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Real Time Genomics and J. Craig Venter Institute Embark on Strategic Research Initiative
Date:5/1/2013

SAN FRANCISCO BAY AREA, California (PRWEB) May 01, 2013

Real Time Genomics, Inc. (RTG), the genome analytics company, today announced a long-term strategic collaboration with the J. Craig Venter Institute (JCVI), a not-for-profit genomic research institute, aimed at understanding and analyzing the genetic changes that induced pluripotent stem cells may acquire during the process of differentiation. RTG and JCVI also announced today a collaboration to discover and validate highly accurate human variant information using the Venter human reference diploid genome and associated orthogonal information. The teams will deposit this information into the public databases for use by the life sciences community. The two organizations hope to define best practices and to create standardized reference datasets for the genome sequencing community.

“There is considerable interest in understanding the nature of de novo mutations that are acquired during reprogramming and differentiation of iPSCs. These mutations might affect how iPSCs behave as disease models and could limit the therapeutic use of these cells, but there are many pitfalls in analyzing sequence data to locate and interpret these rare mutations,” said Mark Adams, Scientific Director for the J. Craig Venter Institute. “Since sequencing and publishing the Venter reference human genome in 2007, we have built a significant dataset around this genome and want to help others leverage the information to improve their own research. RTG is an ideal partner for these projects because of their ability to rapidly analyze data from multiple sequencing platforms with improved accuracy of the resulting variant catalog. We are excited to be working with them on these two important collaborations.”

As part of the collaboration, JCVI will be using the RTG platform and working directly with RTG scientists to identify SNPs, indels, structural variants and de novo mutations in data f
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