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RainDance and Scripps to Collaborate on Targeted Sequencing for 'Wellderly' Study
Date:8/28/2008

ncy of its second-generation genome sequencing technology for the study's large number of samples, Scripps will need a method of isolating biologically relevant genomic loci on the megabase scale. RainDance's Sequence Enrichment application leverages the RainStorm technology to enable researchers to perform millions of individual PCR reactions per day using conventional thermocyclers. The application can achieve high levels of DNA amplification using small amounts of sample for a theoretically unlimited number of targeted loci.

"RainDance's system can achieve this performance while maintaining a uniform representation across all targeted loci -- greatly increasing the capacity of STSI second-generation DNA sequencers and dramatically improving their efficiency," said McNary.

About Scripps Translational Science Institute

Scripps Translational Science Institute (STSI) is an initiative of Scripps Health and The Scripps Research Institute that supports basic research and clinical programs focused on defining the genes that underlie susceptibility to disease, and will take these findings into drug discovery programs and clinical trials. STSI's work involves genotyping tens of thousands of individuals of diverse ancestry in an attempt to identify and define genes responsible for major disease and the underpinnings of health.

The identification of these genes will lead to drug discovery and gene-specific clinical trials. STSI, in conjunction with the National Institutes of Health (NIH) Clinical Translational Science Award (CTSA) consortium, is transforming how clinical and translational research is conducted, ultimately enabling researchers to provide new treatments more efficiently and quickly to patients. To learn more about the Wellderly Study, call 1-800-SCRIPPS. For more information on STSI, visit http://www.stsiweb.org.

About Scripps Health

Founded in 1924 by philanthropist E
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SOURCE RainDance Technologies, Inc.
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