly well suited for neutralization of ...
... combines shaking and rocking for maximal fluid movement. ... mm stainless steel or acrylic platform, it is ... operation. The platform angle is easily adjusted from ... action and rotation speed of platform is adjusted ...
... PROTEAN II xi 2-D system runs both gel dimensions ... tube gels can be separated in a single run ... cooling core in much the same manner as the ... the second-dimension slab gels may be cast in the ...
Biology Products: