Navigation Links
ReachBio Launches HemoRANK-TKI Service Package for Predicting Myelotoxicity of New Tyrosine Kinase Inhibitors
Date:9/15/2009

SEATTLE, Sept. 15 /PRNewswire/ -- ReachBio LLC announced today the launch of HemoRANK(TM)-TKI, an in vitro assay service package that helps predict the potential of novel therapeutic tyrosine kinase inhibitors (TKIs) to cause clinical hematotoxicity (myelotoxicity or neutropenia). This assay system is designed to help biotechnology and pharmaceutical companies that are developing novel therapeutic TKIs gain insight into the likelihood and degree to which their compounds might cause neutropenia in patients and thus aid in lead candidate selection, structure-toxicity relationship research, and other areas of non-clinical and investigative toxicology research.

(Logo:http://www.newscom.com/cgi-bin/prnh/20080226/REACHBIOLOGO)

The HemoRANK(TM)-TKI contract assay service package is a standardized test system in which one or more novel TKIs are run in robust in vitro human bone marrow progenitor assays (CFU-GM assays) in parallel with a standard panel of up to 6 TKIs that are currently approved for therapeutic use. The TKIs available for the standard panel (Lapatinib, Erlotinib, Sorafenib, Imatinib, Sunitinib and Dasatinib) have known different levels of clinical myelotoxicity, as reported in the medical literature. The rank order of in vitro IC(50) values for these compounds obtained by the HemoRANK(TM) system correlates with the degree to which they cause neutropenia in the clinic. Novel compounds tested within the system are ranked against the standard panel and informed predictions can then be made regarding the likely level of clinical neutropenia they will cause. Testing against a reduced panel of the client's choosing or against blinded or unblinded controls provided directly by the client is also an option.

According to Dr. Emer Clarke, Chief Scientific Offi
'/>"/>

SOURCE ReachBio LLC
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. ReachBio Partners with Axiogenesis to Distribute Novel Cell-Based Products in North America
2. Research Triangle Area Health Care Collaborative Launches Bridges to Excellence(R) Initiative to Improve Quality and Lower Costs
3. Novozymes Launches Enzyme to Reduce Acrylamide in Food
4. Enova Medical Launches Exos Corporation
5. Elekta Launches New Linear Accelerator at 2007 ESTRO to Expand Cancer Treatment Availability
6. Signalifes Dr. Harmison Launches Award-Winning Ambulatory Heart Monitor
7. ThirdBiotech Networking Group Launches
8. BioReliance Launches Next-Generation Genotoxicity Screening Service
9. Midwest Research Institute Launches Center for Biological Safety and Security (CBS2)
10. BioReliance Corporation Launches iNet(TM) for Online Results Tracking of Biological Safety Tests
11. Kingfisher Healthcare Launches Breakthrough Product in Europe
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... 3, 2015 E-QURE Corp. (OTCQB: ... its Bio-electrical Signal Therapy device ("BST Device"), a new ... to heal chronic wounds, today announced that the Company ... Israeli distributor specializing in medical devices, for the marketing ... is a 70 years old, sales, marketing and distribution ...
(Date:8/3/2015)... NEW YORK , August 3, 2015 ... "Global Market Study on 3D Cell Culture: ... published by Persistence Market Research, the global 3D cell culture ... is expected to expand at a CAGR of 29.1% ... View Full Report with TOC:  http://www.persistencemarketresearch.com/market-research/3d-cell-cultures-market.asp ...
(Date:8/3/2015)... ... August 03, 2015 , ... ... vacuum pumps to its comprehensive line of analytical laboratory equipment. With optimized features, ... versatile pumps provide a chemically resistant and maintenance-free solution for a broad range ...
(Date:7/31/2015)... ... 31, 2015 , ... Global Resorcinol Market 2015-2019 is a ... the global resorcinol industry. The report highlights the various growth prospects and the ... analysis of primary and secondary inputs from the existing players of the resorcinol ...
Breaking Biology Technology:E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4Sterlitech Launches New Line of Vacuum Pumps 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4
... San Francisco, CA, March 18, 2011 Cytokinetics, Incorporated ... in the March 18, 2011 issue of the journal ... by an investigational drug candidate, omecamtiv mecarbil, and the ... for patients with systolic heart failure. This publication ...
... Quest Diagnostics Incorporated (NYSE: DGX ), ... its ColoVantage test has been approved by New York ... in the state. It is believed to be the ... blood specimen to be approved by the state.   ...
... Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS ... and webcast discussing the Company,s 2010 fourth quarter and full-year ... (EDT). Michael T. Flavin, Ph.D., Chairman & Chief Executive Officer, ... also present an update on the Company. A press release ...
Cached Biology Technology:Cytokinetics announces fundamental research in cardiac myosin activation in the journal Science 2Cytokinetics announces fundamental research in cardiac myosin activation in the journal Science 3New York State Approves the Quest Diagnostics ColoVantage™ Colorectal Cancer Blood Test 2New York State Approves the Quest Diagnostics ColoVantage™ Colorectal Cancer Blood Test 3Advanced Life Sciences to Host 2010 Fourth Quarter and Full-Year Financial Results Conference Call and Webcast 2
(Date:7/21/2015)... OXFORD, Connecticut , July 21, 2015 /PRNewswire/ ... the "Company"), a biometric authentication company focused on ... the Wocket® smart wallet, announces that it has ... Tokenization System and Method. This ... that not only authorizes an account, but also ...
(Date:7/9/2015)... JOSE, Calif. , July 9, 2015  Synaptics ... interface solutions, announced today that it will report financial ... on Thursday, July 30, 2015 after the close of ... for analysts and investors at 2:00 p.m. PT (5:00 ...   To participate on the live call, ...
(Date:7/8/2015)... LAKES , N.J. and NEW YORK ... Company) and Guidepoint today announced BD ... start-up healthcare companies with free access to Guidepoint,s expert ... several start-ups that are developing cutting-edge technologies to improve ... a dedicated Guidepoint research manager, each start-up entrepreneur will ...
Breaking Biology News(10 mins):NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 2NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 4Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3
... Despite research efforts to find modern factors that would ... the gap is actually ancient and universal, according to ... almost every country, and the sex difference in lifespan ... said Daniel J. Kruger, a research scientist in the ...
... small, inexpensive remote-control plane as a sensing tool, also known ... team plans to test it over the Konza Prairie Biological ... performs as the team hopes, it will be made available ... it to obtain high-resolution images and reliable data. , The ...
... has been developed, which quite literally sucks the life ... place ozone-depleting chemicals, like methyl bromide, which are currently ... called metabolic stress disinfection (MSDD), was developed by Manuel ... (Journal of the Science of Food and Agriculture DOI ...
Cached Biology News:Evolutionary forces explain why women live longer than men 2K-Staters design and build a low-cost remote sensing tool for environmental studies 2K-Staters design and build a low-cost remote sensing tool for environmental studies 3
Rabbit polyclonal to SMARCA2 / BRM - ChIP Grade ( Abpromise for all tested applications). entrezGeneID: 6595 SwissProtID: P51531...
Determin interaction of your protein with Echelons lipids...
Mouse monoclonal [CAT-2] to Chloramphenicol Acetyltransferase...
Anti-Human Complement Component C4c, IgY fraction (Polyclonal) (chicken IgY)...
Biology Products: