Navigation Links
RainDance and Scripps to Collaborate on Targeted Sequencing for 'Wellderly' Study

LEXINGTON, Mass., Aug. 28 /PRNewswire/ -- RainDance Technologies, Inc., a provider of innovative droplet-based solutions for human health and disease research, today announced a collaboration with the Scripps Translational Science Institute (STSI) to utilize RainDance's new RainStorm(TM) technology as a solution to a key bottleneck in large-scale targeted sequencing studies.

"RainDance is proud to support STSI in its exciting effort to discover inherited genetic variations that may play a role in preserving health," said Chris McNary, President and Chief Executive Officer, RainDance Technologies. "We believe our collaboration will accelerate the completion of the program's research objectives by using RainDance's Sequence Enrichment application to enhance the efficiency of STSI's next-generation sequencing technology. In addition, our participation will help optimize experimental procedures as we prepare for release of our platform in the fourth quarter," McNary said.

STSI's genomic researchers are now looking to America's healthy elderly, known as the wellderly -- those 80 years and older with no history of chronic disease -- to help them unlock the genetic secrets behind lifelong health. The Wellderly Study is currently recruiting volunteers from across America to donate their DNA to the project's gene bank. These samples will be studied by STSI researchers to uncover the protective elements of the human genetic code. RainDance's initial work will be a proof-of-principle study to show the effectiveness of its RainStorm technology for amplifying a large number of genomic loci across a diverse set of samples.

"Looking at the genes of healthy elderly people is a unique approach to understanding the underpinning biology of health," said Eric J. Topol, M.D., Director of Scripps Translational Science Institute. "This new technology will assist us in our effort to unlock these genetic secrets of lifelong health."

To maximize the efficiency of its second-generation genome sequencing technology for the study's large number of samples, Scripps will need a method of isolating biologically relevant genomic loci on the megabase scale. RainDance's Sequence Enrichment application leverages the RainStorm technology to enable researchers to perform millions of individual PCR reactions per day using conventional thermocyclers. The application can achieve high levels of DNA amplification using small amounts of sample for a theoretically unlimited number of targeted loci.

"RainDance's system can achieve this performance while maintaining a uniform representation across all targeted loci -- greatly increasing the capacity of STSI second-generation DNA sequencers and dramatically improving their efficiency," said McNary.

About Scripps Translational Science Institute

Scripps Translational Science Institute (STSI) is an initiative of Scripps Health and The Scripps Research Institute that supports basic research and clinical programs focused on defining the genes that underlie susceptibility to disease, and will take these findings into drug discovery programs and clinical trials. STSI's work involves genotyping tens of thousands of individuals of diverse ancestry in an attempt to identify and define genes responsible for major disease and the underpinnings of health.

The identification of these genes will lead to drug discovery and gene-specific clinical trials. STSI, in conjunction with the National Institutes of Health (NIH) Clinical Translational Science Award (CTSA) consortium, is transforming how clinical and translational research is conducted, ultimately enabling researchers to provide new treatments more efficiently and quickly to patients. To learn more about the Wellderly Study, call 1-800-SCRIPPS. For more information on STSI, visit

About Scripps Health

Founded in 1924 by philanthropist Ellen Browning Scripps, Scripps Health is a $2 billion non-profit community health system based in San Diego, California. Scripps treats a half-million patients annually through the dedication of 2,600 affiliated physicians and 12,200 employees among its five acute-care hospital campuses, home health care services, and an ambulatory care network of clinics, physician offices and outpatient centers. Recognized as a leader in the prevention, diagnosis, and treatment of disease, Scripps is also at the forefront of clinical research and graduate medical education. In 2007, Scripps committed more than $150 million in capital and facility improvements across the San Diego region while providing significant charity care to the community. Scripps Health includes: Scripps Green Hospital, Scripps Memorial Hospital Encinitas, Scripps Memorial Hospital La Jolla, two Scripps Mercy Hospital campuses, 10 Scripps Clinic locations, 10 Scripps Coastal Medical Center locations, and Scripps Home Health Care Services. More information can be found at

About The Scripps Research Institute

The Scripps Research Institute is one of the world's largest independent, non-profit biomedical research organizations, at the forefront of basic biomedical science that seeks to comprehend the most fundamental processes of life. Scripps Research is internationally recognized for its discoveries in immunology, molecular and cellular biology, chemistry, neurosciences, autoimmune, cardiovascular, and infectious diseases, and synthetic vaccine development. Established in its current configuration in 1961, it employs approximately 3,000 scientists, postdoctoral fellows, scientific and other technicians, doctoral degree graduate students, and administrative and technical support personnel. Scripps Research is headquartered in La Jolla, California. It also includes Scripps Florida, whose researchers focus on basic biomedical science, drug discovery, and technology development. Currently operating from temporary facilities in Jupiter, Scripps Florida will move to its permanent campus by 2009. More information can be found at

About RainDance Technologies, Inc.

RainDance Technologies is a provider of innovative droplet-based microfluidic solutions for human health and disease research. The speed and simplicity of the company's exciting new technology enable researchers to design experiments in ways that were previously unaffordable or unimaginable.

The company's RainStorm technology produces picoliter-volume droplets at a rate of 10 million per hour. Each droplet is the functional equivalent of an individual test tube and can contain a single molecule, reaction, or cell. This versatile technology can adapt highly referenced assays for high-speed workflows with minimized process-induced bias or error.

RainDance's initial application will focus on the targeted resequencing of the human genome -- one of the fastest-growing segments of the $1 billion DNA sequencing market. This application will enable the high-resolution analysis of genetic variation between individuals and populations at a level unmatched by current methodology.

RainDance was founded in 2004 by scientists from Harvard University; the Medical Research Centre in Cambridge, England; and the ESPCI in Paris. The promise of this technology has attracted an outstanding Scientific Advisory Board. RainDance advisers include three Nobel Prize winners: Jean-Marie Lehn (Chemistry, 1987), Aaron Klug (Chemistry, 2002), and Sir Richard Roberts (Physiology or Medicine, 1993), as well as Sir Gregory Winter, joint head of the British Division of Protein and Nucleic Acids Chemistry at the Medical Research Council's Laboratory of Molecular Biology in Cambridge.

For more information, please visit

SOURCE RainDance Technologies, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. RainDance Technologies Appoints Olex Vice President, System Development
2. RainDance Appoints Kelly Chief Operating Officer
3. RainDance Announces Company Relocation and Manufacturing Startup
4. RainDance Appoints Becker Chief Commercial Officer
5. RainDance Technologies Appoints McNary President and CEO
6. Instrumentation Laboratory Ships 1000th GEM Premier 4000 Analyzer to Scripps Health
7. The Scripps Translational Science Institute Joins The MetaMiner Cardiac Consortium
8. Cyntellect to Collaborate With the Burnham Institute for Medical Research
9. Cellumen to Collaborate With the NCTR of the FDA to Apply Cellular Systems Biology (CSB(TM)) to Predictive Toxicology
10. ZyGEM and DIAGNOTEC Collaborate on Diagnostics for Detecting a Devastating Virus Attacking Salmon
11. LabCorp(R) and Vanda Pharmaceuticals Collaborate to Offer Genetic Tests
Post Your Comments:
(Date:11/25/2015)... November 25, 2015 2 nouvelles études ... les différences entre les souches bactériennes retrouvées dans ... des êtres humains . Ces recherches  ouvrent une ... la prise en charge efficace de l,un des ... les chats .    --> 2 nouvelles ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... Organization of Black Aerospace Professionals (OPBAP) has been formalized with the signing of ... team leaders met with OPBAP leaders Capt. Karl Minter and Capt. Albert Glenn ...
(Date:11/24/2015)... ... November 24, 2015 , ... The United States Golf Association ... 2016 USGA Green Section Award. Presented annually since 1961, the USGA Green Section Award ... work with turfgrass. , Clarke, of Iselin, N.J., is an extension specialist ...
(Date:11/24/2015)... Florida (PRWEB) , ... November 24, 2015 , ... ... biggest event of the year and one of the premier annual events for ... and ran from 8–11 November 2015, where ISPE hosted the largest number of ...
Breaking Biology Technology:
(Date:11/19/2015)...  Although some 350 companies are actively involved in ... companies, according to Kalorama Information. These include Roche Diagnostics, Hologic, ... share of the 6.1 billion-dollar molecular testing market, according ... Molecular Diagnostic s .    ... by one company and only a handful of companies ...
(Date:11/17/2015)... Paris from 17 th ... Paris from 17 th until 19 th ... leader, has invented the first combined scanner in the world ... scanning surface. Until now two different scanners were required: one ... both on the same surface. This innovation is an ...
(Date:11/17/2015)... , Nov. 17, 2015 Pressure BioSciences, ... in the development and sale of broadly enabling, pressure ... life sciences industry, today announced it has received gross ... $5 million Private Placement (the "Offering"), increasing the total ...  One or more additional closings are expected in the ...
Breaking Biology News(10 mins):