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Raven biotechnologies to Provide Updates on Oncology Pipeline With Four AACR Presentations
Date:2/12/2008

- Lead Clinical Program and Two Clinical Candidates Featured -

SOUTH SAN FRANCISCO, Calif., Feb. 12 /PRNewswire/ -- Raven biotechnologies, inc., a privately held company focused on the discovery and development of monoclonal antibody therapeutics (MAbs) for cancer, announced four abstracts have been selected for presentation at the meeting of American Association for Cancer Research being held in San Diego on April 12-16, 2008.

"We are pleased to have this opportunity to present important data on both RAV12, Raven's lead therapeutic antibody entering Phase 2 development for the treatment of adenocarcinomas and the promising near-term clinical candidates in our oncology pipeline," stated George Schreiner, M.D., Ph.D., chief executive officer of Raven biotechnologies. "Raven will present significant new data on RAV12 supporting the chemotherapeutic synergies that inform its impending phase 2 trials. In addition, recent discoveries concerning novel epitopes and effector mechanisms associated with two new antibodies targeting cancer stem cells will be presented for the first time. Both antibodies are slated for clinical development. Finally, having advanced the technology to culture cancer stem cells on a sustained basis in vitro, we will present their in vivo biology, using prostate cancer stem cells as an important new model system for understanding the growth and metastasis of human cancer."

The presentations are scheduled as follows:

Oral Presentation in a Minisymposium Session

The anti-B7-H3-4Ig antibody TES7 recognizes cancer stem cell lines, modulates angiogenic factor secretion, and exhibits potent anti-tumor activity in vivo

Session ID: Experimental and Molecular Therapeutics 24

Date and Time: Monday, April 14, 2008, 1:00 PM

Abstract Number: 2555

Poster Sessions

Human prostate cancer stem cell line spontaneously metastasizes in vivo

Session ID: Tumor
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SOURCE Raven biotechnologies, inc.
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